FANCL and RIMBP3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FANCL	RIMBP3
Gene Name		Fanconi anemia, complementation group L	RIMS binding protein 3
Image
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Nucleoplasm Cytoplasm Fanconi Anaemia Nuclear Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Gamete Generation Regulation Of Cell Proliferation
Pathways		Fanconi Anemia pathway
Drugs
Diseases
GWAS		Body mass index ( 20935630) Obesity ( 23563607)	Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		24 interactors: ACVR1 BMPR1B C17orf70 CCDC36 CHCHD3 DOCK8 EIF4ENIF1 FANCB FANCD2 FANCI GGN GRN HES1 IKZF3 KIFC3 LZTS2 PCNA RBM45 RIMBP3 SSX2IP TFCP2 TGFBR1 UBE2T UBE2W	18 interactors: AES AQP1 ARNT2 CATSPER1 CREB5 CTBP2 DGCR6 DGCR6L DTX2 FANCL MVP NOXA1 POLR1C PPIL1 PRKAA1 PRKAB2 TRAF3IP2 ZNF488
Entrez ID		55120	85376
HPRD ID		06997	13881
Ensembl ID		ENSG00000115392	ENSG00000196622
Uniprot IDs		B5MC31 B5MCZ6 Q9NW38	Q9UFD9
PDB IDs		3ZQS	2EGE
Enriched GO Terms of Interacting Partners?		Pharyngeal System Development DNA Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Single Organism Reproductive Process Pathway-restricted SMAD Protein Phosphorylation Response To Stress Reproductive Process Mesenchymal Cell Development Protein K11-linked Ubiquitination Epithelial Cell Fate Commitment Gamete Generation Mesenchymal Cell Differentiation Movement Of Cell Or Subcellular Component Activin Receptor Signaling Pathway Cellular Response To Stress Urogenital System Development Cellular Response To Stimulus Sexual Reproduction Multicellular Organismal Reproductive Process Positive Regulation Of Bone Mineralization Protein Monoubiquitination Positive Regulation Of Biomineral Tissue Development Multicellular Organism Reproduction Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Pattern Specification Process Mesenchyme Development Regulation Of Transcription From RNA Polymerase II Promoter Peptidyl-threonine Phosphorylation In Utero Embryonic Development Nucleobase-containing Compound Metabolic Process Negative Regulation Of Stomach Neuroendocrine Cell Differentiation Negative Regulation Of Pancreatic A Cell Differentiation Positive Regulation Of Deoxyribonuclease Activity Pharyngeal Arch Artery Morphogenesis Memory T Cell Proliferation Lateral Inhibition Endocardial Cushion Cell Fate Commitment Cell Cycle Heart Morphogenesis Heart Development Smooth Muscle Cell Differentiation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Artery Morphogenesis Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cardiac Septum Morphogenesis Thymus Development Stem Cell Development Heterocycle Metabolic Process See more	Nucleobase-containing Compound Metabolic Process Ammonium Transmembrane Transport Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation RNA Metabolic Process Cellular Response To Hydrogen Peroxide Response To Hypoxia Ammonium Transport Gene Expression Carbon Dioxide Transmembrane Transport Corticotropin Secretion Establishment Or Maintenance Of Actin Cytoskeleton Polarity Nitrogen Compound Metabolic Process Metanephric Proximal Convoluted Tubule Development Nitric Oxide Transport Negative Regulation Of Glucose Import In Response To Insulin Stimulus Cellular Response To Mercury Ion Cellular Response To Hypoxia Negative Regulation Of Cellular Metabolic Process Cellular Response To Decreased Oxygen Levels Cellular Response To Reactive Oxygen Species Biosynthetic Process Response To Camptothecin Metanephric Proximal Tubule Development Positive Regulation Of Anoikis Cellular Response To Oxygen Levels Regulation Of Cell Proliferation Renal Water Absorption Positive Regulation Of Saliva Secretion Carbon Dioxide Transport Epithelial Fluid Transport Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Fat Cell Differentiation Response To Hydrogen Peroxide Response To Hormone Fatty Acid Biosynthetic Process Response To UV Cellular Response To Organonitrogen Compound Positive Regulation Of Chromatin Binding Renal Water Transport See more
Tagcloud ?		2p16 2q24 4p15 agencies assisting epilepsies epilepsy ethnically filtering generalised governmental grouping harbouring heritability ie implicating imputation league lumping pcdh7 phenotyped philanthropic pleiotropically protocadherin scn1a splitting standardised unclassified vrk2
Tagcloud (Difference) ?		2p16 2q24 4p15 agencies assisting epilepsies epilepsy ethnically filtering generalised governmental grouping harbouring heritability ie implicating imputation league lumping pcdh7 phenotyped philanthropic pleiotropically protocadherin scn1a splitting standardised unclassified vrk2
Tagcloud (Intersection) ?