DZIP1 and PPP1R18

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DZIP1	PPP1R18
Description		DAZ interacting zinc finger protein 1	protein phosphatase 1 regulatory subunit 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Nuclear Speck Centriolar Satellite Ciliary Basal Body Cell Projection Ciliary Transition Fiber Ciliary Base	Cytoplasm Cytoskeleton
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding Molecular Adaptor Activity BBSome Binding	Actin Binding Protein Binding Phosphatase Binding
	Biological Process	Smoothened Signaling Pathway Germ Cell Development Spermatogenesis Heart Development Cell Projection Organization Cell Differentiation Ciliary Basal Body Organization Protein Localization To Organelle Cilium Organization Establishment Of Protein Localization Positive Regulation Of Cilium Assembly Establishment Of Localization In Cell Cilium Assembly Protein Localization To Cilium Sperm Flagellum Assembly Protein-containing Complex Localization To Centriolar Satellite Positive Regulation Of Protein Localization To Cilium
Pathways		Hedgehog 'on' state
Drugs
Diseases
GWAS		Glomerular filtration rate (cystatin C) ( 26831199) Response to statins (LDL cholesterol change) ( 25350695)	Autism spectrum disorder or schizophrenia ( 28540026) Chronic obstructive pulmonary disease ( 33909500) Hemoglobin levels ( 32327693) Lung cancer ( 28604730)
Interacting Genes		12 interacting genes: DAZ1 DAZ4 LUC7L2 MECOM MOS OPTN PPP1R18 PPP2R5A PRPF40A RNF10 TIAM1 TNS2	80 interacting genes: ABRA ACTN3 BICD2 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCDC88B CDR2L CEP70 COG6 DES DZIP1 EIF3L FAM9B FHL5 FSD2 GCC1 GFAP GMCL1 GOLGA2 GOLGA6L9 GOPC GRIPAP1 GTPBP3 HAP1 HOMER3 HOOK2 HSF2BP IKZF3 KASH5 KCTD9 KRT13 KRT15 KRT16 KRT19 KRT27 KRT31 KRT33B KRT34 KRT36 KRT40 LDOC1 LZTS1 LZTS2 MAD1L1 MAPK1 MEOX2 MID2 MRPL38 MTUS2 NACA NEFL PDE4DIP PIBF1 PLEKHF2 PPP1CA PPP1CC PPP1R13B PRPH SORBS3 SPDL1 STX11 TCF4 TEX11 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TRIM62 TRIM69 TSC1 TSGA10 VIM VPS52 ZMYND12 ZRANB1
Entrez ID		22873	170954
HPRD ID		16363	11172
Ensembl ID		ENSG00000134874	ENSG00000146112
Uniprot IDs		B3KSP1 Q86YF9	A0A024RCJ8 A0A0G2JHC2 Q6NYC8
PDB IDs
Enriched GO Terms of Interacting Partners?		Translation Activator Activity 3'-UTR-mediated MRNA Stabilization Kinase Binding U2-type Prespliceosome U1 SnRNP	Cytoskeleton Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytoskeleton Organization Intermediate Filament Organelle Organization Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Keratin Filament Structural Constituent Of Cytoskeleton Structural Molecule Activity Protein Binding Identical Protein Binding Intermediate Filament Cytoskeleton Microtubule-based Process Centrosome Morphogenesis Of An Epithelium Microtubule Cytoskeleton Organization Tissue Morphogenesis Cytosol Cytoplasm Microtubule Organizing Center Bergmann Glial Cell Differentiation Epithelial Cell Differentiation Microtubule Organizing Center Organization Negative Regulation Of Viral Transcription Intracellular Transport Developmental Process Regulation Of Viral Transcription Response To Muramyl Dipeptide Cellular Developmental Process Positive Regulation Of Skeletal Muscle Tissue Growth Establishment Of Localization In Cell Developmental Process Involved In Reproduction Establishment Of Protein Localization Dynein Light Intermediate Chain Binding Cytoskeleton-dependent Intracellular Transport Kinetochore Binding Regulation Of Autophagy Cell Differentiation Regulation Of Skeletal Muscle Tissue Growth Z Disc Intracellular Protein Localization Protein Transport Astrocyte Differentiation PTW/PP1 Phosphatase Complex Cellular Localization Organelle Transport Along Microtubule Cellular Response To Muramyl Dipeptide
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