RPGRIP1 and GATAD2B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RPGRIP1	GATAD2B
Gene Name		retinitis pigmentosa GTPase regulator interacting protein 1	GATA zinc finger domain containing 2B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Axoneme Photoreceptor Connecting Cilium	Nuclear Chromatin Nucleoplasm Nuclear Speck Protein Complex
	Molecular Function	Protein Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Zinc Ion Binding Nucleosomal DNA Binding
	Biological Process	Visual Perception Eye Photoreceptor Cell Development Response To Stimulus Retina Development In Camera-type Eye	Transcription, DNA-templated Regulation Of Transcription, DNA-templated ATP-dependent Chromatin Remodeling
Pathways			Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS			Lentiform nucleus volume ( 22903471)
Protein-Protein Interactions		24 interactors: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564	20 interactors: CALCOCO2 CEP70 GOLGA2 HDAC1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE KAT2B MBD2 MBD3 PRKAB2 RBBP4 RBBP7 RPGRIP1 SMAD2 TEX11 TRAF1 TRIM27 USHBP1
Entrez ID		57096	57459
HPRD ID		05673	15094
Ensembl ID		ENSG00000092200	ENSG00000143614
Uniprot IDs		Q96KN7	Q8WXI9
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Fatty Acid Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Apoptotic Signaling Pathway Negative Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Negative Regulation Of Lipid Biosynthetic Process Photoreceptor Cell Development Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Androgen Receptor Activity Negative Regulation Of Lipid Metabolic Process Regulation Of Fatty Acid Metabolic Process Regulation Of Cellular Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Neural Retina Development Negative Regulation Of Cilium Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Eye Development Signal Transduction By P53 Class Mediator Amacrine Cell Differentiation Cellular Response To Indole-3-methanol	Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic ATP-dependent Chromatin Remodeling Chromatin Remodeling Chromosome Organization Chromatin Organization Protein Complex Assembly Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Organelle Organization Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly Chromatin Modification Negative Regulation Of Gene Expression DNA Packaging Cellular Macromolecular Complex Assembly Cellular Component Assembly Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process CENP-A Containing Nucleosome Assembly Gene Silencing DNA Conformation Change Chromatin Silencing Histone Exchange DNA Replication-independent Nucleosome Assembly Negative Regulation Of Biosynthetic Process Cell Cycle Centromere Complex Assembly Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation On Cytosine Chromatin Silencing At RDNA Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Viral Transcription Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Histone Modification Mitotic Cell Cycle RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cep76 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 tgl throw ttl	520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived tead1 transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Difference) ?		ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cep76 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 tgl throw ttl	520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived tead1 transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Intersection) ?