LENG1 and CCDC102B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		LENG1	CCDC102B
Description		leukocyte receptor cluster member 1	coiled-coil domain containing 102B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Cytoplasm Centriole Cytoskeleton
	Molecular Function	Protein Binding	Protein Binding Protein Serine/threonine Kinase Binding
	Biological Process		Centriole-centriole Cohesion
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)	Caudate activity during reward ( 28927378) Liver enzyme levels (alanine transaminase) ( 24124411) Myopic maculopathy ( 29725004) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Rostral anterior cingulate cortex volume ( 31530798)
Interacting Genes		90 interacting genes: ABI2 APP ASB12 BANP BEGAIN C14orf119 CALCOCO2 CARD10 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCHCR1 CDR2 CDR2L CEP55 CEP57L1 CEP70 CPSF7 DDIT4L DES DISC1 EVI5 EXOSC8 FSD2 GFAP GOLGA2 GOLGA6L9 HOMEZ HOOK1 HOOK2 IKZF3 ISY1-RAB43 KANK2 KASH5 KIFC3 KLF10 KRT19 KRT31 KRT35 KRT40 KRTAP10-8 LARP4 LDOC1 LRP2BP LZTS1 MAB21L3 MAD1L1 MEIS3 MID2 MIPOL1 MRPL28 MTUS2 NAB2 NAGK NECAB2 NTAQ1 NUTF2 OIP5 OSGEP PAK5 PDE4DIP PNMA1 PRKAR1B PRPH PSMB1 RABEP1 REL ROPN1 SCYL1 SPATA2 STX11 TCF4 TEPSIN TEX12 TFIP11 TMEM239 TRAF2 TRIB3 TRIM23 TRIM27 TRIM54 TSC1 UBL5 UBXN11 USHBP1 USO1 ZMYND12 ZRANB1	102 interacting genes: ABI2 AK8 ANKRD23 ARL4A ARL4D BYSL C20orf202 CACNB4 CAPN3 CCDC120 CCDC187 CCDC33 CCHCR1 CDK18 CEP19 CEP57L1 CWF19L2 DISC1 DOCK10 EFHC2 EHHADH ENKD1 EXOC5 FAM161A FAM217B FBF1 FH FLOT1 FNDC11 GEM GOPC HMG20B IKZF3 KIFC3 KPNA3 KRT75 KRTAP13-3 LENG1 LMO4 LNX1 LZTS1 MAB21L2 MAGOHB MARK1 MCM7 MEOX1 MEOX2 MFAP1 MOS MSX2 NIF3L1 NME4 NTAQ1 NXT2 PFKFB4 PHAF1 PICK1 PNMA5 POMC POP5 PPP1R13B PPP1R18 PRPF18 PSMA1 RASAL3 RCOR3 RSPH14 RTL8A RTL8B RTL8C SDCBP SFN SGF29 SH3RF2 SLIRP SMARCD1 SNAPIN SORBS3 SPATA18 SPATA2 SPG21 SYCE1 SYT17 TCEANC TCP10L TFIP11 TNNI1 TPM3 TRIM27 TRIM54 TSGA10IP TTC23 VPS52 ZBTB32 ZBTB42 ZC2HC1C ZNF20 ZNF250 ZNF572 ZNF620 ZNF688 ZNF774
Entrez ID		79165	79839
HPRD ID		13985	08038
Ensembl ID		ENSG00000105617	ENSG00000150636
Uniprot IDs		Q96BZ8	Q68D86
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Cytoskeleton Protein Binding Intermediate Filament Organization Supramolecular Fiber Organization Cytoplasm Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytoskeleton Organization Intermediate Filament Centrosome Microtubule Binding Organelle Organization Microtubule Keratin Filament Regulation Of Autophagy Response To Muramyl Dipeptide Structural Constituent Of Cytoskeleton Microtubule-based Process Structural Constituent Of Skin Epidermis CBM Complex FHF Complex	Protein Binding
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