TRIP13 and ZNF34

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		TRIP13	ZNF34
Description		thyroid hormone receptor interactor 13	zinc finger protein 34
Image			No pdb structure
GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Chromosome	Nucleus Nucleoplasm Cytosol
	Molecular Function	Nucleotide Binding Transcription Coregulator Activity Protein Binding ATP Binding ATP Hydrolysis Activity Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Oocyte Maturation Double-strand Break Repair Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Signaling Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Cell Differentiation Oogenesis Meiotic Cell Cycle Meiotic Recombination Checkpoint Signaling	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Pancreatic cancer ( 25086665)	Blood metabolite levels ( 26401656) Logical memory (immediate recall) in normal cognition ( 29274321) Type 2 diabetes ( 30054458)
Interacting Genes		113 interacting genes: ACTMAP ADAM15 AMDHD2 ANKRD10 ARL11 ARSA ASB13 BKGD BUB1B C4orf33 CARD14 CD99 CDC20 CDIN1 CEP170B CFP CLIP4 COMT CRMP1 CRYBA2 CYB5R2 DCTN3 DDAH2 DIP2A DPYSL4 DTX2 EEF2KMT FBLN5 FBXO8 FILNC1 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 IGFN1 IL2RB INCA1 INTS11 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MBLAC1 MEAK7 METTL15 MGAT5B MORN3 MPPED2 MVP MYEOV NIF3L1 NME4 NTAQ1 PARP11 PAX9 PBLD PCMTD2 PCSK5 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 POLR2L PPP2CA PRKAA2 PRKN PRR13 PSMB8 QARS1 RBPMS RHOXF2 RNF4 SCP2 SDCBP SEC24A SELENBP1 SEMA3B SEMA4G SHARPIN SIGLEC5 SMUG1 SPMIP9 SPRYD7 SSC4D STAMBP STAMBPL1 SUMO2 TENT5B THRB TINAGL1 TNRC6A TPT1 UBE2I VDR VENTX ZMYM5 ZNF34 ZNF655	44 interacting genes: ANKHD1 CYSRT1 DAZAP2 DTX2 FOXH1 GCM2 HGS HOXC8 KRTAP10-5 KRTAP26-1 KRTAP8-1 LENG8 LMO2 MAPKBP1 MKRN3 NFYC OTX1 PITX1 PITX2 PLSCR4 POU6F2 RBPMS RBPMS2 ROR2 RSPH1 RUSC1 SPAG8 TBX3 TBX6 TCF7L2 TFG TIAM1 TLE5 TLX3 TRIP13 UBAP2 VAC14 VENTX VGLL3 VPS37C WDR25 YTHDF1 ZC3H10 ZIC1
Entrez ID		9319	80778
HPRD ID		05145	11772
Ensembl ID		ENSG00000071539	ENSG00000196378
Uniprot IDs		Q15645	A0A0C4DG42 E9PNZ6 Q8IZ26
PDB IDs		5VQ9 5VQA 5WC2 6F0X 6LK0 7L9P
Enriched GO Terms of Interacting Partners?		Protein Binding Mitotic Checkpoint Complex Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Protein K6-linked Ubiquitination Intermediate Filament	DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Nucleus Sequence-specific Double-stranded DNA Binding Chromatin Regulation Of RNA Metabolic Process Regulation Of Gene Expression Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Myoblast Fate Commitment Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Embryonic Hindlimb Morphogenesis Pattern Specification Process Embryonic Morphogenesis Hindlimb Morphogenesis Cytoplasmic Stress Granule Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Transcription Regulator Complex Positive Regulation Of Macromolecule Metabolic Process Inner Ear Morphogenesis DNA Binding Outflow Tract Morphogenesis Wnt Signaling Pathway Regionalization Mitogen-activated Protein Kinase Kinase Kinase Binding Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Metabolic Process Negative Regulation Of Androgen Receptor Signaling Pathway Embryonic Digestive Tract Morphogenesis Axis Specification Sequence-specific DNA Binding DNA-binding Transcription Factor Binding Identical Protein Binding Cell Fate Specification Positive Regulation Of Metabolic Process Embryonic Limb Morphogenesis
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