ARFGAP1 and RASIP1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ARFGAP1	RASIP1
Gene Name		ADP-ribosylation factor GTPase activating protein 1	Ras interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Golgi-associated Vesicle Membrane Synapse	Golgi Stack Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding ARF GTPase Activator Activity Zinc Ion Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Protein Transport Endoplasmic Reticulum Unfolded Protein Response Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity Cellular Protein Metabolic Process COPI Coating Of Golgi Vesicle Membrane Organization	Angiogenesis Vasculogenesis Signal Transduction Negative Regulation Of Autophagy Regulation Of Rho GTPase Activity Branching Morphogenesis Of An Epithelial Tube
Pathways		IRE1alpha activates chaperones COPI Mediated Transport XBP1(S) activates chaperone genes Golgi to ER Retrograde Transport Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972) Crohn's disease ( 21102463) Dietary macronutrient intake ( 23372041) Retinal vascular caliber ( 21060863)
Protein-Protein Interactions		31 interactors: APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GRN KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RASIP1 REEP5 RFC3 RGS2 RPL11 SMN1 TK1 TMED2 TRIM23	8 interactors: ARFGAP1 HRAS LDB2 MRAS RAP1A RAP2A RRAS RRAS2
Entrez ID		55738	54922
HPRD ID		06443	15214
Ensembl ID		ENSG00000101199	ENSG00000105538
Uniprot IDs		B7Z3U0 B7Z8H8 E7EV62 Q53F62 Q8N6T3	Q5U651 Q7L251 Q8IUR2
PDB IDs		3DWD 3O47
Enriched GO Terms of Interacting Partners?		Triglyceride Catabolic Process Acylglycerol Catabolic Process Vesicle-mediated Transport COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Response To Extracellular Stimulus Protein-lipid Complex Assembly Protein Transport Establishment Of Protein Localization Plasma Lipoprotein Particle Remodeling Cholesterol Efflux Cellular Component Assembly Triglyceride Metabolic Process Protein Localization Vesicle Targeting, To, From Or Within Golgi Neutral Lipid Metabolic Process Response To Nutrient Levels Cholesterol Metabolic Process Plasma Lipoprotein Particle Clearance Sterol Metabolic Process Localization Within Membrane Vesicle Targeting Autophagic Vacuole Assembly Transport Cellular Lipid Catabolic Process Autophagy Regulation Of Catalytic Activity Response To Light Stimulus Macroautophagy Triglyceride Mobilization Very-low-density Lipoprotein Particle Assembly Chylomicron Remnant Clearance Membrane Organization Regulation Of Plasma Lipoprotein Particle Levels Low-density Lipoprotein Particle Remodeling Cholesterol Transport Sterol Transport Glycerolipid Metabolic Process Negative Regulation Of Cholesterol Transport Regulation Of Signaling Phospholipid Efflux Negative Regulation Of Hydrolase Activity Endocytosis Regulation Of Protein Processing Regulation Of Proteolysis Phototransduction, Visible Light Cholesterol Homeostasis Cellular Response To Extracellular Stimulus Sterol Homeostasis	Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction Rap Protein Signal Transduction Intracellular Signal Transduction Regulation Of Cell Migration Regulation Of Phosphorylation Regulation Of ERK1 And ERK2 Cascade Regulation Of MAPK Cascade Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Component Movement Positive Regulation Of Protein Phosphorylation Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Signal Transduction Cell Differentiation Activation Of MAPKK Activity Developmental Process Regulation Of Protein Phosphorylation Signaling Positive Regulation Of Cellular Protein Metabolic Process Cell Communication Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Regulation Of Cell Projection Organization Positive Regulation Of Kinase Activity Regulation Of Ras GTPase Activity System Development Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transferase Activity Cellular Response To Stimulus Positive Regulation Of ERK1 And ERK2 Cascade Actin Cytoskeleton Organization Regulation Of Signal Transduction Actin Filament-based Process Generation Of Neurons Regulation Of Ras Protein Signal Transduction Regulation Of Cell Differentiation Multicellular Organismal Development Neurogenesis Regulation Of JNK Cascade Positive Regulation Of GTPase Activity Anatomical Structure Development Regulation Of Signaling Regulation Of Protein Kinase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Rac Protein Signal Transduction Regulation Of Stress-activated MAPK Cascade
Tagcloud ?		accelerated adaptors adp associates cargo cathepsin cation cimpr clathrin copi ear endosomes exit explaining gga ggas golgi mannose perturbed rescued retrograde ribosylation slowed sorting traffic
Tagcloud (Difference) ?		accelerated adaptors adp associates cargo cathepsin cation cimpr clathrin copi ear endosomes exit explaining gga ggas golgi mannose perturbed rescued retrograde ribosylation slowed sorting traffic
Tagcloud (Intersection) ?