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UBQLN4 and AREG
Number of citations of the paper that reports this interaction (PMID
16713569
)
214
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
UBQLN4
AREG
Gene Name
ubiquilin 4
amphiregulin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Nuclear Proteasome Complex
Cytosolic Proteasome Complex
Perinuclear Region Of Cytoplasm
Extracellular Space
Nucleus
Cytoplasm
Cell Surface
Integral Component Of Membrane
Molecular Function
Protein Binding
Polyubiquitin Binding
Identical Protein Binding
Cytokine Activity
Epidermal Growth Factor Receptor Binding
Protein Binding
Growth Factor Activity
Biological Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway
Cell-cell Signaling
Cell Proliferation
Positive Regulation Of Cell Proliferation
Glial Cell Proliferation
Neuron Projection Development
Response To Estradiol
Positive Regulation Of Phosphorylation
Response To Hydrogen Peroxide
Response To Peptide Hormone
Negative Regulation Of Osteoblast Differentiation
Positive Regulation Of DNA Replication
Response To Glucocorticoid
Response To CAMP
Dichotomous Subdivision Of Terminal Units Involved In Mammary Gland Duct Morphogenesis
Mammary Gland Branching Involved In Thelarche
Mammary Gland Alveolus Development
Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Pathways
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Breast size (
22747683
)
Protein-Protein Interactions
157 interactors:
ADAM33
ADPGK
AGR2
ANKRD13D
AREG
ARL4C
ATPIF1
ATXN1
BAG6
BPIFA1
C11orf49
C1orf94
C1QTNF1
CACNA1G
CCDC107
CCDC134
CCDC136
CCDC14
CCDC33
CCL21
CD99
CDSN
CEND1
COL8A1
COPB1
CPSF6
CRIPT
CSTF2
CSTF2T
CTSB
CYB5R1
DAZAP2
DKK3
DMPK
DNAJB11
DTX2
EAPP
EDN1
EEF1A1
EFEMP2
ELF5
EPDR1
ERP27
ERP29
FA2H
FGFBP1
FKBP2
FKBP7
FZD7
GABRD
GDI1
GKAP1
GPX7
HAVCR1
HGS
HK2
HSPA13
HSPA5
IGFBP6
IGHM
IGLC1
IMMT
IMPDH2
ITPRIPL1
KLHL26
KLHL42
LAT2
MDK
MDM2
MIEF2
MIF4GD
MLLT6
MOAP1
MYDGF
NAE1
NME3
NOMO1
NOMO3
NOTCH2NL
NPHP1
NPPA
NXF1
OAT
ORC5
PBXIP1
PCDH17
PCDH8
PDIA5
PDLIM7
PELI2
PICK1
PIN1
PIP4K2B
PLA2G16
PMEPA1
PNMA1
PPIB
PPIC
PRL
PRPF40A
PSMD4
PTN
PTPRN
PTPRN2
QSOX1
RAD23A
RAI2
RBM10
RIC8A
RNF11
RNPS1
ROBO2
RPN1
RSRC2
RUNX1T1
RXRA
SCAF1
SCG2
SCG5
SCMH1
SEMG1
SERPINE1
SERPINH1
SERPINI2
SMAD3
SMAD9
SMARCB1
SPAG8
SPINT1
SPP1
SRGN
SRSF2
STAM2
STMN1
SUPT20H
TFF1
TGFB1I1
TNFRSF14
TNRC6B
TRAF2
TRIB2
TRIM32
UBQLN1
UBQLN2
UBR7
UNC119
UROS
USMG5
VIP
WAC
YWHAQ
ZBTB22
ZDHHC3
ZFPM2
ZG16
ZG16B
ZNF205
8 interactors:
APP
CCND3
EGFR
KRTAP10-3
MMP9
UBQLN4
WDR92
WT1
Entrez ID
56893
374
HPRD ID
05670
00093
Ensembl ID
ENSG00000160803
ENSG00000109321
Uniprot IDs
B4DZF6
Q9NRR5
P15514
PDB IDs
2RNL
Enriched GO Terms of Interacting Partners
?
Regulation Of Cellular Process
Response To Stress
Positive Regulation Of Cellular Metabolic Process
Response To Stimulus
Signaling
Signal Transduction
Cell Communication
Regulation Of Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Stimulus
Multicellular Organismal Development
Positive Regulation Of Metabolic Process
Regulation Of Cell Death
Regulation Of Apoptotic Process
Regulation Of Cell Proliferation
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Transport
Organ Development
Positive Regulation Of Mitochondrion Organization
Regulation Of Cellular Localization
Regulation Of Proteolysis
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Developmental Process
Response To Organic Substance
Tissue Development
Regulation Of Metabolic Process
Positive Regulation Of Gene Expression
Anatomical Structure Development
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Catabolic Process
Regulation Of Signal Transduction
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Behavior
Regulation Of Phosphorus Metabolic Process
System Development
Protein Peptidyl-prolyl Isomerization
Regulation Of Signaling
Negative Regulation Of Cell Proliferation
Regulation Of Body Fluid Levels
Regulation Of Chemotaxis
Cell Surface Receptor Signaling Pathway
Regulation Of Phosphorylation
Cellular Localization
Defense Response
Regulation Of Mitochondrion Organization
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Cellular Component Organization
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Cell Morphogenesis Involved In Differentiation
Positive Regulation Of Cell Cycle
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Extracellular Matrix Organization
Extracellular Structure Organization
Cell Morphogenesis
Axon Guidance
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Locomotion
Regulation Of ERBB Signaling Pathway
Reproductive Process
Alkanesulfonate Metabolic Process
Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation
Axonogenesis
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Axon Development
Movement Of Cell Or Subcellular Component
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Visceral Serous Pericardium Development
Synaptic Growth At Neuromuscular Junction
Posterior Mesonephric Tubule Development
Adrenal Cortex Formation
Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling
Positive Regulation Of Metanephric Ureteric Bud Development
Thorax And Anterior Abdomen Determination
Astrocyte Activation
Neuron Projection Morphogenesis
Cell Activation
Regulation Of Protein Binding
Negative Regulation Of Glomerular Mesangial Cell Proliferation
Negative Regulation Of Glomerulus Development
Collateral Sprouting In Absence Of Injury
Regulation Of Protein Kinase Activity
Cell Development
Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development
Positive Regulation Of Receptor Binding
Activation Of Phospholipase A2 Activity
Zygotic Determination Of Anterior/posterior Axis, Embryo
Regulation Of Kinase Activity
Neuron Projection Development
Positive Regulation Of Phospholipase A2 Activity
Positive Regulation Of Keratinocyte Migration
Collateral Sprouting
Axon Midline Choice Point Recognition
Negative Regulation Of Cell Proliferation Involved In Kidney Development
Cell Projection Morphogenesis
Cell Part Morphogenesis
Tagcloud
?
18k
amphiregulin
atf3
biomarker
biomarkers
bleomycin
candidate
chemotherapy
cisplatin
clustered
damage
endothelial
equalled
etoposide
gdf
hmec
hscrp
mellitus
micro
microarrays
preclinical
qrt
sets
testicular
unbiased
untreated
von
vwf
willebrand
Tagcloud (Difference)
?
18k
amphiregulin
atf3
biomarker
biomarkers
bleomycin
candidate
chemotherapy
cisplatin
clustered
damage
endothelial
equalled
etoposide
gdf
hmec
hscrp
mellitus
micro
microarrays
preclinical
qrt
sets
testicular
unbiased
untreated
von
vwf
willebrand
Tagcloud (Intersection)
?