SPRED1 and FAM118B

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		SPRED1	FAM118B
Gene Name		sprouty-related, EVH1 domain containing 1	family with sequence similarity 118, member B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Caveola	Cajal Body
	Molecular Function	Stem Cell Factor Receptor Binding Protein Binding Protein Kinase Binding Phosphatase Binding Protein Serine/threonine Kinase Inhibitor Activity
	Biological Process	Inactivation Of MAPK Activity Multicellular Organismal Development Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Phosphatase Activity Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Protein Deacetylation
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 23128233) Hypersomnia (HLA-DQB1*06:02 negative) ( 23646285)
Protein-Protein Interactions		11 interactors: CDKN1A DNAJB11 FAM118B KIT NAGK OSGEP PPP1CA RCC1 SUV39H1 TSC22D1 TTC19	26 interactors: BAG5 CEP70 CTSB FAM118A FAM20C GNB2 ING5 ITFG1 KIAA1377 MCM3AP MED31 NGEF QARS RASGRP2 RBM48 SDCBP SEMA5B SETDB1 SHC1 SPRED1 SUMO1 SUMO1P1 TMSB4X VIM ZNF235 ZNF746
Entrez ID		161742	79607
HPRD ID		11601	07952
Ensembl ID		ENSG00000166068	ENSG00000197798
Uniprot IDs		Q7Z699	J3KP39 Q9BPY3
PDB IDs		3SYX
Enriched GO Terms of Interacting Partners?		Cell Division Cell Cycle Rhythmic Process Response To Light Stimulus Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Mast Cell Proliferation Response To Radiation Response To Abiotic Stimulus Regulation Of Circadian Rhythm Positive Regulation Of Protein Kinase Activity Threonylcarbamoyladenosine Biosynthetic Process Kit Signaling Pathway Erythropoietin-mediated Signaling Pathway N-acetylmannosamine Metabolic Process Positive Regulation Of Kinase Activity Mast Cell Differentiation Positive Regulation Of Transferase Activity Phosphatidylinositol-mediated Signaling Digestive Tract Development Cellular Response To Growth Factor Stimulus Positive Regulation Of Programmed Cell Death Mast Cell Chemotaxis Cellular Response To Erythropoietin N-acetylneuraminate Catabolic Process Response To Growth Factor Digestive System Development Positive Regulation Of Cell Death RNA Modification G1/S Transition Of Mitotic Cell Cycle Threonylcarbamoyladenosine Metabolic Process Intestinal Epithelial Cell Maturation Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Catalytic Activity Tube Development Regulation Of Cell Death Cellular Response To Fibroblast Growth Factor Stimulus Melanocyte Migration Histone H3-K9 Dimethylation Positive Regulation Of Protein Phosphorylation Response To Fibroblast Growth Factor Regulation Of Protein Kinase Activity Cellular Response To UV-B Positive Regulation Of Long-term Neuronal Synaptic Plasticity Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Ran GTPase Activity Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein See more	Regulation Of Metabolic Process Developmental Process Anatomical Structure Development Regulation Of Signal Transduction Platelet Activation Regulation Of Signaling Glutaminyl-tRNA Aminoacylation Osteoclast Maturation Ras Protein Signal Transduction Organelle Organization Regulation Of Cellular Component Organization Multicellular Organismal Development Peptidyl-lysine Modification Prolyl-tRNA Aminoacylation Regulation Of Cellular Process Small GTPase Mediated Signal Transduction Actin Filament-based Process Negative Regulation Of Dendritic Spine Morphogenesis Cytoskeleton Organization Ephrin Receptor Signaling Pathway Positive Regulation Of Extracellular Vesicular Exosome Assembly Glutamyl-tRNA Aminoacylation PML Body Organization Negative Regulation Of Protein Refolding Odontoblast Differentiation Regulation Of Intracellular Signal Transduction See more
Tagcloud ?		3g bim bolsters btg3 cdc25a cfue cyclinb1 deployed eaf1 engages epo epor erythroblast erythroblasts gas5 interrogate lyl1 maturing pim1 pim3 presently proerythroblast serpina sf13c socs2 sophisticated tnfr trib3
Tagcloud (Difference) ?		3g bim bolsters btg3 cdc25a cfue cyclinb1 deployed eaf1 engages epo epor erythroblast erythroblasts gas5 interrogate lyl1 maturing pim1 pim3 presently proerythroblast serpina sf13c socs2 sophisticated tnfr trib3
Tagcloud (Intersection) ?