PIK3CA and RPS6KB1

  • Number of citations of the paper that reports this interaction (PMID 11279232)
  • 16
  • Data Source:
  • HPRD (in vivo, in vitro)

PIK3CA

RPS6KB1

Gene Name phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ribosomal protein S6 kinase, 70kDa, polypeptide 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 43 interactors: ADAP1 AMBP APLP2 APPL1 ATPIF1 ATR DDX5 DNAJB6 FASLG FTL GABRB1 GNAQ GRIN2B HRAS IL3 IRS2 IRS4 ITIH1 KRAS LCK MRAS NEDD9 NRAS PDE4D PDGFRB PIK3R1 PIK3R3 PRKCD RASD2 RASGRP3 RPS20 RPS6KB1 SGK1 SH3KBP1 SLC9A3R1 SLC9A3R2 SMAD2 SMAD3 SQSTM1 STAT1 TICAM1 UFD1L VARS2 54 interactors: ACTA1 AKT1 APP BTK CDC42 CDK1 CLEC3B COASY CSNK2A1 CSNK2B DPPA4 EEF2K EIF4B EIF4EBP1 EP300 GDI2P1 HTT IRS1 KAT2B KIR3DL1 LYN MAPK1 MAPK3 MAPK8 MAPK9 MAPT MLST8 MTOR MXD1 NCBP1 NEDD4 NEK6 NR1I2 PDK1 PDPK1 PIK3CA PIN1 POLDIP3 PPP1R9A PPP1R9B PPP2CA RAC1 RBX1 RHEB RICTOR RPS6 RPTOR SRC STK11 SYK TERT TRAF4 URI1 XPO1
Entrez ID 5290 6198
HPRD ID 01382 10202
Ensembl ID ENSG00000108443
Uniprot IDs P42336 B2R779 B4DLT4 B4DTG1 F6UYM1 P23443 Q7Z721
PDB IDs 2ENQ 2RD0 3HHM 3HIZ 3ZIM 3A60 3A61 3A62 4L3J 4L3L 4L42 4L43 4L44 4L45 4L46
Enriched GO Terms of Interacting Partners?
Tagcloud ?
amplified  biomarker  e542k  e545d  e545k  embedded  fixed  formalin  h1047l  h1047r  homolog  metastatic  namely  next  oncogenic  paraffin  phospho  phosphoinositol  pi3k  pras40thr246  proline  pten  reflect  refractory  respond  retrospectively  tensin  trastuzumab  unlikely 
70kda  ablation  amp  ampk  aortas  apoe  apolipoprotein  arg2  arginase  atherogenesis  atherosclerosis  atherosclerotic  autophagy  crosstalk  h160f  impairs  interested  mtorc1  mtorc2  nonsenescent  polypeptide  prkaa  replicative  rictor  s6k1  senescent  ureahydrolase  wk 
Tagcloud (Difference) ?
amplified  biomarker  e542k  e545d  e545k  embedded  fixed  formalin  h1047l  h1047r  homolog  metastatic  namely  next  oncogenic  paraffin  phospho  phosphoinositol  pi3k  pras40thr246  proline  pten  reflect  refractory  respond  retrospectively  tensin  trastuzumab  unlikely 
70kda  ablation  amp  ampk  aortas  apoe  apolipoprotein  arg2  arginase  atherogenesis  atherosclerosis  atherosclerotic  autophagy  crosstalk  h160f  impairs  interested  mtorc1  mtorc2  nonsenescent  polypeptide  prkaa  replicative  rictor  s6k1  senescent  ureahydrolase  wk 
Tagcloud (Intersection) ?