Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
ARFGAP1 and MED27
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
ARFGAP1
MED27
Gene Name
ADP-ribosylation factor GTPase activating protein 1
mediator complex subunit 27
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Golgi-associated Vesicle Membrane
Synapse
Nucleus
Nucleoplasm
Transcription Factor Complex
Nucleolus
Cytoplasm
Mediator Complex
Molecular Function
GTPase Activator Activity
Protein Binding
ARF GTPase Activator Activity
Zinc Ion Binding
Transcription Coactivator Activity
Protein Binding
Biological Process
Retrograde Vesicle-mediated Transport, Golgi To ER
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Protein Transport
Endoplasmic Reticulum Unfolded Protein Response
Regulation Of ARF GTPase Activity
Positive Regulation Of GTPase Activity
Cellular Protein Metabolic Process
COPI Coating Of Golgi Vesicle
Membrane Organization
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Stem Cell Maintenance
Pathways
IRE1alpha activates chaperones
COPI Mediated Transport
XBP1(S) activates chaperone genes
Golgi to ER Retrograde Transport
Unfolded Protein Response (UPR)
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions
31 interactors:
APOB
APOC3
APOE
APP
ARF1
ASB10
COPA
COPS5
CSNK1D
CYTH2
FOS
GABARAPL2
GRN
KDELR1
KRTAP10-9
KRTAP3-2
KRTAP9-2
LRRK2
MAP1LC3B
MED27
PRKACB
RAB23
RASIP1
REEP5
RFC3
RGS2
RPL11
SMN1
TK1
TMED2
TRIM23
9 interactors:
AFP
ARFGAP1
MED19
MED22
MED30
MED8
MED9
RBPJ
SOX5
Entrez ID
55738
9442
HPRD ID
06443
05438
Ensembl ID
ENSG00000101199
ENSG00000160563
Uniprot IDs
B7Z3U0
B7Z8H8
E7EV62
Q53F62
Q8N6T3
Q6P2C8
PDB IDs
3DWD
3O47
Enriched GO Terms of Interacting Partners
?
Triglyceride Catabolic Process
Acylglycerol Catabolic Process
Vesicle-mediated Transport
COPI-coated Vesicle Budding
COPI Coating Of Golgi Vesicle
Golgi Vesicle Budding
Response To Extracellular Stimulus
Protein-lipid Complex Assembly
Protein Transport
Establishment Of Protein Localization
Plasma Lipoprotein Particle Remodeling
Cholesterol Efflux
Cellular Component Assembly
Triglyceride Metabolic Process
Protein Localization
Vesicle Targeting, To, From Or Within Golgi
Neutral Lipid Metabolic Process
Response To Nutrient Levels
Cholesterol Metabolic Process
Plasma Lipoprotein Particle Clearance
Sterol Metabolic Process
Localization Within Membrane
Vesicle Targeting
Autophagic Vacuole Assembly
Transport
Cellular Lipid Catabolic Process
Autophagy
Regulation Of Catalytic Activity
Response To Light Stimulus
Macroautophagy
Triglyceride Mobilization
Very-low-density Lipoprotein Particle Assembly
Chylomicron Remnant Clearance
Membrane Organization
Regulation Of Plasma Lipoprotein Particle Levels
Low-density Lipoprotein Particle Remodeling
Cholesterol Transport
Sterol Transport
Glycerolipid Metabolic Process
Negative Regulation Of Cholesterol Transport
Regulation Of Signaling
Phospholipid Efflux
Negative Regulation Of Hydrolase Activity
Endocytosis
Regulation Of Protein Processing
Regulation Of Proteolysis
Phototransduction, Visible Light
Cholesterol Homeostasis
Cellular Response To Extracellular Stimulus
Sterol Homeostasis
Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Timing Of Cell Differentiation
Regulation Of Development, Heterochronic
RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
DNA-templated Transcription, Initiation
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Epidermal Cell Fate Specification
Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment
Positive Regulation Of Ephrin Receptor Signaling Pathway
Arterial Endothelial Cell Fate Commitment
Cellular Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Regulation Of Metabolic Process
Blood Vessel Lumenization
Blood Vessel Endothelial Cell Fate Specification
Nitrogen Compound Metabolic Process
Protein Secretion
Endothelial Cell Fate Specification
Stem Cell Maintenance
Clara Cell Differentiation
Positive Regulation Of Mesenchymal Stem Cell Differentiation
Interleukin-4 Secretion
Positive Regulation Of Transcription Of Notch Receptor Target
Regulation Of Cellular Process
Hair Follicle Maturation
Regulation Of Timing Of Neuron Differentiation
Auditory Receptor Cell Fate Commitment
Dorsal Aorta Morphogenesis
Arterial Endothelial Cell Differentiation
Regulation Of Mesenchymal Stem Cell Differentiation
Dorsal Aorta Development
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation
Endocardium Morphogenesis
Endothelial Tube Morphogenesis
Tagcloud
?
accelerated
adaptors
adp
associates
cargo
cathepsin
cation
cimpr
clathrin
copi
ear
endosomes
exit
explaining
gga
ggas
golgi
mannose
perturbed
rescued
retrograde
ribosylation
slowed
sorting
traffic
Tagcloud (Difference)
?
accelerated
adaptors
adp
associates
cargo
cathepsin
cation
cimpr
clathrin
copi
ear
endosomes
exit
explaining
gga
ggas
golgi
mannose
perturbed
rescued
retrograde
ribosylation
slowed
sorting
traffic
Tagcloud (Intersection)
?