ARFGAP1 and RABGAP1L

Number of citations of the paper that reports this interaction (PubMedID 25814554)
62

Data Source:
BioGRID (two hybrid)

		ARFGAP1	RABGAP1L
Description		ARF GTPase activating protein 1	RAB GTPase activating protein 1 like
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Synapse	Nucleus Cytoplasm Endosome Early Endosome Golgi Apparatus Cytoplasmic Vesicle
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Protein Transport Vesicle-mediated Transport Regulation Of Endocytosis Regulation Of ARF Protein Signal Transduction	Endocytosis Protein Transport Regulation Of Protein Localization
Pathways		XBP1(S) activates chaperone genes COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Adult body size ( 32376654) Caffeine consumption from coffee or tea ( 33287642) Caffeine consumption from tea ( 33287642) Cerebrospinal fluid t-tau:AB1-42 ratio ( 26252872) Chronotype ( 30696823) Daytime nap ( 33568662) Femur bone mineral density x serum urate levels interaction ( 34046847) Medication use (anilides) ( 31015401) Neutrophil count ( 32888494) Systemic lupus erythematosus ( 26606652 33536424) Tea consumption ( 31046077) White blood cell count ( 32888494)
Interacting Genes		39 interacting genes: AGTR1 APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CRYAA CSNK1D CYTH2 FOS GABARAPL1 GABARAPL2 GRN HRAS KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RABGAP1L RASIP1 REEP5 RFC3 RGS2 RPL11 SLC25A21-AS1 SLC6A1 SMN1 SNCA TK1 TMED2 TRIM23	12 interacting genes: ACAP1 ARFGAP1 DBN1 GABARAPL1 MAP1LC3A RAB13 RAB34 RAB36 RB1 TSPAN2 UQCC2 WDFY3
Entrez ID		55738	9910
HPRD ID		06443	16464
Ensembl ID		ENSG00000101199	ENSG00000152061
Uniprot IDs		Q53F62 Q8N6T3	A0A0U1RRM5 A0A804HKD7 B7ZAP0 F1LJ00 F5H8L0 Q5R372 Q9UEL5 Q9Y3L8
PDB IDs		3DWD 3O47	3HZJ
Enriched GO Terms of Interacting Partners?		Intermediate-density Lipoprotein Particle Protein-containing Complex Organization Phospholipid Binding Vesicle-mediated Transport Very-low-density Lipoprotein Particle Golgi Apparatus Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Protein-containing Complex Assembly Lipoprotein Metabolic Process Plasma Lipoprotein Particle Remodeling Cellular Response To Nitrogen Starvation Protein-containing Complex Remodeling Cellular Component Assembly Regulation Of Proteolysis Cytoplasmic Vesicle Beta-tubulin Binding Vacuole Organization Chylomicron Phosphatidylethanolamine Binding Low-density Lipoprotein Particle Chylomicron Remnant Negative Regulation Of Transport Locomotory Exploration Behavior Lipoprotein Particle Low-density Lipoprotein Particle Remodeling COPI-coated Vesicle Membrane Endocytosis Regulation Of Small Molecule Metabolic Process Regulation Of Neuronal Synaptic Plasticity Import Into Cell Cytosol Golgi Membrane Growth Cone Establishment Of Protein Localization Regulation Of Protein Catabolic Process Protein Transport Establishment Of Localization In Cell Cellular Response To Nutrient Levels Low-density Lipoprotein Particle Receptor Binding Regulation Of Long-term Neuronal Synaptic Plasticity Astrocyte Activation Involved In Immune Response Plasma Lipoprotein Particle Clearance Autophagosome Neutral Lipid Metabolic Process Cholesterol Efflux Microglial Cell Activation Positive Regulation Of Inflammatory Response Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance	Autophagosome Autophagosome Membrane Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Macroautophagy Intracellular Protein Localization Protein Transport Trans-Golgi Network To Recycling Endosome Transport Mitophagy Autophagosome Maturation Golgi To Plasma Membrane Transport Positive Regulation Of Receptor Localization To Synapse Cell Communication By Chemical Coupling Membrane GTPase Activity Cellular Response To Insulin Stimulus Establishment Of Protein Localization GTP Binding Post-Golgi Vesicle-mediated Transport Plasma Membrane Bounded Cell Projection Organization Cytoplasmic Vesicle Recycling Endosome Membrane Protein Localization To Cell Leading Edge Golgi Apparatus Establishment Of Sertoli Cell Barrier Regulation Of Smoothened Signaling Pathway Ubiquitin Protein Ligase Binding Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Lipid Kinase Activity PML Body Chromatin Lock Complex Positive Regulation Of Collagen Fibril Organization Microglia Development Autophagy Autophagosome Organization Autophagy Of Mitochondrion Autophagosome Assembly Cellular Response To Oxygen-glucose Deprivation Phospholipid Binding
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