ARFGAP1 and TRIM23

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ARFGAP1	TRIM23
Gene Name		ADP-ribosylation factor GTPase activating protein 1	tripartite motif containing 23
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Golgi-associated Vesicle Membrane Synapse	Golgi Membrane Nucleus Lysosomal Membrane Extracellular Vesicular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding ARF GTPase Activator Activity Zinc Ion Binding	GTPase Activity Ubiquitin-protein Transferase Activity Protein Binding GTP Binding Enzyme Activator Activity Zinc Ion Binding Ligase Activity GDP Binding Identical Protein Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Protein Transport Endoplasmic Reticulum Unfolded Protein Response Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity Cellular Protein Metabolic Process COPI Coating Of Golgi Vesicle Membrane Organization	Small GTPase Mediated Signal Transduction Viral Process Protein Ubiquitination Positive Regulation Of Catalytic Activity
Pathways		IRE1alpha activates chaperones COPI Mediated Transport XBP1(S) activates chaperone genes Golgi to ER Retrograde Transport Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		31 interactors: APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GRN KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RASIP1 REEP5 RFC3 RGS2 RPL11 SMN1 TK1 TMED2 TRIM23	137 interactors: AKTIP ANKRD36BP1 AQP1 ARFGAP1 ARHGEF3 ARNT2 ATPAF2 ATXN7 BAG1 C10orf10 C19orf57 C8orf33 CARD9 CCDC146 CCDC25 CDC20B CDR2 CFAP53 COX5B CREB5 CXCL14 CYTH1 CYTH2 DCX DMC1 DMRT3 DOCK2 EAF2 EXOC3-AS1 FAM103A1 FAM110A FAM133A FAM193B FAM208B FAM83A FAM90A1 FBF1 FHIT FLAD1 FLJ38668 FXR2 GATA2 GEM GGA2 GMCL1P1 GPANK1 GPKOW HAUS1 HOXB5 HSPB7 IQCE IQUB JOSD1 KAT5 KIFC3 KLHL42 KRT6A LGALS8 LINC00526 LINC01018 LMO2 LNX1 LOC729603 MDM2 MKRN3 MLH1 MORN4 MRPL4 MRPL45 MTFR2 NEK6 NFU1 NXT2 PHF1 PIAS2 PIK3R2 PITX1 PKP4 POLI POLL POM121 PPIL2 PPP1R18 PSMA1 RAD18 RIBC2 RNF126 RNF213 RNF32 RNF34 RSRC2 RTP5 SF1 SH2D4A SIAH1 SLC25A6 SMG9 SNAI1 SNAI2 SNRPB SORBS3 SPG21 STK19 SUMO1P1 TBC1D22B TMSB4X TNFAIP3 TRAF1 TRAIP TRIM27 TRIM29 TRIM31 TRIM32 TRIM42 TROAP TSG101 TSHZ3 TXNDC5 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2H UBE2I UBE2U UBOX5 USP2 USP20 USP21 UTP23 WDR25 ZC2HC1C ZNF250 ZNF564 ZNF581
Entrez ID		55738	373
HPRD ID		06443	03449
Ensembl ID		ENSG00000101199	ENSG00000113595
Uniprot IDs		B7Z3U0 B7Z8H8 E7EV62 Q53F62 Q8N6T3	P36406
PDB IDs		3DWD 3O47
Enriched GO Terms of Interacting Partners?		Triglyceride Catabolic Process Acylglycerol Catabolic Process Vesicle-mediated Transport COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Response To Extracellular Stimulus Protein-lipid Complex Assembly Protein Transport Establishment Of Protein Localization Plasma Lipoprotein Particle Remodeling Cholesterol Efflux Cellular Component Assembly Triglyceride Metabolic Process Protein Localization Vesicle Targeting, To, From Or Within Golgi Neutral Lipid Metabolic Process Response To Nutrient Levels Cholesterol Metabolic Process Plasma Lipoprotein Particle Clearance Sterol Metabolic Process Localization Within Membrane Vesicle Targeting Autophagic Vacuole Assembly Transport Cellular Lipid Catabolic Process Autophagy Regulation Of Catalytic Activity Response To Light Stimulus Macroautophagy Triglyceride Mobilization Very-low-density Lipoprotein Particle Assembly Chylomicron Remnant Clearance Membrane Organization Regulation Of Plasma Lipoprotein Particle Levels Low-density Lipoprotein Particle Remodeling Cholesterol Transport Sterol Transport Glycerolipid Metabolic Process Negative Regulation Of Cholesterol Transport Regulation Of Signaling Phospholipid Efflux Negative Regulation Of Hydrolase Activity Endocytosis Regulation Of Protein Processing Regulation Of Proteolysis Phototransduction, Visible Light Cholesterol Homeostasis Cellular Response To Extracellular Stimulus Sterol Homeostasis	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Regulation Of Protein Catabolic Process Proteolysis Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Programmed Cell Death Regulation Of Metabolic Process Cellular Response To Stress Positive Regulation Of Metabolic Process Cell Death Death Gene Expression RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Biosynthetic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia Protein Metabolic Process Cellular Response To Decreased Oxygen Levels Regulation Of Transcription, DNA-templated Regulation Of Proteolysis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Oxygen Levels Regulation Of Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process
Tagcloud ?		accelerated adaptors adp associates cargo cathepsin cation cimpr clathrin copi ear endosomes exit explaining gga ggas golgi mannose perturbed rescued retrograde ribosylation slowed sorting traffic	344r abrogated adaptor antiviral conjugation defense e3 ectopic embryo helicase ikkgamma innate irf3 k165 k27 lys mda5 modulator multipoints nemo polyubiquitination rig substantially tightly tlr3 tlrs toll triparite ubiquitin
Tagcloud (Difference) ?		accelerated adaptors adp associates cargo cathepsin cation cimpr clathrin copi ear endosomes exit explaining gga ggas golgi mannose perturbed rescued retrograde ribosylation slowed sorting traffic	344r abrogated adaptor antiviral conjugation defense e3 ectopic embryo helicase ikkgamma innate irf3 k165 k27 lys mda5 modulator multipoints nemo polyubiquitination rig substantially tightly tlr3 tlrs toll triparite ubiquitin
Tagcloud (Intersection) ?