DIABLO and BIRC7

Number of citations of the paper that reports this interaction (PMID 11801603)
18

Data Source:
HPRD (in vitro, in vivo)

		DIABLO	BIRC7
Gene Name		diablo, IAP-binding mitochondrial protein	baculoviral IAP repeat containing 7
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Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex	Nucleus Cytoplasm Golgi Apparatus Spindle Microtubule
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Zinc Ion Binding Ligase Activity Enzyme Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Positive Regulation Of Apoptotic Process Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway	Activation Of JUN Kinase Activity Regulation Of Signal Transduction Protein Ubiquitination Regulation Of Cell Proliferation Negative Regulation Of Apoptotic Process Regulation Of Natural Killer Cell Apoptotic Process Mitotic Spindle Assembly Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Pathways		Release of apoptotic factors from the mitochondria Apoptotic factor-mediated response SMAC binds to IAPs Programmed Cell Death SMAC-mediated dissociation of IAP:caspase complexes SMAC-mediated apoptotic response Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: AREL1 ARL6IP1 ARNT BIRC2 BIRC3 BIRC5 BIRC6 BIRC7 CASP9 EEF1A1 HTRA2 LTBR MAML2 NGFRAP1 NR4A1 SLC25A47 UBE2K UFM1 XIAP ZNF746	18 interactors: AES BIRC2 CASP3 CASP7 CASP9 DDX6 DIABLO FAM124B HTRA2 PHF1 POLR1C UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2I UBE2K
Entrez ID		56616	79444
HPRD ID		05560	05761
Ensembl ID		ENSG00000184047	ENSG00000101197
Uniprot IDs		K7X1S0 Q502X2 Q9NR28	Q96CA5
PDB IDs		1FEW 1G3F 1G73 1TW6 1XB0 1XB1 3D9U 3UIH 3UIJ	1OXN 1OXQ 1OY7 1TW6 2I3H 2I3I 3F7G 3F7H 3F7I 3GT9 3GTA 3UW5 4AUQ
Enriched GO Terms of Interacting Partners?		Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Regulation Of Proteolysis Regulation Of Cell Death Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Apoptotic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Proteolysis Protein Ubiquitination Negative Regulation Of Protein Processing Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Protein Metabolic Process Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Negative Regulation Of Cell Death Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Cell Death Apoptotic Signaling Pathway Regulation Of Metabolic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Necroptotic Process Positive Regulation Of Signal Transduction Negative Regulation Of Necrotic Cell Death Regulation Of RIG-I Signaling Pathway Regulation Of Necroptotic Process Regulation Of Signaling Intracellular Signal Transduction Protein Metabolic Process Regulation Of Neuron Death	Cellular Macromolecule Catabolic Process Regulation Of Proteolysis Positive Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Protein Polyubiquitination Proteolysis Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Apoptotic Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Intrinsic Apoptotic Signaling Pathway Protein Ubiquitination Toll-like Receptor 4 Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Modification By Small Protein Conjugation Catabolic Process Regulation Of Cysteine-type Endopeptidase Activity Apoptotic Process Programmed Cell Death Protein Processing Regulation Of Cellular Protein Metabolic Process Cell Death Death Toll-like Receptor Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Stress Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Regulation Of Protein Metabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Peptidase Activity Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Metabolic Process
Tagcloud ?		angiogen angioprevention argeting attributes b2g2 ccm cdc2 cdc25c cdks conditioned esis gallate grape hallmarks hile howed hpmecs huvecs invasiveness ngioprevention normoxic o2 pc3 phytochemicals procyanidin smac tube vegfr2 warrants	actg1 alteration chrcc chromophobe cpq distinctions ectopic enabled exome faah2 fusions met mitf mutated nccrccs nf2 oncocytoma oncocytomas papillary pdhb pdxdc1 pnkd prcc rcc slc5a3 transcriptome trcc unreported znf765
Tagcloud (Difference) ?		angiogen angioprevention argeting attributes b2g2 ccm cdc2 cdc25c cdks conditioned esis gallate grape hallmarks hile howed hpmecs huvecs invasiveness ngioprevention normoxic o2 pc3 phytochemicals procyanidin smac tube vegfr2 warrants	actg1 alteration chrcc chromophobe cpq distinctions ectopic enabled exome faah2 fusions met mitf mutated nccrccs nf2 oncocytoma oncocytomas papillary pdhb pdxdc1 pnkd prcc rcc slc5a3 transcriptome trcc unreported znf765
Tagcloud (Intersection) ?