Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
UBQLN4 and IMPDH2
Number of citations of the paper that reports this interaction (PMID
16713569
)
214
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
UBQLN4
IMPDH2
Gene Name
ubiquilin 4
IMP (inosine 5-monophosphate) dehydrogenase 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Nuclear Proteasome Complex
Cytosolic Proteasome Complex
Perinuclear Region Of Cytoplasm
Nucleus
Cytoplasm
Peroxisomal Membrane
Cytosol
Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Polyubiquitin Binding
Identical Protein Binding
Nucleotide Binding
DNA Binding
RNA Binding
IMP Dehydrogenase Activity
Metal Ion Binding
Biological Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Purine Nucleobase Metabolic Process
GMP Biosynthetic Process
Purine Ribonucleoside Monophosphate Biosynthetic Process
Small Molecule Metabolic Process
Lymphocyte Proliferation
Protein Homotetramerization
Nucleobase-containing Small Molecule Metabolic Process
Oxidation-reduction Process
Retina Development In Camera-type Eye
Cellular Response To Interleukin-4
Pathways
Purine ribonucleoside monophosphate biosynthesis
Purine metabolism
Metabolism of nucleotides
Drugs
NADH
Mycophenolate mofetil
Mycophenolic acid
Ribavirin Monophosphate
Nicotinamide-Adenine-Dinucleotide
Selenazole-4-Carboxyamide-Adenine Dinucleotide
6-Chloropurine Riboside, 5\'-Monophosphate
Inosinic Acid
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
157 interactors:
ADAM33
ADPGK
AGR2
ANKRD13D
AREG
ARL4C
ATPIF1
ATXN1
BAG6
BPIFA1
C11orf49
C1orf94
C1QTNF1
CACNA1G
CCDC107
CCDC134
CCDC136
CCDC14
CCDC33
CCL21
CD99
CDSN
CEND1
COL8A1
COPB1
CPSF6
CRIPT
CSTF2
CSTF2T
CTSB
CYB5R1
DAZAP2
DKK3
DMPK
DNAJB11
DTX2
EAPP
EDN1
EEF1A1
EFEMP2
ELF5
EPDR1
ERP27
ERP29
FA2H
FGFBP1
FKBP2
FKBP7
FZD7
GABRD
GDI1
GKAP1
GPX7
HAVCR1
HGS
HK2
HSPA13
HSPA5
IGFBP6
IGHM
IGLC1
IMMT
IMPDH2
ITPRIPL1
KLHL26
KLHL42
LAT2
MDK
MDM2
MIEF2
MIF4GD
MLLT6
MOAP1
MYDGF
NAE1
NME3
NOMO1
NOMO3
NOTCH2NL
NPHP1
NPPA
NXF1
OAT
ORC5
PBXIP1
PCDH17
PCDH8
PDIA5
PDLIM7
PELI2
PICK1
PIN1
PIP4K2B
PLA2G16
PMEPA1
PNMA1
PPIB
PPIC
PRL
PRPF40A
PSMD4
PTN
PTPRN
PTPRN2
QSOX1
RAD23A
RAI2
RBM10
RIC8A
RNF11
RNPS1
ROBO2
RPN1
RSRC2
RUNX1T1
RXRA
SCAF1
SCG2
SCG5
SCMH1
SEMG1
SERPINE1
SERPINH1
SERPINI2
SMAD3
SMAD9
SMARCB1
SPAG8
SPINT1
SPP1
SRGN
SRSF2
STAM2
STMN1
SUPT20H
TFF1
TGFB1I1
TNFRSF14
TNRC6B
TRAF2
TRIB2
TRIM32
UBQLN1
UBQLN2
UBR7
UNC119
UROS
USMG5
VIP
WAC
YWHAQ
ZBTB22
ZDHHC3
ZFPM2
ZG16
ZG16B
ZNF205
6 interactors:
AKT1
APIP
PIAS4
RSG1
SUMO4
UBQLN4
Entrez ID
56893
3615
HPRD ID
05670
00895
Ensembl ID
ENSG00000160803
ENSG00000178035
Uniprot IDs
B4DZF6
Q9NRR5
P12268
PDB IDs
1B3O
1NF7
1NFB
Enriched GO Terms of Interacting Partners
?
