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UBQLN4 and PRL
Number of citations of the paper that reports this interaction (PMID
11162551
)
3
Data Source:
BioGRID
(two hybrid)
UBQLN4
PRL
Gene Name
ubiquilin 4
prolactin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Nuclear Proteasome Complex
Cytosolic Proteasome Complex
Perinuclear Region Of Cytoplasm
Extracellular Region
Molecular Function
Protein Binding
Polyubiquitin Binding
Identical Protein Binding
Prolactin Receptor Binding
Hormone Activity
Protein Binding
Biological Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cell Surface Receptor Signaling Pathway
Female Pregnancy
Lactation
Cell Proliferation
Regulation Of Multicellular Organism Growth
Positive Regulation Of JAK-STAT Cascade
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Pathways
Amyloids
Nuclear signaling by ERBB4
Cytokine Signaling in Immune system
Signaling by ERBB4
Prolactin receptor signaling
Growth hormone receptor signaling
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Paget's disease (
21623375
)
Pulmonary function (interaction) (
23284291
)
Protein-Protein Interactions
157 interactors:
ADAM33
ADPGK
AGR2
ANKRD13D
AREG
ARL4C
ATPIF1
ATXN1
BAG6
BPIFA1
C11orf49
C1orf94
C1QTNF1
CACNA1G
CCDC107
CCDC134
CCDC136
CCDC14
CCDC33
CCL21
CD99
CDSN
CEND1
COL8A1
COPB1
CPSF6
CRIPT
CSTF2
CSTF2T
CTSB
CYB5R1
DAZAP2
DKK3
DMPK
DNAJB11
DTX2
EAPP
EDN1
EEF1A1
EFEMP2
ELF5
EPDR1
ERP27
ERP29
FA2H
FGFBP1
FKBP2
FKBP7
FZD7
GABRD
GDI1
GKAP1
GPX7
HAVCR1
HGS
HK2
HSPA13
HSPA5
IGFBP6
IGHM
IGLC1
IMMT
IMPDH2
ITPRIPL1
KLHL26
KLHL42
LAT2
MDK
MDM2
MIEF2
MIF4GD
MLLT6
MOAP1
MYDGF
NAE1
NME3
NOMO1
NOMO3
NOTCH2NL
NPHP1
NPPA
NXF1
OAT
ORC5
PBXIP1
PCDH17
PCDH8
PDIA5
PDLIM7
PELI2
PICK1
PIN1
PIP4K2B
PLA2G16
PMEPA1
PNMA1
PPIB
PPIC
PRL
PRPF40A
PSMD4
PTN
PTPRN
PTPRN2
QSOX1
RAD23A
RAI2
RBM10
RIC8A
RNF11
RNPS1
ROBO2
RPN1
RSRC2
RUNX1T1
RXRA
SCAF1
SCG2
SCG5
SCMH1
SEMG1
SERPINE1
SERPINH1
SERPINI2
SMAD3
SMAD9
SMARCB1
SPAG8
SPINT1
SPP1
SRGN
SRSF2
STAM2
STMN1
SUPT20H
TFF1
TGFB1I1
TNFRSF14
TNRC6B
TRAF2
TRIB2
TRIM32
UBQLN1
UBQLN2
UBR7
UNC119
UROS
USMG5
VIP
WAC
YWHAQ
ZBTB22
ZDHHC3
ZFPM2
ZG16
ZG16B
ZNF205
3 interactors:
PPIB
PRLR
UBQLN4
Entrez ID
56893
5617
HPRD ID
05670
07180
Ensembl ID
ENSG00000160803
ENSG00000172179
Uniprot IDs
B4DZF6
Q9NRR5
P01236
Q5THQ0
PDB IDs
1RW5
2Q98
3D48
3EW3
3MZG
3N06
3N0P
3NCB
3NCC
3NCE
3NCF
3NPZ
Enriched GO Terms of Interacting Partners
?
Regulation Of Cellular Process
Response To Stress
Positive Regulation Of Cellular Metabolic Process
Response To Stimulus
Signaling
Signal Transduction
Cell Communication
Regulation Of Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Stimulus
Multicellular Organismal Development
Positive Regulation Of Metabolic Process
Regulation Of Cell Death
Regulation Of Apoptotic Process
Regulation Of Cell Proliferation
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Transport
Organ Development
Positive Regulation Of Mitochondrion Organization
Regulation Of Cellular Localization
Regulation Of Proteolysis
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Developmental Process
Response To Organic Substance
Tissue Development
Regulation Of Metabolic Process
Positive Regulation Of Gene Expression
Anatomical Structure Development
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Catabolic Process
Regulation Of Signal Transduction
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Behavior
Regulation Of Phosphorus Metabolic Process
System Development
Protein Peptidyl-prolyl Isomerization
Regulation Of Signaling
Negative Regulation Of Cell Proliferation
Regulation Of Body Fluid Levels
Regulation Of Chemotaxis
Cell Surface Receptor Signaling Pathway
Regulation Of Phosphorylation
Cellular Localization
Defense Response
Regulation Of Mitochondrion Organization
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Cellular Component Organization
Activation Of JAK2 Kinase Activity
Prolactin Signaling Pathway
Positive Regulation By Host Of Viral Genome Replication
Positive Regulation By Host Of Viral Process
Activation Of Janus Kinase Activity
Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity
Prostate Gland Growth
Mammary Gland Epithelial Cell Differentiation
Positive Regulation Of Viral Genome Replication
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Growth Hormone Receptor Signaling Pathway
Cellular Response To Growth Hormone Stimulus
Interaction With Symbiont
Peptidyl-amino Acid Modification
Response To Growth Hormone
Mammary Gland Alveolus Development
Mammary Gland Lobule Development
Tagcloud
?
adulthood
already
autocrine
cloned
gh
hyperplasia
islet
islets
lactogen
man
mitotic
motifs
mutational
neogenesis
pancreas
pl
place
placental
preadipocyte
pref
pregnancy
prolactin
pronounced
putative
rodents
stat1
stat5
take
ways
Tagcloud (Difference)
?
adulthood
already
autocrine
cloned
gh
hyperplasia
islet
islets
lactogen
man
mitotic
motifs
mutational
neogenesis
pancreas
pl
place
placental
preadipocyte
pref
pregnancy
prolactin
pronounced
putative
rodents
stat1
stat5
take
ways
Tagcloud (Intersection)
?