LENG1 and CEP57L1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		LENG1	CEP57L1
Description		leukocyte receptor cluster member 1	centrosomal protein 57 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Cytoplasm Centrosome Cytoskeleton Microtubule
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Identical Protein Binding Gamma-tubulin Binding
	Biological Process
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Midgestational circulating levels of PCBs ( 28235828) Prostate cancer ( 23535732)
Interacting Genes		90 interacting genes: ABI2 APP ASB12 BANP BEGAIN C14orf119 CALCOCO2 CARD10 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCHCR1 CDR2 CDR2L CEP55 CEP57L1 CEP70 CPSF7 DDIT4L DES DISC1 EVI5 EXOSC8 FSD2 GFAP GOLGA2 GOLGA6L9 HOMEZ HOOK1 HOOK2 IKZF3 ISY1-RAB43 KANK2 KASH5 KIFC3 KLF10 KRT19 KRT31 KRT35 KRT40 KRTAP10-8 LARP4 LDOC1 LRP2BP LZTS1 MAB21L3 MAD1L1 MEIS3 MID2 MIPOL1 MRPL28 MTUS2 NAB2 NAGK NECAB2 NTAQ1 NUTF2 OIP5 OSGEP PAK5 PDE4DIP PNMA1 PRKAR1B PRPH PSMB1 RABEP1 REL ROPN1 SCYL1 SPATA2 STX11 TCF4 TEPSIN TEX12 TFIP11 TMEM239 TRAF2 TRIB3 TRIM23 TRIM27 TRIM54 TSC1 UBL5 UBXN11 USHBP1 USO1 ZMYND12 ZRANB1	85 interacting genes: AKT1 ALOX5 AP1M1 ARNT2 BRCA1 BYSL CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CDR2 CEP44 CEP55 CEP63 CEP70 CFAP206 DISC1 DVL3 DYDC1 ELOA EXOC8 FAM161A FAM9B GADD45G GOLGA1 GOLGA2 GRIPAP1 HAUS1 HDDC3 HGS IKZF1 KATNAL1 KIFC3 KLC3 KLC4 KRT13 KRT19 KRT31 KRT38 KRT40 LCOR LENG1 LMO1 LMO3 LZTS2 MAGEA1 MAGEA2B MCC MDFI MEOX2 MFAP1 MID2 MORF4L1 MTUS2 MYO15B NEFL NOTCH1 NUP62 PATJ PICK1 PKN1 PNMA5 PPL PRDM6 RAD51D RINT1 ROPN1 SNAP47 SNAPC3 TAB3 TFIP11 TRAF2 TRAPPC2L TRIM54 TRIP6 TSGA10 TXLNA TXLNB VPS28 YES1 ZGPAT ZNF572 ZNF655
Entrez ID		79165	285753
HPRD ID		13985	10792
Ensembl ID		ENSG00000105617	ENSG00000183137
Uniprot IDs		Q96BZ8	E5RFY4 E5RJH1 Q6P2R3 Q8IYX8
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Cytoskeleton Protein Binding Intermediate Filament Organization Supramolecular Fiber Organization Cytoplasm Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytoskeleton Organization Intermediate Filament Centrosome Microtubule Binding Organelle Organization Microtubule Keratin Filament Regulation Of Autophagy Response To Muramyl Dipeptide Structural Constituent Of Cytoskeleton Microtubule-based Process Structural Constituent Of Skin Epidermis CBM Complex FHF Complex	Cytoskeleton Protein Binding Cytoplasm Organelle Organization Centrosome Microtubule Organizing Center Organization Microtubule-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Microtubule Intermediate Filament Organization Centrosome Cycle Microtubule Binding Identical Protein Binding Organelle Assembly Structural Constituent Of Skin Epidermis Intermediate Filament Centriole Assembly Centriole Kinesin Complex Cytoskeleton Organization Keratin Filament Syntaxin Binding Spindle Pole Cellular Component Assembly Centriole Replication Structural Molecule Activity Microtubule Cytoskeleton Organization
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