PRNP and CLU

  • Number of citations of the paper that reports this interaction (PMID 15146195)
  • 32
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)
  • HPRD (in vivo)

PRNP

CLU

Gene Name prion protein clusterin
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 76 interactors: ABT1 ADAM23 ADAP2 AGO1 AIFM3 APBB1 APLP1 APLP2 APOE ARHGAP15 BAG6 BAZ2B C7orf50 CAV1 CCDC149 CIRBP CIRH1A CLSTN1 CLU CNP CNTN1 CSN3 CSNK2A1 CSNK2A2 CSNK2B CWC15 DDX47 DNM1 DPP6 DYRK3 ERI3 FAM27E3 FGF13 FHL1 GRB2 HSPA5 HSPD1 IER3 KIAA1191 L1CAM LSAMP MAG MARK4 MOG MTG1 NCAM1 NCAM2 NHP2 NOB1 OPCML P4HB PDE4DIP PLG PPFIBP2 PPP1R14A PSMA3 PTRH1 PVRL1 RBM22 RNPC3 RPL41 SCNM1 SPARCL1 STIP1 SURF2 TBPL1 TMEM237 TSC22D4 TSLP TYMSOS WDR5 WIBG ZFYVE28 ZKSCAN8 ZNF408 ZNF740 44 interactors: APP BAG6 C7 C8B C9 CBY1 CD209 CLUAP1 CYP2E1 DISC1 ELN FOS GRB2 HSPD1 IL24 KATNA1 KEAP1 KLF11 KNSTRN LEP LEPR LIG4 LRP2 LRP8 LYZ MAPK9 MDM2 MMP25 PAXIP1 POLR1C PON1 PRNP RBBP8 RPL23 SYVN1 TGFBR1 TGFBR2 TNIK TSC22D4 TTR VHL VLDLR XRCC6 ZWINT
Entrez ID 5621 1191
HPRD ID 01453 01706
Ensembl ID ENSG00000171867 ENSG00000120885
Uniprot IDs B2NI04 F7VJQ1 P04156 Q53YK7 P10909
PDB IDs 1E1G 1E1J 1E1P 1E1S 1E1U 1E1W 1FKC 1FO7 1H0L 1HJM 1HJN 1I4M 1OEH 1OEI 1QLX 1QLZ 1QM0 1QM1 1QM2 1QM3 2IV4 2IV5 2IV6 2K1D 2KUN 2LBG 2LEJ 2LFT 2LSB 2LV1 2M8T 2OL9 2W9E 3HAF 3HAK 3HEQ 3HER 3HES 3HJ5 3HJX 3MD4 3MD5 3NHC 3NHD 3NVF 4DGI 4E1H 4E1I
Enriched GO Terms of Interacting Partners?
Tagcloud ?
chelation  cooperatively  copper  cysteines  excitotoxicity  exert  favor  glun1  glun2a  glutamatergic  hippocampi  indeed  innovation  insults  interdependent  modulates  mounting  neurodegeneration  neuroprotection  nitric  nitrosylation  nmdar  organotypic  oxide  prion  prnp0  prpc  synapses  thiols 
allometric  allometry  amphotericin  bolus  cmin  contributions  cpeak  disposition  hplc  humans  insignificant  inspite  interspecies  mrt  parameter  perform  pharmacokinetic  pharmacokinetics  predictions  preliminary  rabbits  rationalized  scaling  t0  triexponential  vdarea  vss  vuss 
Tagcloud (Difference) ?
chelation  cooperatively  copper  cysteines  excitotoxicity  exert  favor  glun1  glun2a  glutamatergic  hippocampi  indeed  innovation  insults  interdependent  modulates  mounting  neurodegeneration  neuroprotection  nitric  nitrosylation  nmdar  organotypic  oxide  prion  prnp0  prpc  synapses  thiols 
allometric  allometry  amphotericin  bolus  cmin  contributions  cpeak  disposition  hplc  humans  insignificant  inspite  interspecies  mrt  parameter  perform  pharmacokinetic  pharmacokinetics  predictions  preliminary  rabbits  rationalized  scaling  t0  triexponential  vdarea  vss  vuss 
Tagcloud (Intersection) ?