ZCCHC10 and KPNA3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZCCHC10	KPNA3
Gene Name		zinc finger, CCHC domain containing 10	karyopherin alpha 3 (importin alpha 4)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nuclear Pore Nucleoplasm Cytosol
	Molecular Function	Nucleic Acid Binding Zinc Ion Binding	Protein Binding Protein C-terminus Binding Nuclear Localization Sequence Binding Protein Transporter Activity
	Biological Process		Protein Complex Assembly NLS-bearing Protein Import Into Nucleus Cytokine-mediated Signaling Pathway Viral Entry Into Host Cell Viral Penetration Into Host Nucleus
Pathways			ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS			Menopause (age at onset) ( 22267201) Obesity-related traits ( 23251661)
Protein-Protein Interactions		50 interactors: ARGLU1 BEND7 CEP63 CEP70 COIL CTNNBL1 DAB1 DACH1 DHX8 DPPA2 DZIP3 EEF1A1 EPB41 FAM9B FRA10AC1 IK KCTD6 KPNA3 LNX1 LUC7L2 NUDT14 PCBP1 PIN1 PPIG PRPF3 PRPF38A PRPF40A PRR13 PSME3 PTPN3 RBM39 SART1 SDCBP SDCBP2 SF3B2 SF3B4 SFMBT1 SIAH1 SLU7 SNIP1 SNRPD2 STAC3 STX11 TCEB3B TFCP2 THAP1 TP53 U2AF1 ZBTB14 ZBTB8A	28 interactors: APOL6 CDKN1B COIL DDX21 EPHA2 ERCC3 FAM50B FTL GATA6 GTF2H1 HNRNPC KPNB1 MAT2B MTA1 MVP MYOD1 NFE2L2 NFKB1 NUP50 RCC1 RPRD1A SLC5A11 TEX37 TGM2 TSSC4 ZBTB24 ZCCHC10 ZNF131
Entrez ID		54819	3839
HPRD ID		15699	03536
Ensembl ID		ENSG00000155329	ENSG00000102753
Uniprot IDs		D6R9G7 G3XAM1 Q8TBK6	O00505 Q8IYQ9
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Ribonucleoprotein Complex Assembly Transcription, DNA-templated Spliceosomal SnRNP Assembly RNA Biosynthetic Process Cellular Process Cellular Component Assembly Spliceosomal Complex Assembly Ribonucleoprotein Complex Biogenesis Signal Transduction In Response To DNA Damage Cell Cycle Regulation Of Mitotic Cell Cycle Cellular Macromolecular Complex Assembly Regulation Of Cell Cycle Negative Regulation Of Fibroblast Proliferation Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Maturation Of 5S RRNA DNA Damage Checkpoint MRNA Splice Site Selection Negative Regulation Of Macromitophagy Positive Regulation Of Cytotoxic T Cell Differentiation Cerebellum Structural Organization Oligodendrocyte Apoptotic Process Viral Penetration Into Host Nucleus	Viral Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Response To Organic Substance Nitrogen Compound Metabolic Process Gene Expression Nucleotide-excision Repair, DNA Damage Removal Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Termination Of RNA Polymerase I Transcription Programmed Cell Death Transcription Elongation From RNA Polymerase I Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA Catabolic Process Osteoblast Differentiation Transcription Initiation From RNA Polymerase I Promoter Cell Death Death 7-methylguanosine MRNA Capping Response To Abiotic Stimulus Transcription From RNA Polymerase I Promoter 7-methylguanosine RNA Capping Positive Regulation Of Metabolic Process Regulation Of Gene Expression Transcription-coupled Nucleotide-excision Repair Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Transcription Positive Regulation Of Wound Healing Regulation Of Nucleic Acid-templated Transcription Cellular Response To DNA Damage Stimulus Regulation Of RNA Biosynthetic Process Response To Lipid Response To Estrogen Regulation Of Gene Expression, Epigenetic Negative Regulation Of Interleukin-12 Biosynthetic Process Nucleotide-excision Repair, DNA Duplex Unwinding Notochord Cell Development Regulation Of Cell Cycle Process Cellular Macromolecule Catabolic Process Macromolecule Biosynthetic Process
Tagcloud ?		adcy3 angptl2 annotated beadchip bmi boston boys c18orf8 corrected correction cpg dok2 epigenomic fdr generational humanmethylation27 illumina infant lends maternal mother offspring plac1 prepregnancy prr16 sapcd2 separately stated wnt16	alpha4 ataxias capicua desensitize erk ets etv etv1 etv4 etv5 give highlight hmg importin interconnections mechanistic modulating motivating multisite nls p90 pea3 phosphorylations polyoma relieved represses rsk s6 spinocerebellar
Tagcloud (Difference) ?		adcy3 angptl2 annotated beadchip bmi boston boys c18orf8 corrected correction cpg dok2 epigenomic fdr generational humanmethylation27 illumina infant lends maternal mother offspring plac1 prepregnancy prr16 sapcd2 separately stated wnt16	alpha4 ataxias capicua desensitize erk ets etv etv1 etv4 etv5 give highlight hmg importin interconnections mechanistic modulating motivating multisite nls p90 pea3 phosphorylations polyoma relieved represses rsk s6 spinocerebellar
Tagcloud (Intersection) ?