POLE and TOPBP1

  • Number of citations of the paper that reports this interaction (PMID 11395493)
  • 65
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

POLE

TOPBP1

Gene Name polymerase (DNA directed), epsilon, catalytic subunit topoisomerase (DNA) II binding protein 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 12 interactors: GINS4 MDM2 PCNA POLA1 POLD4 POLE2 POLE3 POLE4 RAD17 STK19 TOPBP1 XRCC5 19 interactors: ABL1 AKT1 ATM BLM BMPR2 BRIP1 CHEK1 CLSTN1 E2F1 PML POLE PPP1CC RAD9A TBC1D4 TCFL5 TICRR TOP2B UBR5 ZBTB17
Entrez ID 5426 11073
HPRD ID 07177 09678
Ensembl ID ENSG00000177084 ENSG00000163781
Uniprot IDs F5H1D6 Q07864 A0AV47 A7E2X7 Q05BV8 Q92547
PDB IDs 1WF6 2XNH 2XNK 3AL2 3AL3 3JVE 3OLC 3PD7 3UEN 3UEO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
absolute  bfgf  bmp  cdnas  disruption  dorsal  embryo  embryogenesis  explants  fate  globin  helix  hematopoietic  inductive  lineages  marginal  mesoderm  myod  organogenesis  participates  patterning  progenitors  requirement  scl  specify  specifying  ventral  xenopus  zone 
abrogates  atr  bona  checkpoint  chk1  clamp  claspin  damaging  extensively  fide  heterotetrameric  hus1  impacting  irradiation  lac  laco  lacr  lastly  localizes  onto  orphan  portion  rad1  rad9  repeats  repressor  rhino  tethering  uv 
Tagcloud (Difference) ?
absolute  bfgf  bmp  cdnas  disruption  dorsal  embryo  embryogenesis  explants  fate  globin  helix  hematopoietic  inductive  lineages  marginal  mesoderm  myod  organogenesis  participates  patterning  progenitors  requirement  scl  specify  specifying  ventral  xenopus  zone 
abrogates  atr  bona  checkpoint  chk1  clamp  claspin  damaging  extensively  fide  heterotetrameric  hus1  impacting  irradiation  lac  laco  lacr  lastly  localizes  onto  orphan  portion  rad1  rad9  repeats  repressor  rhino  tethering  uv 
Tagcloud (Intersection) ?