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UBQLN4 and CTSB
Number of citations of the paper that reports this interaction (PMID
11162551
)
3
Data Source:
BioGRID
(two hybrid)
UBQLN4
CTSB
Gene Name
ubiquilin 4
cathepsin B
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Nuclear Proteasome Complex
Cytosolic Proteasome Complex
Perinuclear Region Of Cytoplasm
Extracellular Region
Extracellular Space
Intracellular
Nucleolus
Mitochondrion
Lysosome
Endolysosome Lumen
Melanosome
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Polyubiquitin Binding
Identical Protein Binding
Cysteine-type Endopeptidase Activity
Protein Binding
Collagen Binding
Peptidase Activity
Cysteine-type Peptidase Activity
Proteoglycan Binding
Biological Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Toll-like Receptor Signaling Pathway
Proteolysis
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Collagen Catabolic Process
Epithelial Cell Differentiation
Regulation Of Apoptotic Process
Innate Immune Response
Decidualization
Regulation Of Catalytic Activity
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Response To Thyroid Hormone Stimulus
Pathways
Toll-Like Receptors Cascades
Trafficking and processing of endosomal TLR
Collagen formation
Collagen degradation
MHC class II antigen presentation
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Adaptive Immune System
Innate Immune System
Drugs
2-Aminoethanimidic Acid
3-Amino-4-Oxybenzyl-2-Butanone
3-Methylphenylalanine
N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline
2-Pyridinethiol
Diphenylacetic Acid
N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-2-Methyl-Butane
N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-
N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE
BENZYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE
METHYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE
N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE
N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE
N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
157 interactors:
ADAM33
ADPGK
AGR2
ANKRD13D
AREG
ARL4C
ATPIF1
ATXN1
BAG6
BPIFA1
C11orf49
C1orf94
C1QTNF1
CACNA1G
CCDC107
CCDC134
CCDC136
CCDC14
CCDC33
CCL21
CD99
CDSN
CEND1
COL8A1
COPB1
CPSF6
CRIPT
CSTF2
CSTF2T
CTSB
CYB5R1
DAZAP2
DKK3
DMPK
DNAJB11
DTX2
EAPP
EDN1
EEF1A1
EFEMP2
ELF5
EPDR1
ERP27
ERP29
FA2H
FGFBP1
FKBP2
FKBP7
FZD7
GABRD
GDI1
GKAP1
GPX7
HAVCR1
HGS
HK2
HSPA13
HSPA5
IGFBP6
IGHM
IGLC1
IMMT
IMPDH2
ITPRIPL1
KLHL26
KLHL42
LAT2
MDK
MDM2
MIEF2
MIF4GD
MLLT6
MOAP1
MYDGF
NAE1
NME3
NOMO1
NOMO3
NOTCH2NL
NPHP1
NPPA
NXF1
OAT
ORC5
PBXIP1
PCDH17
PCDH8
PDIA5
PDLIM7
PELI2
PICK1
PIN1
PIP4K2B
PLA2G16
PMEPA1
PNMA1
PPIB
PPIC
PRL
PRPF40A
PSMD4
PTN
PTPRN
PTPRN2
QSOX1
RAD23A
RAI2
RBM10
RIC8A
RNF11
RNPS1
ROBO2
RPN1
RSRC2
RUNX1T1
RXRA
SCAF1
SCG2
SCG5
SCMH1
SEMG1
SERPINE1
SERPINH1
SERPINI2
SMAD3
SMAD9
SMARCB1
SPAG8
SPINT1
SPP1
SRGN
SRSF2
STAM2
STMN1
SUPT20H
TFF1
TGFB1I1
TNFRSF14
TNRC6B
TRAF2
TRIB2
TRIM32
UBQLN1
UBQLN2
UBR7
UNC119
UROS
USMG5
VIP
WAC
YWHAQ
ZBTB22
ZDHHC3
ZFPM2
ZG16
ZG16B
ZNF205
33 interactors:
A2M
ACAN
ADAMTSL4
ANXA2
ANXA7
APOE
APP
BAG6
BGLAP
CDKN1A
CST3
CST7
CSTA
CSTB
CTSD
FAM118B
HNRNPD
IGF1
INS
MARCKS
PARP1
PLAU
REN
RGS2
S100A10
SERPINB13
SLPI
SPHK1
SPINT2
SPRY2
SRPX2
UBQLN4
XRN1
Entrez ID
56893
1508
HPRD ID
05670
00287
Ensembl ID
ENSG00000160803
ENSG00000164733
Uniprot IDs
B4DZF6
Q9NRR5
P07858
PDB IDs
1CSB
1GMY
1HUC
1PBH
2IPP
2PBH
3AI8
3CBJ
3CBK
3K9M
3PBH
Enriched GO Terms of Interacting Partners
?
