RPGRIP1 and CSPP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		RPGRIP1	CSPP1
Description		RPGR interacting protein 1	centrosome and spindle pole associated protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Cilium Axoneme Microtubule Cytoskeleton Photoreceptor Connecting Cilium Cell Projection Neuron Projection Intercellular Bridge Non-motile Cilium Photoreceptor Distal Connecting Cilium	Spindle Pole Nucleoplasm Cytoplasm Centrosome Spindle Cytoskeleton Microtubule Cilium Centriolar Satellite Ciliary Basal Body Cell Projection
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Visual Perception Eye Photoreceptor Cell Development Retinal Rod Cell Development Retina Development In Camera-type Eye Neural Precursor Cell Proliferation Non-motile Cilium Assembly	Positive Regulation Of Cytokinesis Positive Regulation Of Cell Division
Pathways
Drugs
Diseases		Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)	Hip circumference adjusted for BMI ( 28552196)
Interacting Genes		26 interacting genes: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RNF6 RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564 ZNF688	8 interacting genes: CIP2A GOLGA2 MRFAP1L1 PFDN5 RINT1 RPGRIP1 TRIM14 UBR5
Entrez ID		57096	79848
HPRD ID		05673	07991
Ensembl ID		ENSG00000092200	ENSG00000104218
Uniprot IDs		Q96KN7	A0A6Q8PF96 A0A6Q8PGS3 A0A6Q8PHN8 A0A7I2PHE7 A0A7I2V3Z9 A0A7I2V4R5 A0A7I2V5J9 A0A7I2V5L8 A0A7I2V5N5 A0A7I2V5W3 A0A7I2YQH9 Q1MSJ5 Q9H688
PDB IDs		4QAM
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Nucleus Regulation Of RNA Biosynthetic Process Ciliary Basal Body	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport RNA Polymerase III Assembly RNA Polymerase I Assembly RNA Polymerase II Core Complex Assembly Retina Development In Camera-type Eye Cytoplasm Protein Quality Control By The Ubiquitin-proteasome System Heterochromatin Boundary Formation Photoreceptor Distal Connecting Cilium Broken Chromosome Clustering Dsl1/NZR Complex
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