DZIP1 and DAZ4

Number of citations of the paper that reports this interaction (PubMedID 12511597)
35

Data Source:
HPRD (two hybrid)

		DZIP1	DAZ4
Description		DAZ interacting zinc finger protein 1	deleted in azoospermia 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Nuclear Speck Centriolar Satellite Ciliary Basal Body Cell Projection Ciliary Transition Fiber Ciliary Base	Nucleus Cytoplasm Protein-containing Complex
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding Molecular Adaptor Activity BBSome Binding	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Activator Activity
	Biological Process	Smoothened Signaling Pathway Germ Cell Development Spermatogenesis Heart Development Cell Projection Organization Cell Differentiation Ciliary Basal Body Organization Protein Localization To Organelle Cilium Organization Establishment Of Protein Localization Positive Regulation Of Cilium Assembly Establishment Of Localization In Cell Cilium Assembly Protein Localization To Cilium Sperm Flagellum Assembly Protein-containing Complex Localization To Centriolar Satellite Positive Regulation Of Protein Localization To Cilium	Spermatogenesis Cell Differentiation Positive Regulation Of Translational Initiation 3'-UTR-mediated MRNA Stabilization
Pathways		Hedgehog 'on' state
Drugs
Diseases
GWAS		Glomerular filtration rate (cystatin C) ( 26831199) Response to statins (LDL cholesterol change) ( 25350695)
Interacting Genes		12 interacting genes: DAZ1 DAZ4 LUC7L2 MECOM MOS OPTN PPP1R18 PPP2R5A PRPF40A RNF10 TIAM1 TNS2	6 interacting genes: BOLL CFTR DAZL DZIP1 PUM2 QKI
Entrez ID		22873	57135
HPRD ID		16363	13117
Ensembl ID		ENSG00000134874	ENSG00000205916
Uniprot IDs		B3KSP1 Q86YF9	A0A804HKV4 Q86SG3
PDB IDs
Enriched GO Terms of Interacting Partners?		Translation Activator Activity 3'-UTR-mediated MRNA Stabilization Kinase Binding U2-type Prespliceosome U1 SnRNP	MRNA 3'-UTR Binding Regulation Of MRNA Stability Regulation Of RNA Stability MRNA Stabilization Developmental Process Involved In Reproduction Negative Regulation Of MRNA Catabolic Process Regulation Of MRNA Metabolic Process RNA Stabilization Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Metabolic Process Regulation Of Translation Translation Activator Activity Reproductive Process 3'-UTR-mediated MRNA Stabilization Post-transcriptional Regulation Of Gene Expression Germ Cell Development Stress Granule Assembly MiRNA Binding Positive Regulation Of Translational Initiation Negative Regulation Of Catabolic Process Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Internal N(7)-methylguanine-containing RNA Reader Activity Pumilio-response Element Binding Regulation Of Biological Quality Male Gamete Generation Spermatogenesis Cytoplasmic Stress Granule Positive Regulation Of Anion Channel Activity Cellular Developmental Process Developmental Process Regulation Of Translational Initiation Female Meiosis II Gamete Generation Nucleic Acid Binding Myofibroblast Contraction Positive Regulation Of MRNA Catabolic Process Negative Regulation Of MiRNA Catabolic Process BBSome Binding Protein-containing Complex Localization To Centriolar Satellite Positive Regulation Of Sprouting Of Injured Axon RNA Binding Regulation Of Protein Metabolic Process Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of MRNA Metabolic Process Cell Maturation Positive Regulation Of Translation Organelle Assembly Positive Regulation Of Enamel Mineralization
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