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SPRED1 and FAM118B
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
SPRED1
FAM118B
Gene Name
sprouty-related, EVH1 domain containing 1
family with sequence similarity 118, member B
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Caveola
Cajal Body
Molecular Function
Stem Cell Factor Receptor Binding
Protein Binding
Protein Kinase Binding
Phosphatase Binding
Protein Serine/threonine Kinase Inhibitor Activity
Biological Process
Inactivation Of MAPK Activity
Multicellular Organismal Development
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Phosphatase Activity
Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Protein Deacetylation
Pathways
Drugs
Diseases
GWAS
Crohn's disease (
23128233
)
Hypersomnia (HLA-DQB1*06:02 negative) (
23646285
)
Protein-Protein Interactions
11 interactors:
CDKN1A
DNAJB11
FAM118B
KIT
NAGK
OSGEP
PPP1CA
RCC1
SUV39H1
TSC22D1
TTC19
26 interactors:
BAG5
CEP70
CTSB
FAM118A
FAM20C
GNB2
ING5
ITFG1
KIAA1377
MCM3AP
MED31
NGEF
QARS
RASGRP2
RBM48
SDCBP
SEMA5B
SETDB1
SHC1
SPRED1
SUMO1
SUMO1P1
TMSB4X
VIM
ZNF235
ZNF746
Entrez ID
161742
79607
HPRD ID
11601
07952
Ensembl ID
ENSG00000166068
ENSG00000197798
Uniprot IDs
Q7Z699
J3KP39
Q9BPY3
PDB IDs
3SYX
Enriched GO Terms of Interacting Partners
?
Cell Division
Cell Cycle
Rhythmic Process
Response To Light Stimulus
Mast Cell Cytokine Production
Melanocyte Adhesion
Dendritic Cell Cytokine Production
Mast Cell Proliferation
Response To Radiation
Response To Abiotic Stimulus
Regulation Of Circadian Rhythm
Positive Regulation Of Protein Kinase Activity
Threonylcarbamoyladenosine Biosynthetic Process
Kit Signaling Pathway
Erythropoietin-mediated Signaling Pathway
N-acetylmannosamine Metabolic Process
Positive Regulation Of Kinase Activity
Mast Cell Differentiation
Positive Regulation Of Transferase Activity
Phosphatidylinositol-mediated Signaling
Digestive Tract Development
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Programmed Cell Death
Mast Cell Chemotaxis
Cellular Response To Erythropoietin
N-acetylneuraminate Catabolic Process
Response To Growth Factor
Digestive System Development
Positive Regulation Of Cell Death
RNA Modification
G1/S Transition Of Mitotic Cell Cycle
Threonylcarbamoyladenosine Metabolic Process
Intestinal Epithelial Cell Maturation
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Positive Regulation Of Catalytic Activity
Tube Development
Regulation Of Cell Death
Cellular Response To Fibroblast Growth Factor Stimulus
Melanocyte Migration
Histone H3-K9 Dimethylation
Positive Regulation Of Protein Phosphorylation
Response To Fibroblast Growth Factor
Regulation Of Protein Kinase Activity
Cellular Response To UV-B
Positive Regulation Of Long-term Neuronal Synaptic Plasticity
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Ran GTPase Activity
Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein
Regulation Of Metabolic Process
Developmental Process
Anatomical Structure Development
Regulation Of Signal Transduction
Platelet Activation
Regulation Of Signaling
Glutaminyl-tRNA Aminoacylation
Osteoclast Maturation
Ras Protein Signal Transduction
Organelle Organization
Regulation Of Cellular Component Organization
Multicellular Organismal Development
Peptidyl-lysine Modification
Prolyl-tRNA Aminoacylation
Regulation Of Cellular Process
Small GTPase Mediated Signal Transduction
Actin Filament-based Process
Negative Regulation Of Dendritic Spine Morphogenesis
Cytoskeleton Organization
Ephrin Receptor Signaling Pathway
Positive Regulation Of Extracellular Vesicular Exosome Assembly
Glutamyl-tRNA Aminoacylation
PML Body Organization
Negative Regulation Of Protein Refolding
Odontoblast Differentiation
Regulation Of Intracellular Signal Transduction
Tagcloud
?
3g
bim
bolsters
btg3
cdc25a
cfue
cyclinb1
deployed
eaf1
engages
epo
epor
erythroblast
erythroblasts
gas5
interrogate
lyl1
maturing
pim1
pim3
presently
proerythroblast
serpina
sf13c
socs2
sophisticated
tnfr
trib3
Tagcloud (Difference)
?
3g
bim
bolsters
btg3
cdc25a
cfue
cyclinb1
deployed
eaf1
engages
epo
epor
erythroblast
erythroblasts
gas5
interrogate
lyl1
maturing
pim1
pim3
presently
proerythroblast
serpina
sf13c
socs2
sophisticated
tnfr
trib3
Tagcloud (Intersection)
?