LAMB1 and ATXN7L2

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LAMB1	ATXN7L2
Gene Name		laminin, beta 1	ataxin 7-like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-1 Complex Laminin-2 Complex Extracellular Space Extracellular Matrix Laminin-8 Complex Laminin-10 Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent Enzyme Binding Glycosphingolipid Binding
	Biological Process	Cell Adhesion Negative Regulation Of Cell Adhesion Axon Guidance Embryo Implantation Neuronal-glial Interaction Involved In Cerebral Cortex Radial Glia Guided Migration Extracellular Matrix Disassembly Extracellular Matrix Organization Positive Regulation Of Cell Migration Neuron Projection Development Substrate Adhesion-dependent Cell Spreading Endodermal Cell Differentiation Odontogenesis Positive Regulation Of Epithelial Cell Proliferation
Pathways		Axon guidance Laminin interactions ECM proteoglycans L1CAM interactions Non-integrin membrane-ECM interactions Degradation of the extracellular matrix
Drugs
Diseases
GWAS		IgG glycosylation ( 23382691) Ulcerative colitis ( 19915572 20228799 19122664)	Chronic kidney disease ( 20383146) Major depressive disorder ( 20125088)
Protein-Protein Interactions		10 interactors: ACHE ANTXR2 ATXN7 ATXN7L2 CACNA1A COL6A1 EIF3I ERBB2IP GFI1B TGFB1	4 interactors: CBX3 LAMB1 MDFI PPP2R3A
Entrez ID		3912	127002
HPRD ID		01029	12506
Ensembl ID		ENSG00000091136	ENSG00000162650
Uniprot IDs		P07942 Q8TAS6	I6L9B5 Q5T6C5
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Growth Neurotransmitter Metabolic Process Ossification Cellular Component Assembly Regulation Of Protein Secretion Cerebellar Molecular Layer Development Negative Regulation Of Synaptic Transmission, Cholinergic Neurotransmitter Receptor Biosynthetic Process Defense Response To Fungus, Incompatible Interaction Positive Regulation Of NAD+ ADP-ribosyltransferase Activity Synapse Assembly Receptor Metabolic Process Endoderm Development Cell Adhesion Growth Acetylcholine Catabolic Process Vestibular Nucleus Development Basal Protein Localization Active Induction Of Host Immune Response By Virus Acetylcholine Catabolic Process In Synaptic Cleft Regulation Of Histone Modification Negative Regulation Of Hyaluronan Biosynthetic Process Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Macrophage Derived Foam Cell Differentiation Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Neurotransmitter Levels Osteoblast Differentiation Regulation Of Protein Transport Regulation Of Secretion Negative Regulation Of Macrophage Cytokine Production Ossification Involved In Bone Remodeling Tolerance Induction To Self Antigen Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Exit From Mitosis Gamma-aminobutyric Acid Secretion Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization ERBB Signaling Pathway Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Receptor Biosynthetic Process Regulation Of Extracellular Matrix Assembly Positive Regulation Of Smooth Muscle Cell Differentiation Frontal Suture Morphogenesis Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Acetylcholine Secretion, Neurotransmission Synapse Organization Cell Morphogenesis Involved In Differentiation	Neuronal-glial Interaction Involved In Cerebral Cortex Radial Glia Guided Migration Organ Morphogenesis Regulation Of Cell Motility Involved In Somitogenic Axis Elongation Negative Regulation Of Wnt Signaling Pathway Embryo Development Regulation Of Wnt Signaling Pathway Regulation Of Somitogenesis Wnt Signaling Pathway Involved In Somitogenesis Somatic Muscle Development Pattern Specification Process
Tagcloud ?		acad amp analogs boylan chambon cyclic dhss dhss2 dnase electrophoretic endoderm enhancer f9 flanking gudas homeobox hypersensitive laminin lohnes maximally natl parietal proc ra taneja teratocarcinoma transcriptionally transfections ttattaaca
Tagcloud (Difference) ?		acad amp analogs boylan chambon cyclic dhss dhss2 dnase electrophoretic endoderm enhancer f9 flanking gudas homeobox hypersensitive laminin lohnes maximally natl parietal proc ra taneja teratocarcinoma transcriptionally transfections ttattaaca
Tagcloud (Intersection) ?