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DIABLO
Gene Name
diablo, IAP-binding mitochondrial protein
Image
Gene Ontology Annotations
Cellular Component
Mitochondrion
Mitochondrial Intermembrane Space
Cytosol
Cytoplasmic Side Of Plasma Membrane
CD40 Receptor Complex
Molecular Function
Protein Binding
Biological Process
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C
Positive Regulation Of Apoptotic Process
Neuron Apoptotic Process
Intrinsic Apoptotic Signaling Pathway
Pathways
Release of apoptotic factors from the mitochondria
Apoptotic factor-mediated response
SMAC binds to IAPs
Programmed Cell Death
SMAC-mediated dissociation of IAP:caspase complexes
SMAC-mediated apoptotic response
Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Protein-protein Interactions
20 interactors:
AREL1
ARL6IP1
ARNT
BIRC2
BIRC3
BIRC5
BIRC6
BIRC7
CASP9
EEF1A1
HTRA2
LTBR
MAML2
NGFRAP1
NR4A1
SLC25A47
UBE2K
UFM1
XIAP
ZNF746
Entrez ID
56616
HPRD ID
05560
Ensembl ID
ENSG00000184047
Uniprot IDs
K7X1S0
Q502X2
Q9NR28
PDB IDs
1FEW
1G3F
1G73
1TW6
1XB0
1XB1
3D9U
3UIH
3UIJ
Enriched GO Terms of Interacting Partners
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Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Regulation Of Endopeptidase Activity
Regulation Of Peptidase Activity
Regulation Of Proteolysis
Regulation Of Cell Death
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Apoptotic Process
Protein Modification By Small Protein Conjugation
Negative Regulation Of Endopeptidase Activity
Negative Regulation Of Peptidase Activity
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Proteolysis
Protein Ubiquitination
Negative Regulation Of Protein Processing
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Protein Metabolic Process
Negative Regulation Of Hydrolase Activity
Regulation Of Protein Processing
Negative Regulation Of Cell Death
Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Catalytic Activity
Negative Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Protein Metabolic Process
Regulation Of Catalytic Activity
Positive Regulation Of Cell Death
Apoptotic Signaling Pathway
Regulation Of Metabolic Process
Intrinsic Apoptotic Signaling Pathway
Regulation Of Signal Transduction
Negative Regulation Of Necroptotic Process
Positive Regulation Of Signal Transduction
Negative Regulation Of Necrotic Cell Death
Regulation Of RIG-I Signaling Pathway
Regulation Of Necroptotic Process
Regulation Of Signaling
Intracellular Signal Transduction
Protein Metabolic Process
Regulation Of Neuron Death
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angiogen
angioprevention
argeting
attributes
b2g2
ccm
cdc2
cdc25c
cdks
conditioned
esis
gallate
grape
hallmarks
hile
howed
hpmecs
huvecs
invasiveness
ngioprevention
normoxic
o2
pc3
phytochemicals
procyanidin
smac
tube
vegfr2
warrants