CHCHD3 and CCDC85B

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		CHCHD3	CCDC85B
Gene Name		coiled-coil-helix-coiled-coil-helix domain containing 3	coiled-coil domain containing 85B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm Centrosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Phosphatase Binding Protein Complex Scaffold	Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Inner Mitochondrial Membrane Organization Mitochondrial Fusion	Transcription, DNA-templated Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: BLZF1 CALCOCO2 CCDC33 CCDC85B FANCL GMCL1P1 GOLGA2 KRT40 KRTAP4-12 LZTS2 NOTCH2NL NUDT3 PDE4DIP RAB3IP RPGRIP1 SAMM50 SPAG5 SPERT SSX2IP TRAF1 TRIM27 USHBP1	133 interactors: AGGF1 AKAP17A AKIRIN2 ALS2CR11 APEX2 AQP1 BEX2 C10orf10 C19orf25 C1orf111 C20orf195 C21orf91 C7orf50 C8orf48 CARD9 CCDC112 CCDC116 CCDC120 CCDC185 CCDC33 CCDC67 CCNK CDK18 CDKN1A CEP70 CFAP53 CHCHD3 COPS4 CWC25 DOK5 DTNB DUSP13 EIF3H ENKD1 EPS8 EXOC7 EXOC8 EZH2 FAM107A FAM124B FAM13C FAM208B FAM214B FAM27E3 FAM50B FAM74A4 FASTKD5 FBF1 FCHSD2 FXR2 GCC1 GFI1B GPANK1 HMG20B HNRNPC IKZF5 KANSL1 KIAA0408 KRT17 KRT18 KRT20 KRT6A LDOC1 LMO3 LNX1 LZTS2 MBIP MCM10 MCRS1 MEAF6 MOAP1 MOB1A MOB4 NDUFA5 NEK6 NGFRAP1 NIF3L1 NRIP1 NUP54 PBXIP1 PIDD1 PKN1 PLEKHF2 PLOD3 POLR2L PRC1 PRPF3 PSMA1 PSMC1 PSMC6 PSMF1 RALYL RBM41 RBM7 RIBC2 RNF8 SCNM1 SETD5 SF3A3 SIX1 SLU7 SMARCD1 SYT17 SYTL4 TCEANC TCHP TEAD4 THAP7 TNNI1 TNNT1 TSPYL4 TTC14 TTC25 TUBGCP4 USP2 UTP14A UTP6 VPS72 ZBTB16 ZBTB5 ZC2HC1C ZFC3H1 ZFP36 ZNF165 ZNF205 ZNF250 ZNF337 ZNF417 ZNF426 ZNF564 ZNF638 ZNF764 ZNF821
Entrez ID		54927	11007
HPRD ID		13044	16101
Ensembl ID		ENSG00000106554	ENSG00000175602
Uniprot IDs		A4D1N4 G3V1K1 Q9NX63	Q15834
PDB IDs
Enriched GO Terms of Interacting Partners?		Golgi To Plasma Membrane Transport Intracellular Transport Establishment Of Protein Localization To Membrane Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Cytoplasmic Transport Cellular Component Assembly Negative Regulation Of Interleukin-2 Secretion Mitotic Cell Cycle Post-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Protein Localization To Membrane	Gene Expression RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Cycle RNA Biosynthetic Process Transcription, DNA-templated Mitotic Cell Cycle Process Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Regulation Of Cell Cycle Arrest Regulation Of Gene Expression Signal Transduction Involved In Cell Cycle Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Mitotic G1 DNA Damage Checkpoint Organelle Organization Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Metabolic Process Positive Regulation Of Cell Cycle Arrest Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Apoptotic Process Macromolecule Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Process Programmed Cell Death DNA Damage Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition RNA Processing Mitotic DNA Integrity Checkpoint Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Cell Death
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