SNTG1 and DGKZ

Number of citations of the paper that reports this interaction (PubMedID 11352924)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		SNTG1	DGKZ
Description		syntrophin gamma 1	diacylglycerol kinase zeta
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Ruffle Membrane	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Nuclear Speck Lamellipodium Cell Projection Glutamatergic Synapse
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding	Nucleotide Binding Lipid Kinase Activity ATP-dependent Diacylglycerol Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Metal Ion Binding Alkylglycerol Kinase Activity
	Biological Process	Cell Communication	Lipid Metabolic Process Phosphatidic Acid Biosynthetic Process Signal Transduction Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Cell Migration Platelet Activation Mitotic G1 DNA Damage Checkpoint Signaling Intracellular Signal Transduction Diacylglycerol Metabolic Process Glycerolipid Metabolic Process Lipid Phosphorylation Negative Regulation Of T Cell Receptor Signaling Pathway
Pathways			Effects of PIP2 hydrolysis
Drugs			alpha-Tocopherol succinate
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Age at first sexual intercourse ( 34211149) Diastolic blood pressure ( 27841878) General risk tolerance (MTAG) ( 30643258) Interleukin-6 levels ( 22205395) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Pulmonary function ( 17903307) Pulse pressure ( 27841878) Remission after SSRI treatment in MDD or openness ( 29559929) Response to SSRI in MDD or openness ( 29559929) Superior frontal gyrus grey matter volume ( 25335168) Systolic blood pressure ( 27841878 30578418)	Age at first sexual intercourse ( 34211149) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Body size at age 10 ( 32376654) Immunoglobulin A ( 20694011) Reaction time ( 29844566) Schizophrenia ( 28991256 29483656)
Interacting Genes		16 interacting genes: ADRA1D DGKZ DMD DTNA DTNB FGF2 KCNA4 PLEKHA1 PLEKHA2 SNAP23 STXBP3 TGFBR1 UBC VANGL2 VPS45 VTN	19 interacting genes: DMD HRAS LEPR MAPK6 PLCG1 POLR2M PRKCA RASGRP1 RB1 RBL1 RBL2 SAT1 SNTA1 SNTB1 SNTB2 SNTG1 SNX27 SRC TP53
Entrez ID		54212	8525
HPRD ID		16373	03260
Ensembl ID		ENSG00000147481	ENSG00000149091
Uniprot IDs		A0A2R8Y5T2 A0A2R8Y631 B2RA84 Q9NSN8	Q13574
PDB IDs		7PC7 7PC8 7QQN	5ELQ
Enriched GO Terms of Interacting Partners?		Angiogenesis Involved In Coronary Vascular Morphogenesis Plasma Membrane PDZ Domain Binding Wound Healing Specific Granule Membrane Cell-cell Signaling Signaling Cell Communication Phosphatidylinositol-3,4-bisphosphate Binding Alpha1-adrenergic Receptor Activity Striated Muscle Contraction Lateral Plasma Membrane Animal Organ Development Growth Factor Dependent Regulation Of Skeletal Muscle Satellite Cell Proliferation Regulation Of Cardiac Muscle Cell Proliferation Endothelial Cell Proliferation Regulation Of Animal Organ Morphogenesis Response To Wortmannin Positive Regulation Of Inner Ear Receptor Cell Differentiation Negative Regulation Of Wound Healing Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Tube Morphogenesis Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Retinal Cell Programmed Cell Death Cell Migration Animal Organ Morphogenesis Response To Wounding Lymphatic Endothelial Cell Migration Regulation Of Heart Growth Positive Regulation Of Cell Fate Specification Positive Regulation Of Lens Fiber Cell Differentiation Regulation Of Stem Cell Proliferation Endothelial Cell Migration Positive Regulation Of Inner Ear Auditory Receptor Cell Differentiation Cell Motility Positive Regulation Of Stem Cell Proliferation Corticotropin Hormone Secreting Cell Differentiation Syntaxin Binding Tertiary Granule Muscle Tissue Morphogenesis Post-embryonic Development Roof Of Mouth Development Proepicardium Development Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Transforming Growth Factor Beta Ligand-receptor Complex Symbiont-containing Vacuole Smooth Muscle Cell-matrix Adhesion Rough Endoplasmic Reticulum Lumen	Dystrophin-associated Glycoprotein Complex Syntrophin Complex Regulation Of Lipid Kinase Activity Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition Intracellular Signaling Cassette Ras Protein Signal Transduction Regulation Of Tissue Remodeling Glial Cell Proliferation Regulation Of Kinase Activity Protein-containing Complex Glial Cell Apoptotic Process Regulation Of Bone Remodeling Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Structural Molecule Activity Actin Binding Regulation Of Cell Cycle G1/S Phase Transition Intracellular Signal Transduction Promoter-specific Chromatin Binding Nitric-oxide Synthase Binding Negative Regulation Of Mitotic Cell Cycle Regulation Of Phosphorylation Negative Regulation Of Cell Cycle Phase Transition Diacylglycerol Binding Transcription Regulator Complex Positive Regulation Of Macrophage Differentiation Negative Regulation Of Glial Cell Proliferation Small GTPase-mediated Signal Transduction Ruffle Membrane Regulation Of Mitotic Cell Cycle Regulation Of Heart Rate Negative Regulation Of Cell Cycle Process Regulation Of ERK1 And ERK2 Cascade Neuron Apoptotic Process Sarcolemma Regulation Of Macrophage Differentiation Positive Regulation Of Developmental Process Disordered Domain Specific Binding Cellular Response To Gamma Radiation Regulation Of Multicellular Organismal Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Developmental Process Negative Regulation Of Inflammatory Response To Antigenic Stimulus Negative Regulation Of Cell Cycle RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Immune System Process Cytoskeleton
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