FAM90A1 and TAX1BP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM90A1	TAX1BP1
Description		family with sequence similarity 90 member A1	Tax1 binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component		Phagophore Assembly Site Cytoplasm Mitochondrion Autophagosome Cytosol Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Kinase Binding Protein-macromolecule Adaptor Activity Signaling Adaptor Activity Metal Ion Binding
	Biological Process		Immune System Process Cytoplasmic Pattern Recognition Receptor Signaling Pathway Autophagy Apoptotic Process Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Protein K48-linked Ubiquitination Protein Localization To Phagocytic Vesicle Negative Regulation Of Interleukin-1-mediated Signaling Pathway
Pathways			Regulation of TNFR1 signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Gut microbiota (functional units) ( 27694959)	Adventurousness ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Allergic rhinitis ( 30013184) Asthma ( 31959851) Asthma (childhood onset) ( 31036433) Hypospadias ( 25108383) Metabolite levels ( 23823483)
Interacting Genes		162 interacting genes: ABI2 ACTN3 AKAP9 AMOTL2 ANKRD23 ANKRD29 AP2M1 APP ARHGEF9 ARRDC3 BANP BCAR1 BEGAIN BLZF1 CADPS CALCOCO2 CARD9 CCDC13 CCDC57 CCN3 CCNC CCNL2 CDR2 CEP55 CEP70 CEP72 CEP76 CHRDL2 COG6 CYSRT1 DTX3 DVL2 DVL3 EFEMP2 ENKD1 EXOSC8 FAM228A FHL3 FLACC1 FLOT1 FOSB FSD2 FXR1 FXR2 FYN GABPB1 GCSAML GNPTAB GOLGA2 GOPC GPRASP3 GPSM1 GRIPAP1 HAND2 HMBOX1 HOMER3 HOMEZ HOOK2 HSF2BP ISY1 KANK2 KASH5 KIFC3 KLHL12 KPNA6 KRT31 KRT34 KRT38 KRT40 KRTAP1-1 KRTAP10-8 LDOC1 LHX6 LIMS1 LMO2 LNX1 LRP2BP LRRK2 LZTS1 LZTS2 MAD1L1 MDFI MEIS3 MID2 MIPOL1 MLH1 MORN3 MSS51 MTUS2 MYOG NBPF19 NDUFB7 NOTCH2NLA NUDT21 OVOL1 PBX1 PBX2 PDLIM7 PFDN5 PICK1 PIH1D1 PLAGL2 POF1B PPARA PPP1R13B PRDM6 PRKAR1B PRR23B PSME3 PSTPIP1 RAB11FIP2 RABEP1 RBM48 REL RHOH RINT1 ROPN1 RPRD1A SH2B2 SIAH1 SMAD3 SMARCB1 SNW1 SPRED1 SRPK2 STAC3 STMN2 STX11 TAX1BP1 TEPSIN TFIP11 TLE5 TMCC2 TRAF2 TRAF4 TRIB3 TRIM23 TRIM27 TRIM42 TRIM54 TRIM55 TRIM69 TRIM9 TRIML2 VRTN VWC2 ZBTB14 ZBTB16 ZBTB7B ZBTB8A ZC2HC1C ZMYND12 ZNF143 ZNF212 ZNF343 ZNF526 ZNF581 ZNF655 ZNF688 ZNF76 ZRANB1 ZWINT	72 interacting genes: ARHGAP1 ARK2N AZI2 CBX8 COG7 CWF19L2 CXXC1 DAXX DAZAP2 DSTN ENTREP1 FAM161A FAM168A FAM90A1 FOXC2 GABARAP GABARAPL1 GABARAPL2 IGFN1 IKBKG KANK2 KAT5 KIF5B L3MBTL2 LITAF LMO3 LNX1 LRATD2 MAP1LC3C MRPL11 MRPL53 MYO6 NMRK1 NTAQ1 ORC5 PIBF1 PLEKHB2 PLEKHN1 POLR1C RAB18 RAD18 RAD23B RAD54L2 RIPK1 RNF11 RNF26 SCNM1 SH3GLB1 SSX2 STARD13 TBC1D15 TBC1D17 TCAF1 TCEA2 TCL1A TNFAIP3 TNIP3 TRAF4 TRAF6 TRAPPC6A TRIM14 TRIM45 TSEN2 TSG101 TSHZ3 UBA52 UBASH3A UBB UBC UBTFL1 USP2 ZNF446
Entrez ID		55138	8887
HPRD ID		07672	05618
Ensembl ID		ENSG00000171847	ENSG00000106052
Uniprot IDs		Q86YD7	B4DSG5 Q86VP1
PDB IDs			2M7Q 4BMJ 4NLH 4Z4K 4Z4M 5AAS 5YT6 5Z7G 8W6A 8W6B
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding Zinc Ion Binding Cytoplasm Cytoskeleton Organization Regulation Of Intracellular Signal Transduction Supramolecular Fiber Organization DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Organelle Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Ubiquitin Protein Ligase Activity Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Signal Transduction TORC1 Complex Assembly Cytoskeleton Signaling Adaptor Activity Protein Homodimerization Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Protein Ubiquitination Keratin Filament Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Transcription By RNA Polymerase II Protein Kinase Binding	Ubiquitin Protein Ligase Binding Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Protein Binding Autophagosome Autophagosome Maturation Protein-containing Complex Disassembly Autophagosome Membrane Cytoplasm Modification-dependent Protein Catabolic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Polyubiquitin Modification-dependent Protein Binding Macromolecule Catabolic Process Endosome Membrane Proteolysis Involved In Protein Catabolic Process Protein Tag Activity Autophagy GABA Receptor Binding Autophagosome Assembly Regulation Of Canonical NF-kappaB Signal Transduction Macroautophagy Autophagosome Organization Mitophagy Ubiquitin Protein Ligase Activity Cellular Response To Starvation WW Domain Binding Post-translational Protein Modification Protein Ubiquitination Autophagy Of Mitochondrion Catabolic Process Regulation Of Protein Modification Process Signaling Adaptor Activity Response To Starvation Protein Modification Process Proteolysis Ubiquitin-dependent Protein Catabolic Process Regulation Of Macromolecule Metabolic Process Protein Modification By Small Protein Conjugation Beta-tubulin Binding Regulation Of Primary Metabolic Process Cellular Response To Nutrient Levels Organelle Assembly Vacuole Organization Identical Protein Binding Zinc Ion Binding Cytosol Positive Regulation Of Protein Modification Process
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