Regulation Of Cellular Process
Response To Stress
Positive Regulation Of Cellular Metabolic Process
Response To Stimulus
Signaling
Signal Transduction
Cell Communication
Regulation Of Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Stimulus
Multicellular Organismal Development
Positive Regulation Of Metabolic Process
Regulation Of Cell Death
Regulation Of Apoptotic Process
Regulation Of Cell Proliferation
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Transport
Organ Development
Positive Regulation Of Mitochondrion Organization
Regulation Of Cellular Localization
Regulation Of Proteolysis
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Developmental Process
Response To Organic Substance
Tissue Development
Regulation Of Metabolic Process
Positive Regulation Of Gene Expression
Anatomical Structure Development
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Catabolic Process
Regulation Of Signal Transduction
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Behavior
Regulation Of Phosphorus Metabolic Process
System Development
Protein Peptidyl-prolyl Isomerization
Regulation Of Signaling
Negative Regulation Of Cell Proliferation
Regulation Of Body Fluid Levels
Regulation Of Chemotaxis
Cell Surface Receptor Signaling Pathway
Regulation Of Phosphorylation
Cellular Localization
Defense Response
Regulation Of Mitochondrion Organization
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Cellular Component Organization
Protein Sumoylation
Glycogen Cell Differentiation Involved In Embryonic Placenta Development
Protein Modification By Small Protein Conjugation
Positive Regulation Of Keratinocyte Apoptotic Process
L-methionine Biosynthetic Process From S-adenosylmethionine
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport
Negative Regulation Of Fatty Acid Beta-oxidation
Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Apoptotic Signaling Pathway
Peptidyl-amino Acid Modification
S-adenosylmethionine Cycle
Response To UV-A
Activation-induced Cell Death Of T Cells
Peptidyl-lysine Modification
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
L-methionine Biosynthetic Process From Methylthioadenosine
L-methionine Salvage
Negative Regulation Of Fatty Acid Oxidation
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Protein Sumoylation
Positive Regulation Of Glycogen Biosynthetic Process
Nitric Oxide Biosynthetic Process
Regulation Of Protein Catabolic Process
Negative Regulation Of Cell Size
Regulation Of Apoptotic Process
Methionine Biosynthetic Process
Spongiotrophoblast Layer Development
Negative Regulation Of Release Of Cytochrome C From Mitochondria
S-adenosylmethionine Metabolic Process
T Cell Apoptotic Process
Regulation Of Fatty Acid Beta-oxidation
Positive Regulation Of Nitric-oxide Synthase Activity
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Cell Death
Methionine Metabolic Process
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Protein Sumoylation
Insulin-like Growth Factor Receptor Signaling Pathway
Sulfur Amino Acid Biosynthetic Process
Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Peripheral Nervous System Myelin Maintenance
Response To Food
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Mammary Gland Epithelial Cell Differentiation
Negative Regulation Of Fatty Acid Metabolic Process
Negative Regulation Of Lipid Transport
Tagcloud
?
biogenesis
biosynthesis
dehydrogenase
deoxy
disrupts
dually
genotoxic
gtp
guanine
inauzhin
inosine
inz
mdm2
monophosphate
notion
nucleostemin
pools
ribonucleotide
ribosomal
rpl11
rpl5
rps
rrna
rs
sirt1
stressor
suppresses
surprisingly
Tagcloud (Difference)
?
biogenesis
biosynthesis
dehydrogenase
deoxy
disrupts
dually
genotoxic
gtp
guanine
inauzhin
inosine
inz
mdm2
monophosphate
notion
nucleostemin
pools
ribonucleotide
ribosomal
rpl11
rpl5
rps
rrna
rs
sirt1
stressor
suppresses
surprisingly
Tagcloud (Intersection)
?