PPP1R2 and TINF2

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		PPP1R2	TINF2
Gene Name		protein phosphatase 1, regulatory (inhibitor) subunit 2	TERF1 (TRF1)-interacting nuclear factor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Perinucleolar Chromocenter Nuclear Matrix
	Molecular Function	Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding	DNA Binding Protein Binding Telomeric DNA Binding
	Biological Process	Glycogen Metabolic Process Generation Of Precursor Metabolites And Energy Regulation Of Signal Transduction Negative Regulation Of Catalytic Activity Regulation Of Phosphoprotein Phosphatase Activity	Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Protein ADP-ribosylation Telomere Assembly Positive Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome Negative Regulation Of Epithelial Cell Proliferation Protein Localization To Chromosome, Telomeric Region
Pathways			Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CDK5 CSNK2A1 CSNK2A2 GSK3B LMTK2 NEK2 PPP1CA PPP1CC PPP1R9A PPP1R9B TERF2IP TINF2	88 interactors: ACD ACOT7 ACTB ADA AFAP1L2 AIPL1 AK1 ANKMY2 ANXA4 ANXA5 APOBEC3F APPL2 ARHGDIA ARID3B BAG3 BIN2 CALD1 CCDC43 CCDC9 CKB CLK3 CPNE3 CRYGS CTTN DBN1 DCX DHFRL1 DPP3 EEF1D EIF4B ENO2 FAM131B FERMT3 FKBP6 GAPDH GNMT HNMT HOXA3 HSP90AB1 IPO5 KCTD17 LASP1 LDHA LGALSL LTA4H MAP2K3 NCDN NOL3 NUDC NUDCD2 OR2H1 PAGE2 PAK1IP1 PEX5 PFKP PGM1 PGM2 PHPT1 PKM POT1 PPP1R2 PPP6R3 PRKCB REM2 RGS14 RPSA SARS SCRN2 SIAH2 STUB1 SULT1C2 TAGLN TBL1X TERF1 TERF2 TOMM34 TPP1 TRIM15 TRIM16 TRIP10 TUBB TUBB4B TXNDC17 UCHL1 VIPR1 YWHAG ZFP36L1 ZNF790
Entrez ID		5504	26277
HPRD ID		03478	16056
Ensembl ID		ENSG00000184203	ENSG00000092330
Uniprot IDs		P41236 Q6NXS2	B4DFJ1 Q9BSI4
PDB IDs			3BQO 3BU8
Enriched GO Terms of Interacting Partners?		Regulation Of Organelle Organization Cell Cycle Negative Regulation Of Chromosome Organization Rhythmic Process Regulation Of Mitotic Nuclear Division Regulation Of Cellular Component Organization Neuron Projection Development Regulation Of Cell Cycle Process Regulation Of Chromosome Organization Protein Localization To Chromosome, Telomeric Region Neuron Development Glycogen Metabolic Process Regulation Of Cell Division Neuron Differentiation Response To External Stimulus Negative Regulation Of Telomere Maintenance Polysaccharide Metabolic Process Regulation Of Chromosome Segregation Cell Projection Organization Phosphate-containing Compound Metabolic Process Protein Phosphorylation Regulation Of Cell Growth Regulation Of Signaling Peptidyl-serine Phosphorylation Negative Regulation Of Cellular Protein Metabolic Process Axon Guidance Cellular Protein Modification Process Regulation Of Telomere Maintenance Regulation Of Mitotic Cell Cycle Energy Reserve Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Division Negative Regulation Of Protein Metabolic Process Triglyceride Catabolic Process Generation Of Neurons Regulation Of Carbohydrate Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Entrainment Of Circadian Clock By Photoperiod Neurogenesis Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Circadian Rhythm Cell Cycle Process Protein Localization To Chromosome Axonogenesis Telomere Maintenance Via Telomere Lengthening Regulation Of Protein Export From Nucleus Regulation Of Proteasomal Protein Catabolic Process	Negative Regulation Of Telomere Maintenance Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Glycolytic Process Protection From Non-homologous End Joining At Telomere Carbohydrate Catabolic Process Negative Regulation Of DNA Replication Telomere Assembly Catabolic Process Negative Regulation Of DNA Metabolic Process Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Catalytic Activity Positive Regulation Of Telomerase Activity Pyruvate Metabolic Process Telomere Maintenance Telomere Maintenance Via Telomerase Pathogenesis Generation Of Precursor Metabolites And Energy Glucose Metabolic Process Positive Regulation Of Single-stranded Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of Chromosome Organization Small Molecule Metabolic Process Organic Acid Metabolic Process Regulation Of DNA Biosynthetic Process Regulation Of Catalytic Activity Carboxylic Acid Metabolic Process Age-dependent Telomere Shortening Telomeric Loop Formation Nervous System Development Regulation Of Signaling Positive Regulation Of DNA Biosynthetic Process Glycogen Metabolic Process RNA-dependent DNA Replication Nucleoside Metabolic Process Telomere Maintenance Via Telomere Shortening Regulation Of Signal Transduction Hexose Metabolic Process Cellular Process Regulation Of DNA Replication Monocarboxylic Acid Metabolic Process Cellular Carbohydrate Metabolic Process Response To Stimulus Protein Localization To Chromosome Organelle Organization Telomere Maintenance Via Telomere Lengthening Polysaccharide Metabolic Process
Tagcloud ?		a375 abrogating augmentation benzodiazepines calyculin contrasted dephosphorylates fmk haematological hdac6 hdaci hybridizing hybrids hypophos mechanistically melanin melanocytes offering oxamflatin phorylated pig1 prompted prospects rising saha shuffling timp vad	acd add broader clustered clustering convincingly correction cosegregated ends families fisher germline inactivating lod logarithm melanoma nonsense pot1 predispose probands q320x r364x shelterin tailed terf1 terf2 terf2ip yates
Tagcloud (Difference) ?		a375 abrogating augmentation benzodiazepines calyculin contrasted dephosphorylates fmk haematological hdac6 hdaci hybridizing hybrids hypophos mechanistically melanin melanocytes offering oxamflatin phorylated pig1 prompted prospects rising saha shuffling timp vad	acd add broader clustered clustering convincingly correction cosegregated ends families fisher germline inactivating lod logarithm melanoma nonsense pot1 predispose probands q320x r364x shelterin tailed terf1 terf2 terf2ip yates
Tagcloud (Intersection) ?