SPRED1 and TTC19

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		SPRED1	TTC19
Gene Name		sprouty-related, EVH1 domain containing 1	tetratricopeptide repeat domain 19
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Caveola	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody
	Molecular Function	Stem Cell Factor Receptor Binding Protein Binding Protein Kinase Binding Phosphatase Binding Protein Serine/threonine Kinase Inhibitor Activity	Protein Binding
	Biological Process	Inactivation Of MAPK Activity Multicellular Organismal Development Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Phosphatase Activity Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Protein Deacetylation	Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 23128233) Hypersomnia (HLA-DQB1*06:02 negative) ( 23646285)
Protein-Protein Interactions		11 interactors: CDKN1A DNAJB11 FAM118B KIT NAGK OSGEP PPP1CA RCC1 SUV39H1 TSC22D1 TTC19	12 interactors: ATXN1 CCDC33 CCDC36 CHMP4A EIF4ENIF1 HPS6 L3MBTL3 NAB2 REL SPRED1 UBA1 UPF3B
Entrez ID		161742	54902
HPRD ID		11601	07899
Ensembl ID		ENSG00000166068	ENSG00000011295
Uniprot IDs		Q7Z699	Q6DKK2
PDB IDs		3SYX
Enriched GO Terms of Interacting Partners?		Cell Division Cell Cycle Rhythmic Process Response To Light Stimulus Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Mast Cell Proliferation Response To Radiation Response To Abiotic Stimulus Regulation Of Circadian Rhythm Positive Regulation Of Protein Kinase Activity Threonylcarbamoyladenosine Biosynthetic Process Kit Signaling Pathway Erythropoietin-mediated Signaling Pathway N-acetylmannosamine Metabolic Process Positive Regulation Of Kinase Activity Mast Cell Differentiation Positive Regulation Of Transferase Activity Phosphatidylinositol-mediated Signaling Digestive Tract Development Cellular Response To Growth Factor Stimulus Positive Regulation Of Programmed Cell Death Mast Cell Chemotaxis Cellular Response To Erythropoietin N-acetylneuraminate Catabolic Process Response To Growth Factor Digestive System Development Positive Regulation Of Cell Death RNA Modification G1/S Transition Of Mitotic Cell Cycle Threonylcarbamoyladenosine Metabolic Process Intestinal Epithelial Cell Maturation Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Catalytic Activity Tube Development Regulation Of Cell Death Cellular Response To Fibroblast Growth Factor Stimulus Melanocyte Migration Histone H3-K9 Dimethylation Positive Regulation Of Protein Phosphorylation Response To Fibroblast Growth Factor Regulation Of Protein Kinase Activity Cellular Response To UV-B Positive Regulation Of Long-term Neuronal Synaptic Plasticity Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Ran GTPase Activity Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein
Tagcloud ?		3g bim bolsters btg3 cdc25a cfue cyclinb1 deployed eaf1 engages epo epor erythroblast erythroblasts gas5 interrogate lyl1 maturing pim1 pim3 presently proerythroblast serpina sf13c socs2 sophisticated tnfr trib3
Tagcloud (Difference) ?		3g bim bolsters btg3 cdc25a cfue cyclinb1 deployed eaf1 engages epo epor erythroblast erythroblasts gas5 interrogate lyl1 maturing pim1 pim3 presently proerythroblast serpina sf13c socs2 sophisticated tnfr trib3
Tagcloud (Intersection) ?