ZCCHC10 and SLU7

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		ZCCHC10	SLU7
Description		zinc finger CCHC-type containing 10	spliceosome associated SLU7
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Membrane Nuclear Speck Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Second Spliceosomal Transesterification Activity Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding Metal Ion Binding
	Biological Process		RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing Intracellular Protein Transport RNA Splicing Cellular Response To Heat
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045)	Asthma ( 32296059) Common carotid intima-media thickness ( 29206233)
Interacting Genes		55 interacting genes: ANKRD36B ARGLU1 BEND7 CAVIN1 CEP63 CEP70 COIL CTNNBL1 DAB1 DPPA2 DZIP3 EEF1A1 ELOA2 EPB41 FAM9B FRA10AC1 GKAP1 HMGXB4 IK KCTD6 KPNA3 LNX1 LUC7L2 MAB21L3 MEOX1 NUDT14 PCBP1 PIN1 PPIG PRPF3 PRPF38A PRPF40A PRR13 PSME3 PTPN3 RBM39 RPL22 SART1 SDCBP SDCBP2 SF3B2 SF3B4 SFMBT1 SIAH1 SLU7 SNIP1 SNRPD2 STAC3 STX11 TFCP2 THAP1 TP53 U2AF1 ZBTB14 ZBTB8A	29 interacting genes: AIMP2 BAG2 CCDC85B CEP70 DEF6 FHL3 GOLGA2 GTF2I HNRNPA0 IKBKG JMJD6 KDM1A KRT40 LMNA LONRF1 LZTS2 MCC NFKBID NSD3 PCBP2 PIBF1 PPIE PPIG PPIL3 PRMT5 PRMT6 TEPSIN THAP1 ZCCHC10
Entrez ID		54819	10569
HPRD ID		15699	12074
Ensembl ID		ENSG00000155329	ENSG00000164609
Uniprot IDs		B3KVL5 B4DU89 D6R9G7 D6RHC2 G3XAM1 Q8TBK6	O95391
PDB IDs			5XJC 6ICZ 6QDV 7W5A 7W5B 8C6J 9FMD
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions U2-type Precatalytic Spliceosome MRNA Metabolic Process MRNA Processing Spliceosomal Complex Nucleoplasm Nuclear Speck RNA Metabolic Process RNA Processing Protein-RNA Complex Assembly Nucleus Precatalytic Spliceosome Nucleic Acid Metabolic Process RNA Binding U2-type Prespliceosome Assembly Protein Binding Identical Protein Binding U2 SnRNP Nucleobase-containing Compound Metabolic Process Catalytic Step 2 Spliceosome Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Macromolecule Metabolic Process U1 SnRNP Cajal Body U12-type Spliceosomal Complex U2-type Spliceosomal Complex Protein-containing Complex Assembly Pre-mRNA 3'-splice Site Binding RS Domain Binding U4/U6 X U5 Tri-snRNP Complex Cytosol Protein-containing Complex Organization MDM2/MDM4 Family Protein Binding Regulation Of Mitotic Cell Cycle Small Nuclear Ribonucleoprotein Complex MRNA Cis Splicing, Via Spliceosome U2-type Prespliceosome	Nucleoplasm Peptidyl-prolyl Cis-trans Isomerase Activity Histone Methyltransferase Activity Histone H4R3 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone Arginine N-methyltransferase Activity Protein Demethylase Activity Cyclosporin A Binding Protein-arginine N-methyltransferase Activity Golgi Ribbon Formation Transcription Regulator Activator Activity Protein Binding Nucleus Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Chromatin Organization Protein Folding Histone Demethylase Activity Regulation Of Macromolecule Metabolic Process Regulation Of Protein Modification Process Chromatin Remodeling Histone Methyltransferase Complex Regulation Of Gene Expression Cytoskeleton Organization Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Regulation Of Signal Transduction By P53 Class Mediator Histone H4R3 Demethylase Activity Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Peptidyl-lysine 5-dioxygenase Activity Histone H3R2 Demethylase Activity Oxidative RNA Demethylation Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Histone H2AR3 Methyltransferase Activity Primary Ureteric Bud Growth Coated Vesicle Membrane Positive Regulation Of Macromolecule Metabolic Process
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