SNTG1 and DMD

Number of citations of the paper that reports this interaction (PMID 10747910)
24

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		SNTG1	DMD
Gene Name		syntrophin, gamma 1	dystrophin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Syntrophin Complex Ruffle Membrane	Nucleus Cytosol Cytoskeleton Plasma Membrane Cell Surface Actin Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Cell Junction Filopodium Filopodium Membrane Sarcolemma Costamere Protein Complex Membrane Raft Postsynaptic Membrane
	Molecular Function	Actin Binding Protein C-terminus Binding	Dystroglycan Binding Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Zinc Ion Binding Structural Constituent Of Muscle Myosin Binding Vinculin Binding Nitric-oxide Synthase Binding
	Biological Process	Cell Communication	Regulation Of Heart Rate Muscle Organ Development Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Neuron Projection Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction Muscle Filament Sliding Extracellular Matrix Organization Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Protein Localization Peptide Biosynthetic Process Cellular Protein Complex Assembly Motile Cilium Assembly Positive Regulation Of Neuron Differentiation Cardiac Muscle Contraction Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cardiac Muscle Cell Action Potential Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Peptidyl-cysteine S-nitrosylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways			Striated Muscle Contraction Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS		Pulmonary function ( 17903307)	Response to antidepressant treatment ( 22041458)
Protein-Protein Interactions		11 interactors: ADRA1D DGKZ DMD DTNA DTNB KCNA4 SNAP23 STXBP3 TGFBR1 UBC VPS45	27 interactors: ACTA1 ACTC1 APP CADPS CADPS2 CDC25A CTNNAL1 DAG1 DGKZ DISC1 DTNA DTNB FASLG HAUS1 KCNJ12 KRT19 KRT8 MAP3K5 PGM5 SGCZ SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 TRAF3IP1 UTRN
Entrez ID		54212	1756
HPRD ID		16373	02303
Ensembl ID		ENSG00000147481	ENSG00000198947
Uniprot IDs		Q9NSN8	A1L0U9 A7E212 P11532 Q16484 Q4G0X0
PDB IDs			1DXX 1EG3 1EG4 3UUN
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Signaling Cell Communication Regulation Of Cellular Response To Growth Factor Stimulus Synaptic Transmission Wound Healing Cell Activation Response To Wounding Leukocyte Degranulation Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Exocytosis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of The Force Of Heart Contraction Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Response To Stimulus Vesicle Docking Striated Muscle Contraction Hormone Secretion Protein Complex Assembly Blood Coagulation Membrane Docking Hemostasis Hormone Transport Mitotic DNA Damage Checkpoint Negative Regulation Of Cell Cycle Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Establishment Of Glial Blood-brain Barrier Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Secretion By Cell Response To Stress Negative Regulation Of Peptidyl-cysteine S-nitrosylation Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Body Fluid Levels Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Phase Transition Cellular Localization DNA Damage Checkpoint Leukocyte Activation Involved In Immune Response Secretion Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Mitotic Cell Cycle Checkpoint	Muscle Contraction Muscle System Process Muscle Cell Development Myofibril Assembly Actomyosin Structure Organization Organelle Assembly Cellular Component Assembly Muscle Structure Development Muscle Cell Differentiation Skeletal Muscle Thin Filament Assembly Striated Muscle Cell Development Skeletal Myofibril Assembly Synaptic Vesicle Priming Striated Muscle Cell Differentiation Organ Development Cytoskeleton Organization Organelle Organization Muscle Organ Development Positive Regulation Of Proteolysis Cell Development System Development Positive Regulation Of Peptidase Activity Cell Differentiation Involved In Embryonic Placenta Development Actin-myosin Filament Sliding Muscle Filament Sliding Movement Of Cell Or Subcellular Component Regulation Of Sodium Ion Transmembrane Transport Microtubule-based Process Actin-mediated Cell Contraction Programmed Necrotic Cell Death Nerve Maturation Regulation Of Vasoconstriction By Circulating Norepinephrine Necrotic Cell Death Multicellular Organismal Development Sarcomere Organization Neuromuscular Junction Development Synaptic Vesicle Exocytosis Anatomical Structure Development Actin Filament-based Movement Cell-cell Signaling Heart Contraction Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Calcium-dependent Cell-matrix Adhesion Regulation Of Sodium Ion Transport Anatomical Structure Morphogenesis Viral Process Apoptotic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Death
Tagcloud ?			2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2
Tagcloud (Difference) ?			2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2
Tagcloud (Intersection) ?