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DIABLO and AGTRAP
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
DIABLO
AGTRAP
Description
diablo IAP-binding mitochondrial protein
angiotensin II receptor associated protein
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Mitochondrion
Mitochondrial Intermembrane Space
Cytosol
Cytoplasmic Side Of Plasma Membrane
CD40 Receptor Complex
Golgi Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Plasma Membrane
Cell Cortex
Membrane
Cytoplasmic Vesicle Membrane
Cytoplasmic Vesicle
Molecular Function
Protein Binding
Angiotensin Type II Receptor Activity
Protein Binding
Identical Protein Binding
Biological Process
Apoptotic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress
Positive Regulation Of Apoptotic Process
Neuron Apoptotic Process
Apoptotic Signaling Pathway
Intrinsic Apoptotic Signaling Pathway
Response To Hypoxia
Regulation Of Blood Pressure
Angiotensin-activated Signaling Pathway
Pathways
Release of apoptotic factors from the mitochondria
SMAC (DIABLO) binds to IAPs
SMAC (DIABLO) binds to IAPs
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
SMAC, XIAP-regulated apoptotic response
Regulation of the apoptosome activity
Signaling by BRAF and RAF1 fusions
Drugs
Phenethyl Isothiocyanate
Diseases
GWAS
A body shape index (
34021172
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Arterial stiffness (brachial-femoral pulse wave velocity) (
32790701
)
Basophil percentage of white cells (
32888494
)
Systolic blood pressure (
19430483
)
Interacting Genes
45 interacting genes:
AGTRAP
APOC2
APOC4
AREL1
ARL6IP1
ARNT
BEX3
BIRC2
BIRC3
BIRC5
BIRC6
BIRC7
CASP9
CDC34
CMTM4
DERL2
DGAT2L6
DHRS1
E2F1
EEF1A1
FADS6
FKBP7
HSD17B13
HSFX1
HTRA2
LTBR
MAML2
MICOS13
MPC2
NR4A1
RHBDD2
RMDN2
SEC22A
SFT2D1
SLC17A9
SLC25A47
SLC66A2
STMN4
SYP
TIMMDC1
UBC
UBE2K
UFM1
XIAP
ZNF746
138 interacting genes:
ACSF2
AGTR1
AGTR2
ALDH18A1
ANKS6
AP3M1
APOA4
AQP6
ARAF
ARFIP2
ARHGAP1
ATP5F1E
BCL2L13
BPIFA2
CAPNS1
CCDC70
CD160
CD79A
CELA3A
CIAO2A
COQ8A
CPLX1
CPLX4
CRCT1
CYB5R3
CYBC1
DDA1
DDX55
DGCR6
DIABLO
DNAJC1
ECPAS
ERGIC3
ETFRF1
FAM114A1
FAM209A
FARS2
FASTKD3
FATE1
FFAR2
FGA
FHIP1B
FNDC9
GABARAPL2
GAD1
GAD2
GDNF
GPR152
GPX8
GTF2H1
GTF3C1
H4C7
HARS2
HIBADH
HMGB1
HSBP1L1
HSCB
HSD17B13
HSFX1
HSFX2
HSPA4
IL7R
ISCU
KCNK5
KIR2DL3
KIR3DL3
LMNA
LMO2
LNX1
LRRC4C
LRRC59
MCEE
MGST3
MIEF1
MIEF2
MMD
MRM1
MRPL11
MRRF
MTERF3
MUTYH
MYG1
NDRG4
NDUFAF3
NFU1
NFYB
NKG7
PBX3
PCTP
PCYT1A
PDHX
PIMREG
PITPNC1
PNPO
POLDIP2
PPIF
PRPF18
PTPN9
RAB30
RACK1
RBFA
RETREG3
RMDN2
S100B
SCAND1
SENP2
SH3GLB1
SLC18A1
SLC7A14
SMG9
SNX1
SPG21
SSX3
SSX5
STAG3L1
STAR
STARD4
STMN4
STX1A
SUCLA2
SYT16
TBRG4
TCEA2
TCEANC2
TFAM
THAP4
TMEM139
TMEM14B
TMEM31
TMPPE
TPD52L3
TTPA
TUBA1B
TXN2
UBE2I
YARS2
ZFYVE21
ZNF391
Entrez ID
56616
57085
HPRD ID
05560
16379
Ensembl ID
ENSG00000184047
ENSG00000177674
Uniprot IDs
A0A0S2Z5P6
A0A0S2Z5U7
K7X1S0
Q502X2
Q9NR28
Q6RW13
PDB IDs
1FEW
1G3F
1G73
1OXQ
1TW6
1XB0
1XB1
3D9U
3UIH
3UIJ
4TX5
6JX6
8ATO
8AUW
8E2I
8E2J
Enriched GO Terms of Interacting Partners
?
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Cell Death
Apoptotic Process
Programmed Cell Death
Ubiquitin-protein Transferase Activity
Cysteine-type Endopeptidase Inhibitor Activity
Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Post-translational Protein Modification
Regulation Of Post-translational Protein Modification
Cellular Response To Interferon-beta
Macromolecule Catabolic Process
Negative Regulation Of Apoptotic Process
Protein Modification By Small Protein Conjugation
Ubiquitin Conjugating Enzyme Activity
Negative Regulation Of Programmed Cell Death
Response To Interferon-beta
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Ubiquitination
Protein Ubiquitination
Signal Recognition Particle Binding
Peptidase Inhibitor Activity
Post-translational Protein Modification
Ubiquitin Protein Ligase Activity
CD40 Receptor Complex
Proteolysis Involved In Protein Catabolic Process
Positive Regulation Of Protein Modification Process
Identical Protein Binding
Canonical NF-kappaB Signal Transduction
Organophosphate Ester Transport
Regulation Of Inflammatory Response
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Protein Polyubiquitination
Proteolysis
Positive Regulation Of Protein Polyubiquitination
Response To Hypoxia
Negative Regulation Of Necroptotic Process
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Protein Catabolic Process
Regulation Of RIG-I Signaling Pathway
Very-low-density Lipoprotein Particle
Negative Regulation Of Programmed Necrotic Cell Death
Response To Decreased Oxygen Levels
Protein Binding
Positive Regulation Of Execution Phase Of Apoptosis
Regulation Of Protein Modification Process
Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway
Regulation Of Canonical NF-kappaB Signal Transduction
Nucleotide Transmembrane Transport
Mitochondrial Matrix
Mitochondrion
Protein Binding
Lipid Binding
Succinate Metabolic Process
Gamma-aminobutyrate Shunt
Glutamate Decarboxylase Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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