Regulation Of Cellular Process
Response To Stress
Positive Regulation Of Cellular Metabolic Process
Response To Stimulus
Signaling
Signal Transduction
Cell Communication
Regulation Of Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Stimulus
Multicellular Organismal Development
Positive Regulation Of Metabolic Process
Regulation Of Cell Death
Regulation Of Apoptotic Process
Regulation Of Cell Proliferation
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Transport
Organ Development
Positive Regulation Of Mitochondrion Organization
Regulation Of Cellular Localization
Regulation Of Proteolysis
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Developmental Process
Response To Organic Substance
Tissue Development
Regulation Of Metabolic Process
Positive Regulation Of Gene Expression
Anatomical Structure Development
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Catabolic Process
Regulation Of Signal Transduction
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Behavior
Regulation Of Phosphorus Metabolic Process
System Development
Protein Peptidyl-prolyl Isomerization
Regulation Of Signaling
Negative Regulation Of Cell Proliferation
Regulation Of Body Fluid Levels
Regulation Of Chemotaxis
Cell Surface Receptor Signaling Pathway
Regulation Of Phosphorylation
Cellular Localization
Defense Response
Regulation Of Mitochondrion Organization
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Cellular Component Organization
Regulation Of Protein Metabolic Process
Negative Regulation Of Catalytic Activity
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Proteolysis
Negative Regulation Of Protein Processing
Regulation Of Proteolysis
Negative Regulation Of Hydrolase Activity
Regulation Of Protein Processing
Negative Regulation Of Endopeptidase Activity
Negative Regulation Of Peptidase Activity
Negative Regulation Of Cellular Metabolic Process
Regulation Of Endopeptidase Activity
Regulation Of Peptidase Activity
Regulation Of Catalytic Activity
Regulation Of Metabolic Process
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Phosphorylation
Positive Regulation Of Fibroblast Proliferation
Regulation Of Binding
Regulation Of Growth
Regulation Of Cellular Process
Cell Differentiation
Regulation Of Phosphorus Metabolic Process
Regulation Of Fibroblast Proliferation
Regulation Of Protein Localization To Nucleus
Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Cell Proliferation
Positive Regulation Of Binding
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of Mitotic Cell Cycle
Positive Regulation Of Protein Metabolic Process
Regulation Of Cellular Component Organization
Negative Regulation Of Blood Coagulation
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Coagulation
Positive Regulation Of Cell Cycle
Developmental Process
Negative Regulation Of Wound Healing
Organ Development
Negative Regulation Of MAPK Cascade
Response To Abiotic Stimulus
Regulation Of Protein Import Into Nucleus
Regulation Of Signaling
Regulation Of Apoptotic Process
Regulation Of Body Fluid Levels
Cellular Response To Growth Factor Stimulus
Tagcloud
?
bag1
bcl2l2
bctis
ccna2
comprehend
deregulations
fgf1
fosl1
gabrp
gsn
hnepi
id2
il6r
itgb4
klf5
klk5
map2k7
microdissected
ngfb
ngfr
ontological
pappa
plau
scgb1d2
scgb2a1
serpinb5
serpine1
thbs1
thbs2
Tagcloud (Difference)
?
bag1
bcl2l2
bctis
ccna2
comprehend
deregulations
fgf1
fosl1
gabrp
gsn
hnepi
id2
il6r
itgb4
klf5
klk5
map2k7
microdissected
ngfb
ngfr
ontological
pappa
plau
scgb1d2
scgb2a1
serpinb5
serpine1
thbs1
thbs2
Tagcloud (Intersection)
?