UBQLN4 and C11orf49

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UBQLN4	C11orf49
Gene Name		ubiquilin 4	chromosome 11 open reading frame 49
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Nuclear Proteasome Complex Cytosolic Proteasome Complex Perinuclear Region Of Cytoplasm	Nucleoplasm
	Molecular Function	Protein Binding Polyubiquitin Binding Identical Protein Binding
	Biological Process	Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	D-dimer levels ( 21502573)
Protein-Protein Interactions		157 interactors: ADAM33 ADPGK AGR2 ANKRD13D AREG ARL4C ATPIF1 ATXN1 BAG6 BPIFA1 C11orf49 C1orf94 C1QTNF1 CACNA1G CCDC107 CCDC134 CCDC136 CCDC14 CCDC33 CCL21 CD99 CDSN CEND1 COL8A1 COPB1 CPSF6 CRIPT CSTF2 CSTF2T CTSB CYB5R1 DAZAP2 DKK3 DMPK DNAJB11 DTX2 EAPP EDN1 EEF1A1 EFEMP2 ELF5 EPDR1 ERP27 ERP29 FA2H FGFBP1 FKBP2 FKBP7 FZD7 GABRD GDI1 GKAP1 GPX7 HAVCR1 HGS HK2 HSPA13 HSPA5 IGFBP6 IGHM IGLC1 IMMT IMPDH2 ITPRIPL1 KLHL26 KLHL42 LAT2 MDK MDM2 MIEF2 MIF4GD MLLT6 MOAP1 MYDGF NAE1 NME3 NOMO1 NOMO3 NOTCH2NL NPHP1 NPPA NXF1 OAT ORC5 PBXIP1 PCDH17 PCDH8 PDIA5 PDLIM7 PELI2 PICK1 PIN1 PIP4K2B PLA2G16 PMEPA1 PNMA1 PPIB PPIC PRL PRPF40A PSMD4 PTN PTPRN PTPRN2 QSOX1 RAD23A RAI2 RBM10 RIC8A RNF11 RNPS1 ROBO2 RPN1 RSRC2 RUNX1T1 RXRA SCAF1 SCG2 SCG5 SCMH1 SEMG1 SERPINE1 SERPINH1 SERPINI2 SMAD3 SMAD9 SMARCB1 SPAG8 SPINT1 SPP1 SRGN SRSF2 STAM2 STMN1 SUPT20H TFF1 TGFB1I1 TNFRSF14 TNRC6B TRAF2 TRIB2 TRIM32 UBQLN1 UBQLN2 UBR7 UNC119 UROS USMG5 VIP WAC YWHAQ ZBTB22 ZDHHC3 ZFPM2 ZG16 ZG16B ZNF205	12 interactors: ARHGEF15 CDC16 GSR PNMA5 PSMA1 RAB17 RAB29 RBM48 RPL8 RPS3A UBE3A UBQLN4
Entrez ID		56893	79096
HPRD ID		05670	08332
Ensembl ID		ENSG00000160803	ENSG00000149179
Uniprot IDs		B4DZF6 Q9NRR5	B4DUV7 Q9H6J7
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Process Response To Stress Positive Regulation Of Cellular Metabolic Process Response To Stimulus Signaling Signal Transduction Cell Communication Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Response To Stimulus Multicellular Organismal Development Positive Regulation Of Metabolic Process Regulation Of Cell Death Regulation Of Apoptotic Process Regulation Of Cell Proliferation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transport Organ Development Positive Regulation Of Mitochondrion Organization Regulation Of Cellular Localization Regulation Of Proteolysis Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Developmental Process Response To Organic Substance Tissue Development Regulation Of Metabolic Process Positive Regulation Of Gene Expression Anatomical Structure Development Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Signal Transduction Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Behavior Regulation Of Phosphorus Metabolic Process System Development Protein Peptidyl-prolyl Isomerization Regulation Of Signaling Negative Regulation Of Cell Proliferation Regulation Of Body Fluid Levels Regulation Of Chemotaxis Cell Surface Receptor Signaling Pathway Regulation Of Phosphorylation Cellular Localization Defense Response Regulation Of Mitochondrion Organization Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Cellular Component Organization	Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein Polyubiquitination Viral Process Regulation Of Protein Ubiquitination Regulation Of Proteolysis Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Rab Protein Signal Transduction Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Cellular Pigmentation Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Sperm Entry Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Synapse Organization Regulation Of Ubiquitin-protein Transferase Activity Catabolic Process Viral Transcription Regulation Of Synapse Structure Or Activity Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Negative Regulation Of Synapse Maturation Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Cotranslational Protein Targeting To Membrane Protein Targeting To ER Negative Regulation Of Protein Ubiquitination Establishment Of Protein Localization To Endoplasmic Reticulum Pigmentation Ubiquitin-dependent Protein Catabolic Process Retrograde Transport, Plasma Membrane To Golgi Modification-dependent Protein Catabolic Process Protein Localization To Endoplasmic Reticulum Positive Regulation Of Protein Ubiquitination Proteolysis Involved In Cellular Protein Catabolic Process Immunoglobulin Transcytosis In Epithelial Cells Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Translational Termination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Protein Ubiquitination Nuclear-transcribed MRNA Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process MRNA Catabolic Process Protein Modification By Small Protein Conjugation Protein Catabolic Process
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