ARFGAP1 and ASB10

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ARFGAP1	ASB10
Gene Name		ADP-ribosylation factor GTPase activating protein 1	ankyrin repeat and SOCS box containing 10
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Golgi-associated Vesicle Membrane Synapse	Nucleus Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding ARF GTPase Activator Activity Zinc Ion Binding
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To ER Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Protein Transport Endoplasmic Reticulum Unfolded Protein Response Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity Cellular Protein Metabolic Process COPI Coating Of Golgi Vesicle Membrane Organization	Protein Ubiquitination Intracellular Signal Transduction
Pathways		IRE1alpha activates chaperones COPI Mediated Transport XBP1(S) activates chaperone genes Golgi to ER Retrograde Transport Unfolded Protein Response (UPR)	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		31 interactors: APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GRN KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RASIP1 REEP5 RFC3 RGS2 RPL11 SMN1 TK1 TMED2 TRIM23	4 interactors: AGR3 ARFGAP1 KDM1A MRPL23
Entrez ID		55738	136371
HPRD ID		06443	10666
Ensembl ID		ENSG00000101199	ENSG00000146926
Uniprot IDs		B7Z3U0 B7Z8H8 E7EV62 Q53F62 Q8N6T3	Q8WXI3
PDB IDs		3DWD 3O47
Enriched GO Terms of Interacting Partners?		Triglyceride Catabolic Process Acylglycerol Catabolic Process Vesicle-mediated Transport COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Response To Extracellular Stimulus Protein-lipid Complex Assembly Protein Transport Establishment Of Protein Localization Plasma Lipoprotein Particle Remodeling Cholesterol Efflux Cellular Component Assembly Triglyceride Metabolic Process Protein Localization Vesicle Targeting, To, From Or Within Golgi Neutral Lipid Metabolic Process Response To Nutrient Levels Cholesterol Metabolic Process Plasma Lipoprotein Particle Clearance Sterol Metabolic Process Localization Within Membrane Vesicle Targeting Autophagic Vacuole Assembly Transport Cellular Lipid Catabolic Process Autophagy Regulation Of Catalytic Activity Response To Light Stimulus Macroautophagy Triglyceride Mobilization Very-low-density Lipoprotein Particle Assembly Chylomicron Remnant Clearance Membrane Organization Regulation Of Plasma Lipoprotein Particle Levels Low-density Lipoprotein Particle Remodeling Cholesterol Transport Sterol Transport Glycerolipid Metabolic Process Negative Regulation Of Cholesterol Transport Regulation Of Signaling Phospholipid Efflux Negative Regulation Of Hydrolase Activity Endocytosis Regulation Of Protein Processing Regulation Of Proteolysis Phototransduction, Visible Light Cholesterol Homeostasis Cellular Response To Extracellular Stimulus Sterol Homeostasis	Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Positive Regulation Of Megakaryocyte Differentiation COPI Coating Of Golgi Vesicle Positive Regulation Of Hormone Biosynthetic Process COPI-coated Vesicle Budding Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Golgi Vesicle Budding Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Histone H3-K4 Methylation Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hormone Biosynthetic Process Vesicle Targeting, To, From Or Within Golgi Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Lysine Demethylation Regulation Of Hormone Metabolic Process Histone Demethylation Regulation Of Erythrocyte Differentiation Retrograde Vesicle-mediated Transport, Golgi To ER Protein Demethylation Localization Within Membrane Vesicle Targeting Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of DNA Binding Organelle Organization Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Regulation Of Histone Methylation Positive Regulation Of Nuclease Activity Positive Regulation Of Neural Precursor Cell Proliferation Pituitary Gland Development Negative Regulation Of Protein Binding
Tagcloud ?		accelerated adaptors adp associates cargo cathepsin cation cimpr clathrin copi ear endosomes exit explaining gga ggas golgi mannose perturbed rescued retrograde ribosylation slowed sorting traffic
Tagcloud (Difference) ?		accelerated adaptors adp associates cargo cathepsin cation cimpr clathrin copi ear endosomes exit explaining gga ggas golgi mannose perturbed rescued retrograde ribosylation slowed sorting traffic
Tagcloud (Intersection) ?