SNTG1 and DTNA

Number of citations of the paper that reports this interaction (PubMedID 10747910)
0

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SNTG1	DTNA
Description		syntrophin gamma 1	dystrobrevin alpha
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Ruffle Membrane	Nucleoplasm Cytoplasm Plasma Membrane Membrane Cell Junction Axon Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Protein-containing Complex Sarcolemma Cell Projection Intermediate Filament Cytoskeleton Synapse
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding	Protein Binding Zinc Ion Binding PDZ Domain Binding Metal Ion Binding
	Biological Process	Cell Communication	Striated Muscle Contraction Signal Transduction Chemical Synaptic Transmission Neuromuscular Synaptic Transmission Synaptic Signaling
Pathways			Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Age at first sexual intercourse ( 34211149) Diastolic blood pressure ( 27841878) General risk tolerance (MTAG) ( 30643258) Interleukin-6 levels ( 22205395) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Pulmonary function ( 17903307) Pulse pressure ( 27841878) Remission after SSRI treatment in MDD or openness ( 29559929) Response to SSRI in MDD or openness ( 29559929) Superior frontal gyrus grey matter volume ( 25335168) Systolic blood pressure ( 27841878 30578418)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) PR interval ( 32439900) Urate levels in overweight individuals ( 25811787)
Interacting Genes		16 interacting genes: ADRA1D DGKZ DMD DTNA DTNB FGF2 KCNA4 PLEKHA1 PLEKHA2 SNAP23 STXBP3 TGFBR1 UBC VANGL2 VPS45 VTN	16 interacting genes: ACTA1 APPL1 DMD DRP2 DTNBP1 GFI1B KCNJ12 SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 STAT3 SYNC SYNM UTRN
Entrez ID		54212	1837
HPRD ID		16373	03141
Ensembl ID		ENSG00000147481	ENSG00000134769
Uniprot IDs		A0A2R8Y5T2 A0A2R8Y631 B2RA84 Q9NSN8	A0A7P0T9L1 A0A7P0TBH9 A0A7P0Z4D7 B7Z3X3 Q9Y4J8
PDB IDs		7PC7 7PC8 7QQN	2E5R
Enriched GO Terms of Interacting Partners?		Angiogenesis Involved In Coronary Vascular Morphogenesis Plasma Membrane PDZ Domain Binding Wound Healing Specific Granule Membrane Cell-cell Signaling Signaling Cell Communication Phosphatidylinositol-3,4-bisphosphate Binding Alpha1-adrenergic Receptor Activity Striated Muscle Contraction Lateral Plasma Membrane Animal Organ Development Growth Factor Dependent Regulation Of Skeletal Muscle Satellite Cell Proliferation Regulation Of Cardiac Muscle Cell Proliferation Endothelial Cell Proliferation Regulation Of Animal Organ Morphogenesis Response To Wortmannin Positive Regulation Of Inner Ear Receptor Cell Differentiation Negative Regulation Of Wound Healing Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Tube Morphogenesis Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Retinal Cell Programmed Cell Death Cell Migration Animal Organ Morphogenesis Response To Wounding Lymphatic Endothelial Cell Migration Regulation Of Heart Growth Positive Regulation Of Cell Fate Specification Positive Regulation Of Lens Fiber Cell Differentiation Regulation Of Stem Cell Proliferation Endothelial Cell Migration Positive Regulation Of Inner Ear Auditory Receptor Cell Differentiation Cell Motility Positive Regulation Of Stem Cell Proliferation Corticotropin Hormone Secreting Cell Differentiation Syntaxin Binding Tertiary Granule Muscle Tissue Morphogenesis Post-embryonic Development Roof Of Mouth Development Proepicardium Development Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Transforming Growth Factor Beta Ligand-receptor Complex Symbiont-containing Vacuole Smooth Muscle Cell-matrix Adhesion Rough Endoplasmic Reticulum Lumen	Dystrophin-associated Glycoprotein Complex Sarcolemma Syntrophin Complex Muscle Contraction Muscle System Process Actin Binding Vinculin Binding Structural Molecule Activity Cytoskeleton Regulation Of Sodium Ion Transmembrane Transport System Process Regulation Of Sodium Ion Transport Protein-containing Complex Filopodium Nitric-oxide Synthase Binding Neuromuscular Junction PDZ Domain Binding Plasma Membrane Costamere Structural Constituent Of Cytoskeleton Regulation Of Monoatomic Ion Transmembrane Transport Synapse Filopodium Membrane Myosin Binding Regulation Of Transport Positive Regulation Of Endocytosis Anchoring Junction Positive Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Monoatomic Ion Transport Cardiac Muscle Cell Action Potential Structural Constituent Of Muscle Calmodulin Binding Regulation Of Heart Contraction Fast-twitch Skeletal Muscle Fiber Contraction Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Cytoplasm Postsynaptic Membrane Regulation Of Blood Circulation Lateral Plasma Membrane Regulation Of Monoatomic Cation Transmembrane Transport Postsynaptic Density Glutamatergic Synapse Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Neurofilament Cytoskeleton Positive Regulation Of Macropinocytosis Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Actin Cytoskeleton Signaling Striated Muscle Contraction Cell Communication
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