FAM90A1 and FOSB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM90A1	FOSB
Description		family with sequence similarity 90 member A1	FosB proto-oncogene, AP-1 transcription factor subunit
Image		No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Response To Amphetamine Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Female Pregnancy Response To Xenobiotic Stimulus Response To Mechanical Stimulus Response To Progesterone Cellular Response To Hormone Stimulus Response To Nicotine Response To Cocaine Response To Morphine Response To Ethanol Positive Regulation Of Transcription By RNA Polymerase II Behavioral Response To Cocaine Response To Corticosterone Response To CAMP Cellular Response To Calcium Ion
Pathways			Estrogen-dependent gene expression NGF-stimulated transcription NGF-stimulated transcription Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS		Gut microbiota (functional units) ( 27694959)	Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Heel bone mineral density ( 28869591 30598549)
Interacting Genes		162 interacting genes: ABI2 ACTN3 AKAP9 AMOTL2 ANKRD23 ANKRD29 AP2M1 APP ARHGEF9 ARRDC3 BANP BCAR1 BEGAIN BLZF1 CADPS CALCOCO2 CARD9 CCDC13 CCDC57 CCN3 CCNC CCNL2 CDR2 CEP55 CEP70 CEP72 CEP76 CHRDL2 COG6 CYSRT1 DTX3 DVL2 DVL3 EFEMP2 ENKD1 EXOSC8 FAM228A FHL3 FLACC1 FLOT1 FOSB FSD2 FXR1 FXR2 FYN GABPB1 GCSAML GNPTAB GOLGA2 GOPC GPRASP3 GPSM1 GRIPAP1 HAND2 HMBOX1 HOMER3 HOMEZ HOOK2 HSF2BP ISY1 KANK2 KASH5 KIFC3 KLHL12 KPNA6 KRT31 KRT34 KRT38 KRT40 KRTAP1-1 KRTAP10-8 LDOC1 LHX6 LIMS1 LMO2 LNX1 LRP2BP LRRK2 LZTS1 LZTS2 MAD1L1 MDFI MEIS3 MID2 MIPOL1 MLH1 MORN3 MSS51 MTUS2 MYOG NBPF19 NDUFB7 NOTCH2NLA NUDT21 OVOL1 PBX1 PBX2 PDLIM7 PFDN5 PICK1 PIH1D1 PLAGL2 POF1B PPARA PPP1R13B PRDM6 PRKAR1B PRR23B PSME3 PSTPIP1 RAB11FIP2 RABEP1 RBM48 REL RHOH RINT1 ROPN1 RPRD1A SH2B2 SIAH1 SMAD3 SMARCB1 SNW1 SPRED1 SRPK2 STAC3 STMN2 STX11 TAX1BP1 TEPSIN TFIP11 TLE5 TMCC2 TRAF2 TRAF4 TRIB3 TRIM23 TRIM27 TRIM42 TRIM54 TRIM55 TRIM69 TRIM9 TRIML2 VRTN VWC2 ZBTB14 ZBTB16 ZBTB7B ZBTB8A ZC2HC1C ZMYND12 ZNF143 ZNF212 ZNF343 ZNF526 ZNF581 ZNF655 ZNF688 ZNF76 ZRANB1 ZWINT	28 interacting genes: AGXT CENPO CREB5 CYTH4 DNMT3L ENKD1 EP300 FAM222B FAM90A1 FOXP3 GLIS2 JUNB JUND LINC00963 NCK2 NEDD9 NFE2L2 PHC2 PHF1 POGZ POU6F2 ROR2 SRA1 TENT5B TLE5 TLX3 VEZF1 ZC3H10
Entrez ID		55138	2354
HPRD ID		07672	01270
Ensembl ID		ENSG00000171847	ENSG00000125740
Uniprot IDs		Q86YD7	P53539
PDB IDs			5VPA 5VPB 5VPC 5VPD 5VPE 5VPF 6UCI 6UCL 6UCM 7UCC 7UCD
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding Zinc Ion Binding Cytoplasm Cytoskeleton Organization Regulation Of Intracellular Signal Transduction Supramolecular Fiber Organization DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Organelle Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Ubiquitin Protein Ligase Activity Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Signal Transduction TORC1 Complex Assembly Cytoskeleton Signaling Adaptor Activity Protein Homodimerization Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Protein Ubiquitination Keratin Filament Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Transcription By RNA Polymerase II Protein Kinase Binding	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of T-helper 17 Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Chromatin Regulation Of T-helper 17 Type Immune Response Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Factor AP-1 Complex Transcription Coregulator Binding Protein-DNA Complex DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Regulation Of T-helper Cell Differentiation DNA-binding Transcription Factor Activity Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Negative Regulation Of RNA Metabolic Process ESC/E(Z) Complex Sequence-specific Double-stranded DNA Binding Regulation Of CD4-positive, Alpha-beta T Cell Activation Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Activation CD4-positive, Alpha-beta T Cell Lineage Commitment Regulation Of Cell Differentiation Zinc Ion Binding Alpha-beta T Cell Lineage Commitment CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Alpha-beta T Cell Activation Negative Regulation Of Macromolecule Metabolic Process L-serine-pyruvate Transaminase Activity T Cell Lineage Commitment
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