MRPL20 and TP53BP2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MRPL20	TP53BP2
Gene Name		mitochondrial ribosomal protein L20	tumor protein p53 binding protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Ribosome	Nucleus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Structural Constituent Of Ribosome Protein Binding RRNA Binding Poly(A) RNA Binding	SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding Identical Protein Binding NF-kappaB Binding
	Biological Process	Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination	Cell Cycle Signal Transduction Central Nervous System Development Heart Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Signal Transduction Response To Ionizing Radiation Negative Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways		Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ACP1 APP CALM2 CAPZB DUSP23 EPS8 ITSN1 OXA1L TP53BP2 USP13	58 interactors: APP ATPAF2 ATXN7 BAIAP2 BCL2 BCL2L1 CCDC92 CSNK2B CWF19L2 DCUN1D1 EEF1A1 GRB2 HIST1H2BC HNRNPUL1 KIF5A LMO4 MAGI1 MAPK8IP2 MRPL20 MTMR14 NAE1 NDC80 NUTM1 OTUB2 PLEKHN1 PLK1 POLR2L PPHLN1 PPP1CA PPP1CB PPP1CC PRKAB2 PRPF31 PTN RELA SIAH1 SIAH2 SSX2IP SUMO2 SUMO3 TANK TBC1D22B TCL1A TP53 TRAF4 TXLNA UBASH3A UNC119 USP4 UTP14A WWP1 WWP2 YAP1 YES1 YWHAG YWHAQ ZGPAT ZNF26
Entrez ID		55052	7159
HPRD ID		14746	11803
Ensembl ID		ENSG00000242485	ENSG00000143514
Uniprot IDs		B7Z746 Q9BYC9	Q13625
PDB IDs			1YCS 2UWQ 4A63
Enriched GO Terms of Interacting Partners?		Barbed-end Actin Filament Capping Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Regulation Of Signal Transduction Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Platelet Degranulation Regulation Of Oxidoreductase Activity Negative Regulation Of Protein Polymerization Blood Coagulation Regulation Of Signaling Negative Regulation Of Protein Complex Disassembly Hemostasis Response To Radiation Regulation Of Protein Depolymerization Synaptic Growth At Neuromuscular Junction Mitochondrial Proton-transporting ATP Synthase Complex Assembly Adult Locomotory Behavior Regulation Of Protein Complex Disassembly Negative Regulation Of Protein Complex Assembly Actin Polymerization-dependent Cell Motility Collateral Sprouting In Absence Of Injury Nervous System Development Regulation Of Body Fluid Levels Proton-transporting ATP Synthase Complex Assembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Wound Healing Negative Regulation Of Cytoskeleton Organization Collateral Sprouting Axon Midline Choice Point Recognition Epidermal Growth Factor Receptor Signaling Pathway Adult Behavior ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Peptidyl-tyrosine Dephosphorylation Regulation Of Actin Filament Polymerization Movement Of Cell Or Subcellular Component Negative Regulation Of Filopodium Assembly Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of High Voltage-gated Calcium Channel Activity Response To Wounding Exit From Mitosis Axon Choice Point Recognition Platelet Activation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of ATPase Activity	Neuron Death Neuron Apoptotic Process Response To Radiation Regulation Of Signal Transduction Regulation Of Signaling Response To External Stimulus Negative Regulation Of Signal Transduction Entrainment Of Circadian Clock By Photoperiod Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Signaling Photoperiodism Entrainment Of Circadian Clock Positive Regulation Of Apoptotic Signaling Pathway Cell Part Morphogenesis Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Phosphorylation Response To Light Stimulus Protein Modification By Small Protein Conjugation Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Cycle Neuron Projection Morphogenesis Regulation Of Mitochondrion Organization Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cell Projection Morphogenesis Axonogenesis Cellular Protein Modification Process Positive Regulation Of Signal Transduction Regulation Of Protein Phosphorylation Regulation Of Phosphorus Metabolic Process Cell Morphogenesis Regulation Of Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Regulation Of Cellular Protein Metabolic Process Response To Gamma Radiation Axon Development Regulation Of Extrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Generation Of Neurons Nervous System Development Cellular Response To Ionizing Radiation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Mitochondrion Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Innate Immune Response Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Neuron Projection Development Neurogenesis Anatomical Structure Morphogenesis
Tagcloud ?		capza1 cgh cghs cnv coherent col20a1 csde1 csnk1e dennd2d derive discerning discriminative gpr18 han hbxip identifiable ikzf1 mcoln2 microarrays rcan3 rwdd3 scrn1 signatures statuses supervised taiwanese trim45 wars2 zmym6	adenovirus angiotensin apoptosis array at2r bag3 bmp6 bmp7 bnipi cytokine downregulation du145 gadd45a hrk il6 il8 mapk microrna next numerous p44 pc r2 silence sirnas tnfsf10 trail transduced utilized
Tagcloud (Difference) ?		capza1 cgh cghs cnv coherent col20a1 csde1 csnk1e dennd2d derive discerning discriminative gpr18 han hbxip identifiable ikzf1 mcoln2 microarrays rcan3 rwdd3 scrn1 signatures statuses supervised taiwanese trim45 wars2 zmym6	adenovirus angiotensin apoptosis array at2r bag3 bmp6 bmp7 bnipi cytokine downregulation du145 gadd45a hrk il6 il8 mapk microrna next numerous p44 pc r2 silence sirnas tnfsf10 trail transduced utilized
Tagcloud (Intersection) ?