TRIP13 and MAD2L1BP

Number of citations of the paper that reports this interaction (PubMedID 11591653)
29

Data Source:
HPRD (in vivo)

		TRIP13	MAD2L1BP
Description		thyroid hormone receptor interactor 13	MAD2L1 binding protein
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GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Chromosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Spindle Cytoskeleton Nuclear Membrane
	Molecular Function	Nucleotide Binding Transcription Coregulator Activity Protein Binding ATP Binding ATP Hydrolysis Activity Identical Protein Binding	Protein Binding
	Biological Process	Oocyte Maturation Double-strand Break Repair Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Signaling Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Cell Differentiation Oogenesis Meiotic Cell Cycle Meiotic Recombination Checkpoint Signaling	Regulation Of Exit From Mitosis Deactivation Of Mitotic Spindle Assembly Checkpoint
Pathways
Drugs
Diseases
GWAS		Pancreatic cancer ( 25086665)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		113 interacting genes: ACTMAP ADAM15 AMDHD2 ANKRD10 ARL11 ARSA ASB13 BKGD BUB1B C4orf33 CARD14 CD99 CDC20 CDIN1 CEP170B CFP CLIP4 COMT CRMP1 CRYBA2 CYB5R2 DCTN3 DDAH2 DIP2A DPYSL4 DTX2 EEF2KMT FBLN5 FBXO8 FILNC1 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 IGFN1 IL2RB INCA1 INTS11 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MBLAC1 MEAK7 METTL15 MGAT5B MORN3 MPPED2 MVP MYEOV NIF3L1 NME4 NTAQ1 PARP11 PAX9 PBLD PCMTD2 PCSK5 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 POLR2L PPP2CA PRKAA2 PRKN PRR13 PSMB8 QARS1 RBPMS RHOXF2 RNF4 SCP2 SDCBP SEC24A SELENBP1 SEMA3B SEMA4G SHARPIN SIGLEC5 SMUG1 SPMIP9 SPRYD7 SSC4D STAMBP STAMBPL1 SUMO2 TENT5B THRB TINAGL1 TNRC6A TPT1 UBE2I VDR VENTX ZMYM5 ZNF34 ZNF655	18 interacting genes: ANAPC4 CEP126 EEF1A1 HOMEZ IGSF21 KAT5 KRT15 LRIF1 MAD2L1 MAD2L2 NMI PLK1 PTN SETDB1 TP53 TRIP13 ZBTB14 ZNF202
Entrez ID		9319	9587
HPRD ID		05145	10065
Ensembl ID		ENSG00000071539	ENSG00000124688
Uniprot IDs		Q15645	Q15013
PDB IDs		5VQ9 5VQA 5WC2 6F0X 6LK0 7L9P	2QYF 6F0X
Enriched GO Terms of Interacting Partners?		Protein Binding Mitotic Checkpoint Complex Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Protein K6-linked Ubiquitination Intermediate Filament	Regulation Of Sister Chromatid Segregation Regulation Of Chromosome Segregation Regulation Of Chromosome Organization Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Chromosome Organization Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Mitotic Nuclear Division Chromosome Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Chromosome Separation Negative Regulation Of Mitotic Cell Cycle Regulation Of Ubiquitin-protein Transferase Activity Double-strand Break Repair Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process Regulation Of Mitotic Nuclear Division Establishment Of Mitotic Spindle Orientation Negative Regulation Of Cell Cycle Process Microtubule Cytoskeleton Organization Involved In Mitosis Establishment Of Mitotic Spindle Localization Negative Regulation Of Double-strand Break Repair Regulation Of Mitotic Cell Cycle Negative Regulation Of DNA Metabolic Process Negative Regulation Of DNA Repair Establishment Of Spindle Orientation Regulation Of Nuclear Division Negative Regulation Of Macromolecule Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of DNA Recombination Chromosome Organization Establishment Of Spindle Localization Negative Regulation Of Cell Cycle Nucleus Negative Regulation Of Macromolecule Biosynthetic Process Nucleolus Negative Regulation Of Metabolic Process Negative Regulation Of Ubiquitin Protein Ligase Activity Spindle Localization Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Germ Cell Development Regulation Of Protein Ubiquitination Negative Regulation Of Ubiquitin-protein Transferase Activity Promoter-specific Chromatin Binding Regulation Of Cell Cycle
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