UFSP2 and CAPN1

Number of citations of the paper that reports this interaction (PMID 12358155)
3

Data Source:
HPRD (two hybrid)

		UFSP2	CAPN1
Gene Name		UFM1-specific peptidase 2	calpain 1, (mu/I) large subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum	Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Thiolester Hydrolase Activity UFM1 Hydrolase Activity	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding
	Biological Process	Proteolysis Regulation Of Intracellular Estrogen Receptor Signaling Pathway	Proteolysis Positive Regulation Of Cell Proliferation Extracellular Matrix Disassembly Extracellular Matrix Organization Receptor Catabolic Process
Pathways			Degradation of the extracellular matrix
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CAPN1 LIG4	50 interactors: ACTC1 ACTN2 AES ARF6 BCL2L1 BID CAPNS1 CASP14 CAST CBL CDK5R1 CLEC4G COL1A1 COL3A1 CREG1 CTSC DES ECHS1 F2R F2RL1 FANCA FANCG FHL2 GNG12 GPT GRIN2B HNRNPD IL1A INPP4A ITGB3 KNG1 LAMTOR1 MYBPC3 NDUFB7 NFE2L1 NFKBIA PRMT5 PSEN2 PTGDS RAD21 SH3BGR SLIT3 SPTAN1 SPTBN1 STAT3 SYNE1 TINAGL1 TP53 UFSP2 VIM
Entrez ID		55325	823
HPRD ID		07741	00253
Ensembl ID			ENSG00000014216
Uniprot IDs		B3KRI4 D6RGX2 Q9NUQ7	B2RDI5 B4DWH5 P07384
PDB IDs			1ZCM 2ARY
Enriched GO Terms of Interacting Partners?		DNA Ligation Involved In DNA Recombination Lagging Strand Elongation Pro-B Cell Differentiation Establishment Of Integrated Proviral Latency Establishment Of Viral Latency Immunoglobulin V(D)J Recombination DNA Ligation Involved In DNA Repair T Cell Receptor V(D)J Recombination Lymphoid Progenitor Cell Differentiation Receptor Catabolic Process DNA Ligation Positive Regulation Of Cell Proliferation Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Lithium Ion Single Strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Isotype Switching V(D)J Recombination DNA Strand Elongation Involved In DNA Replication Response To Lithium Ion DNA Strand Elongation Response To X-ray Somatic Recombination Of Immunoglobulin Gene Segments Somatic Diversification Of Immunoglobulins Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response Regulation Of Cell Proliferation B Cell Activation Involved In Immune Response Response To Gamma Radiation Neuron Apoptotic Process Immunoglobulin Production Positive Regulation Of Fibroblast Proliferation Neuron Death T Cell Differentiation In Thymus Somatic Stem Cell Maintenance Receptor Metabolic Process Nucleotide-excision Repair Extracellular Matrix Disassembly Regulation Of Fibroblast Proliferation DNA-dependent DNA Replication DNA Biosynthetic Process Cellular Response To Metal Ion Cellular Response To Inorganic Substance Response To Ionizing Radiation Double-strand Break Repair Hematopoietic Progenitor Cell Differentiation Stem Cell Maintenance T Cell Differentiation Leukocyte Activation Involved In Immune Response B Cell Activation Negative Regulation Of Neuron Apoptotic Process	Apoptotic Process Regulation Of Signal Transduction Programmed Cell Death Cell Death Death Movement Of Cell Or Subcellular Component Response To Stimulus Regulation Of Cell Death Regulation Of Signaling Muscle Filament Sliding Actin-myosin Filament Sliding Developmental Process Regulation Of Apoptotic Process Positive Regulation Of Signal Transduction Anatomical Structure Development Organ Development Response To Organic Substance Actin-mediated Cell Contraction Cell Differentiation Cell Development Protein Localization To Nucleus Protein Localization To Organelle System Development Enzyme Linked Receptor Protein Signaling Pathway Actin Filament-based Movement Multicellular Organismal Development Cell Surface Receptor Signaling Pathway Muscle Contraction Response To External Stimulus Anatomical Structure Morphogenesis Cellular Response To Stimulus Cell Activation Regulation Of Cellular Process Muscle System Process Axon Guidance Positive Regulation Of Transport Blood Coagulation Hemostasis Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Localization Rhythmic Process Platelet Activation Wound Healing Negative Regulation Of Cell Death Positive Regulation Of Cell Death Regulation Of Protein Localization Regulation Of Cellular Component Organization Protein Import Into Nucleus Response To Stress
Tagcloud ?			5k3 alpl armitage beadchip bovinesnp50 bull catsper1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36
Tagcloud (Difference) ?			5k3 alpl armitage beadchip bovinesnp50 bull catsper1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch klhl1 loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36
Tagcloud (Intersection) ?