ZCCHC10 and NUDT14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ZCCHC10	NUDT14
Description		zinc finger CCHC-type containing 10	nudix hydrolase 14
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding UDP-sugar Diphosphatase Activity Hydrolase Activity Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides Identical Protein Binding Metal Ion Binding ADP-ribose Diphosphatase Activity
	Biological Process		Nucleoside Phosphate Metabolic Process Protein N-linked Glycosylation Via Asparagine Ribose Phosphate Metabolic Process
Pathways			Synthesis of dolichyl-phosphate-glucose
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045)	Brain morphology (MOSTest) ( 32665545) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Neutrophil count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		55 interacting genes: ANKRD36B ARGLU1 BEND7 CAVIN1 CEP63 CEP70 COIL CTNNBL1 DAB1 DPPA2 DZIP3 EEF1A1 ELOA2 EPB41 FAM9B FRA10AC1 GKAP1 HMGXB4 IK KCTD6 KPNA3 LNX1 LUC7L2 MAB21L3 MEOX1 NUDT14 PCBP1 PIN1 PPIG PRPF3 PRPF38A PRPF40A PRR13 PSME3 PTPN3 RBM39 RPL22 SART1 SDCBP SDCBP2 SF3B2 SF3B4 SFMBT1 SIAH1 SLU7 SNIP1 SNRPD2 STAC3 STX11 TFCP2 THAP1 TP53 U2AF1 ZBTB14 ZBTB8A	11 interacting genes: ARAF LNX1 LNX2 NIF3L1 NTAQ1 RAF1 REL TEPSIN TERF1 TERF2IP ZCCHC10
Entrez ID		54819	256281
HPRD ID		15699	14847
Ensembl ID		ENSG00000155329	ENSG00000183828
Uniprot IDs		B3KVL5 B4DU89 D6R9G7 D6RHC2 G3XAM1 Q8TBK6	B3KXY7 O95848
PDB IDs			3Q91 8OTV
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions U2-type Precatalytic Spliceosome MRNA Metabolic Process MRNA Processing Spliceosomal Complex Nucleoplasm Nuclear Speck RNA Metabolic Process RNA Processing Protein-RNA Complex Assembly Nucleus Precatalytic Spliceosome Nucleic Acid Metabolic Process RNA Binding U2-type Prespliceosome Assembly Protein Binding Identical Protein Binding U2 SnRNP Nucleobase-containing Compound Metabolic Process Catalytic Step 2 Spliceosome Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Macromolecule Metabolic Process U1 SnRNP Cajal Body U12-type Spliceosomal Complex U2-type Spliceosomal Complex Protein-containing Complex Assembly Pre-mRNA 3'-splice Site Binding RS Domain Binding U4/U6 X U5 Tri-snRNP Complex Cytosol Protein-containing Complex Organization MDM2/MDM4 Family Protein Binding Regulation Of Mitotic Cell Cycle Small Nuclear Ribonucleoprotein Complex MRNA Cis Splicing, Via Spliceosome U2-type Prespliceosome	Nuclear Telomere Cap Complex Shelterin Complex G-rich Strand Telomeric DNA Binding Telomere Capping MAP Kinase Kinase Kinase Activity Positive Regulation Of Peptidyl-serine Phosphorylation Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Regulation Of Peptidyl-serine Phosphorylation Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Protein-N-terminal Glutamine Amidohydrolase Activity Coated Vesicle Membrane Death-inducing Signaling Complex Assembly Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of DNA Recombination At Telomere Protein-N-terminal Asparagine Amidohydrolase Activity PDZ Domain Binding DNA Biosynthetic Process Regulation Of Protein Phosphorylation Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Phosphorylation Regulation Of Telomere Maintenance NF-kappaB Complex Telomere Organization Adenylate Cyclase Activator Activity Identical Protein Binding Negative Regulation Of DNA Metabolic Process Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Activity Ankyrin Repeat Binding Protection From Non-homologous End Joining At Telomere Zinc Ion Binding Regulation Of Phosphorus Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Telomere Localization Meiotic Telomere Clustering Telomeric D-loop Disassembly
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