SMURF1 and PAK1

  • Number of citations of the paper that reports this interaction (PMID 15761153)
  • 154
  • Data Source:
  • HPRD (in vivo)

SMURF1

PAK1

Gene Name SMAD specific E3 ubiquitin protein ligase 1 p21 protein (Cdc42/Rac)-activated kinase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 98 interactors: ANAPC5 AP2B1 APBB2 APP ARHGAP15 ARHGAP31 ARHGEF9 ARL14 ARL4D ASH2L AVEN AXIN1 CCM2 CDC40 CDK14 CDKL1 CSNK2A2 CUL5 CXXC1 DNAJC7 DUSP13 DVL2 ECSIT ELP3 ESR1 ETV6 FBXL15 FBXO30 FCHO1 GNG11 GRIPAP1 HDGFRP3 ING2 INPP5B IRAK2 JUNB LATS1 LHX9 LIMS1 LONRF3 MAP3K2 MAP3K3 NAA16 NDFIP2 NEDD8 OXSR1 PAK1 PAK1IP1 PDLIM7 PLEKHO1 POLR2A PSME3 PWP1 RASD2 RHOA RHPN2 RIPK2 RIT1 RNF11 RNF141 RPS27A RRP9 RTKN RUNX3 SASH3 SENP8 SF3A1 SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SPG20 SQSTM1 SRSF4 SRSF5 STK35 STRAP STUB1 TLN1 TNK2 TNNT1 TRAF4 TTC17 UBA52 UBB UBC UBE2D3 UBE2L3 UBTF UBXN1 USP45 USP9X WDR61 WEE1 WFS1 XPO1 83 interactors: ABI3 ACTA1 ACVR1 AKT1 APP ARHGEF2 ARHGEF6 ARHGEF7 ARPC1B BAD BAIAP2 BMPR1B BMX BRSK1 C5orf42 CASP1 CDC42 CDK11B CDK5 CDK5R1 CHORDC1 COL1A1 CRIPAK CSNK2A1 CSNK2A2 DSCAM DYNLL1 DYNLL2 DYRK1B EGFR ELF3 ERBB2 ESR1 FLNA FOXL2 FOXO1 FRS2 GIT2 GRB2 HGS HIST1H3A HIST1H4A HSP90AA1 LIMK1 MAP2K1 MAP3K1 MAPK1 MBP MYLK MYNN MYO6 NCK1 NCK2 NF2 OXSR1 PAK1IP1 PDPK1 PLCG1 PPM1F PRKCD PXN RAC1 RAF1 RHOJ RHOU SHC1 SMAD1 SMAD2 SMAD4 SMURF1 SORBS2 SORBS3 SYN1 TGFBR1 TGFBR2 TGM2 YWHAG YWHAZ ZBTB18 ZC3H7A ZNF418 ZNF823 ZNF83
Entrez ID 57154 5058
HPRD ID 06902 03995
Ensembl ID ENSG00000198742 ENSG00000149269
Uniprot IDs Q9HCE7 B3KNX7 Q13153
PDB IDs 2LAZ 2LB0 2LB1 2LTX 3PYC 1F3M 1YHV 1YHW 1ZSG 2HY8 2QME 3DVP 3FXZ 3FY0 3Q4Z 3Q52 3Q53 4DAW 4EQC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
5p  acvr2a  alters  applying  bmp  bmp1a  cleaves  cluster  copyright  dies1  furin  impairs  interferes  mapk3  micrornas  mineralization  mir  osteoblast  osteoblasts  protected  reprogramming  reserved  rights  ski  smad  smad5  systematically  tgfbr3  zfp423 
advance  belonging  cdc2  cdc42  coordinate  coordinates  coordinating  cot1  delays  dystrophy  encodes  fission  genetically  interphase  maintain  maintains  mitosis  mitotic  morphogenesis  myotonic  orb2  orb6  p34  polarity  polarized  ras1  shape  shk1  threonine 
Tagcloud (Difference) ?
5p  acvr2a  alters  applying  bmp  bmp1a  cleaves  cluster  copyright  dies1  furin  impairs  interferes  mapk3  micrornas  mineralization  mir  osteoblast  osteoblasts  protected  reprogramming  reserved  rights  ski  smad  smad5  systematically  tgfbr3  zfp423 
advance  belonging  cdc2  cdc42  coordinate  coordinates  coordinating  cot1  delays  dystrophy  encodes  fission  genetically  interphase  maintain  maintains  mitosis  mitotic  morphogenesis  myotonic  orb2  orb6  p34  polarity  polarized  ras1  shape  shk1  threonine 
Tagcloud (Intersection) ?