ZCCHC10 and ZBTB14

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		ZCCHC10	ZBTB14
Name		zinc finger CCHC-type containing 10	zinc finger and BTB domain containing 14
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	None	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	None	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Kidney Development Regulation Of Immune System Process Heart Valve Development Cardiac Septum Development Negative Regulation Of DNA-templated Transcription Coronary Vasculature Development
GWAS		Eyebrow thickness ( 26926045 )	Cerebral amyloid deposition (PET imaging) ( 26252872 ) Lacunar stroke ( 33773637 )
Novel Interactors		1 novel interactors: JADE2	10 novel interactors: AP4B1 ASXL3 B4GALT6 COLEC12 ITGB7 KCNAB3 PLAGL1 PTPN2 SLC4A1 TM9SF1
Interacting Genes		55 interacting genes: ANKRD36B ARGLU1 BEND7 CAVIN1 CEP63 CEP70 COIL CTNNBL1 DAB1 DPPA2 DZIP3 EEF1A1 ELOA2 EPB41 FAM9B FRA10AC1 GKAP1 HMGXB4 IK KCTD6 KPNA3 LNX1 LUC7L2 MAB21L3 MEOX1 NUDT14 PCBP1 PIN1 PPIG PRPF3 PRPF38A PRPF40A PRR13 PSME3 PTPN3 RBM39 RPL22 SART1 SDCBP SDCBP2 SF3B2 SF3B4 SFMBT1 SIAH1 SLU7 SNIP1 SNRPD2 STAC3 STX11 TFCP2 THAP1 TP53 U2AF1 ZBTB14 ZBTB8A	51 interacting genes: AP1M1 ATP5PO ATRIP BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 KAT5 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 OGT PIN1 PNKP POLR2L PRMT1 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SNRPB2 SYT16 TCEANC TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2
Entrez ID		54819	7541
HPRD ID		15699	03674
Ensembl ID		ENSG00000155329	ENSG00000198081
Uniprot IDs		B3KVL5 B4DU89 D6R9G7 D6RHC2 G3XAM1 Q8TBK6	B2R850 O43829
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions U2-type Precatalytic Spliceosome MRNA Metabolic Process MRNA Processing Spliceosomal Complex Nucleoplasm Nuclear Speck RNA Metabolic Process RNA Processing Protein-RNA Complex Assembly Nucleus Precatalytic Spliceosome Nucleic Acid Metabolic Process RNA Binding U2-type Prespliceosome Assembly Protein Binding Identical Protein Binding U2 SnRNP Nucleobase-containing Compound Metabolic Process Catalytic Step 2 Spliceosome Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Macromolecule Metabolic Process U1 SnRNP Cajal Body U12-type Spliceosomal Complex U2-type Spliceosomal Complex Protein-containing Complex Assembly Pre-mRNA 3'-splice Site Binding RS Domain Binding U4/U6 X U5 Tri-snRNP Complex Cytosol Protein-containing Complex Organization MDM2/MDM4 Family Protein Binding Regulation Of Mitotic Cell Cycle Small Nuclear Ribonucleoprotein Complex MRNA Cis Splicing, Via Spliceosome U2-type Prespliceosome	Nucleoplasm Nucleus Macromolecule Metabolic Process Nucleic Acid Metabolic Process Regulation Of Double-strand Break Repair Regulation Of DNA Repair Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Site Of Double-strand Break Protein N-terminal-serine Acetyltransferase Activity Nucleotide-excision Repair Protein Binding DNA Repair Regulation Of Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Stress Recombinational Repair Positive Regulation Of DNA Repair Double-strand Break Repair Double-strand Break Repair Via Homologous Recombination Mismatch Repair NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Protein Acetylation Positive Regulation Of Double-strand Break Repair Positive Regulation Of Mitotic Sister Chromatid Segregation Positive Regulation Of Double-strand Break Repair Via Homologous Recombination G-rich Strand Telomeric DNA Binding RNA Processing MRNA Splicing, Via Spliceosome U2-type Precatalytic Spliceosome N-terminal Protein Amino Acid Acetylation Clathrin Adaptor Complex Organelle Assembly RNA Splicing, Via Transesterification Reactions DNA Replication Factor A Complex Cytoplasmic Translation RNA Metabolic Process DNA Metabolic Process Regulation Of Cell Cycle Process