CBX8 and CCDC57

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CBX8	CCDC57
Gene Name		chromobox homolog 8	coiled-coil domain containing 57
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Single-stranded RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Methylated Histone Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Histone Ubiquitination
Pathways		Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		42 interactors: BMI1 CALCOCO2 CCDC136 CCDC57 EEF1G FSD2 GOLGA2 GPRASP2 HAP1 HIST3H3 HMBOX1 IKZF1 KAT5 KAT7 KCTD9 KIFC3 KRT40 LZTS2 MID2 MLLT1 MLLT3 MTUS2 PAXIP1 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 PHC2 PNMA2 RING1 RNF2 RPGRIP1 SETDB1 SOX5 TFCP2 TRAF2 TSGA10 UNC119 USP11 USP7 ZBTB14	42 interactors: AES AQP1 ARL4A CBX8 CCDC120 CDC20B CEP57L1 CWF19L2 FAM161A FAM50B FAM90A1 GPKOW HAUS1 HBA2 KIAA0368 LENG1 LINC00526 MFAP1 NAPRT NELFE NUMA1 PER1 PPHLN1 PPP1R18 PRAM1 PRPF31 PRR3 PTPN7 RAB3IL1 ROBO3 SFI1 SIRPA TBC1D22B TMEM100 TSGA10IP USP15 USP2 UTP14C ZFC3H1 ZGPAT ZMAT2 ZNF417
Entrez ID		57332	284001
HPRD ID		13006	14150
Ensembl ID			ENSG00000176155
Uniprot IDs		Q9HC52	Q2TAC2
PDB IDs		3I91
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Histone Modification Chromatin Modification Chromosome Organization Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone Ubiquitination Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Biosynthetic Process Histone H2A Monoubiquitination Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Histone H2A Ubiquitination Peptidyl-lysine Modification Regulation Of Metabolic Process Histone Monoubiquitination Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Ubiquitination Organelle Organization Histone Acetylation Protein Modification By Small Protein Conjugation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Monoubiquitination Anterior/posterior Pattern Specification Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Segment Specification Cellular Protein Modification Process Cellular Response To Reactive Oxygen Species	Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transcription From RNA Polymerase II Promoter Photoperiodism Entrainment Of Circadian Clock Bicarbonate Transport Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Nicotinate Nucleotide Salvage
Tagcloud ?		aims approaches beings blotting causes chromobox colon conclude cultured express facilitating hct116 homolog igf1 igf1r knockdown leading line overexpression pathogenesis proliferation promote promoting real reports rt silencing unclear western
Tagcloud (Difference) ?		aims approaches beings blotting causes chromobox colon conclude cultured express facilitating hct116 homolog igf1 igf1r knockdown leading line overexpression pathogenesis proliferation promote promoting real reports rt silencing unclear western
Tagcloud (Intersection) ?