HSPBP1

Description		HSPA (Hsp70) binding protein 1
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GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Enzyme Inhibitor Activity Protein Binding Ubiquitin Protein Ligase Binding Molecular Sequestering Activity
	Biological Process	Protein Folding Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		14 interacting genes: APP CLK1 EFEMP2 HSPA1A HSPA1B HSPA2 HSPA4 HSPA5 HSPA8 HSPA9 KRT27 LRIF1 NOTCH2NLA PTEN
Entrez ID		23640
HPRD ID		09991
Ensembl ID		ENSG00000133265
Uniprot IDs		Q9NZL4
PDB IDs		1XQR 1XQS 8X87
Enriched GO Terms of Interacting Partners?		ATP-dependent Protein Folding Chaperone Protein Refolding Protein Folding Chaperone Heat Shock Protein Binding Protein Folding Enzyme Binding Unfolded Protein Binding C3HC4-type RING Finger Domain Binding ATP-dependent Protein Disaggregase Activity Negative Regulation Of Inclusion Body Assembly ATP Hydrolysis Activity G Protein-coupled Receptor Binding Extracellular Exosome Regulation Of Inclusion Body Assembly Response To Unfolded Protein Protein-folding Chaperone Binding Regulation Of Protein Import Blood Microparticle Ubiquitin Protein Ligase Binding ATP Binding Regulation Of Erythrocyte Differentiation Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Cellular Heat Acclimation Negative Regulation Of Cellular Component Organization Focal Adhesion Positive Regulation Of Proteolysis Nucleotide Binding Positive Regulation Of Microtubule Nucleation Cellular Response To Steroid Hormone Stimulus Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Response To Heat Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Misfolded Protein Binding Inclusion Body Regulation Of Microtubule Nucleation Ficolin-1-rich Granule Lumen Receptor Ligand Activity Chaperone-mediated Protein Complex Assembly Regulation Of Mitotic Spindle Assembly Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Protein Stability Negative Regulation Of Cell Population Proliferation Regulation Of Proteolysis Regulation Of Supramolecular Fiber Organization Response To Temperature Stimulus Regulation Of Cellular Component Organization Regulation Of Extrinsic Apoptotic Signaling Pathway
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