SNTG1 and ADRA1D

Number of citations of the paper that reports this interaction (PMID 16533813)
14

Data Source:
HPRD (in vitro)

		SNTG1	ADRA1D
Gene Name		syntrophin, gamma 1	adrenoceptor alpha 1D
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Syntrophin Complex Ruffle Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Actin Binding Protein C-terminus Binding	Alpha1-adrenergic Receptor Activity
	Biological Process	Cell Communication	Negative Regulation Of The Force Of Heart Contraction Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure DNA Metabolic Process G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling Multicellular Organismal Development Cell Proliferation Positive Regulation Of Cell Proliferation Adrenergic Receptor Signaling Pathway
Pathways			G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding G alpha (q) signalling events GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Adrenoceptors G alpha (12/13) signalling events
Drugs			Dapiprazole Amitriptyline Alfuzosin Norepinephrine Phenylephrine Promazine Prazosin Imipramine Nortriptyline Doxazosin Nicardipine Epinephrine Ergotamine Tamsulosin Propiomazine Doxepin Terazosin Pergolide Bromocriptine Quetiapine Methotrimeprazine Dronedarone Sertindole Silodosin Droxidopa Xylometazoline
Diseases
GWAS		Pulmonary function ( 17903307)	Preeclampsia ( 23551011)
Protein-Protein Interactions		11 interactors: ADRA1D DGKZ DMD DTNA DTNB KCNA4 SNAP23 STXBP3 TGFBR1 UBC VPS45	8 interactors: ADRA1A FLNC LNX1 NOS1 SNTA1 SNTB1 SNTB2 SNTG1
Entrez ID		54212	146
HPRD ID		16373	00079
Ensembl ID		ENSG00000147481	ENSG00000171873
Uniprot IDs		Q9NSN8	B0ZBE0 P25100
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Signaling Cell Communication Regulation Of Cellular Response To Growth Factor Stimulus Synaptic Transmission Wound Healing Cell Activation Response To Wounding Leukocyte Degranulation Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Exocytosis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of The Force Of Heart Contraction Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Response To Stimulus Vesicle Docking Striated Muscle Contraction Hormone Secretion Protein Complex Assembly Blood Coagulation Membrane Docking Hemostasis Hormone Transport Mitotic DNA Damage Checkpoint Negative Regulation Of Cell Cycle Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Establishment Of Glial Blood-brain Barrier Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Secretion By Cell Response To Stress Negative Regulation Of Peptidyl-cysteine S-nitrosylation Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Body Fluid Levels Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Phase Transition Cellular Localization DNA Damage Checkpoint Leukocyte Activation Involved In Immune Response Secretion Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Mitotic Cell Cycle Checkpoint	Muscle Contraction Muscle System Process Regulation Of Cardiac Muscle Contraction Regulation Of Striated Muscle Contraction Regulation Of Muscle Contraction Regulation Of Heart Contraction Regulation Of The Force Of Heart Contraction Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Blood Pressure Regulation Of Vasoconstriction Regulation Of Sodium Ion Transport Regulation Of Heart Rate Regulation Of Vasoconstriction By Circulating Norepinephrine Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Negative Regulation Of The Force Of Heart Contraction Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of Serotonin Uptake Positive Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Adrenergic Receptor Signaling Pathway Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine Regulation Of Generation Of L-type Calcium Current Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Positive Regulation Of The Force Of Heart Contraction Pilomotor Reflex Regulation Of Blood Pressure Negative Regulation Of Peptidyl-cysteine S-nitrosylation Peptidyl-cysteine S-nitrosylation Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Regulation Of Adrenergic Receptor Signaling Pathway Positive Regulation Of Heart Rate By Epinephrine-norepinephrine Striated Muscle Cell Differentiation Micturition Positive Regulation Of Cardiac Muscle Contraction Arginine Catabolic Process Regulation Of The Force Of Heart Contraction By Chemical Signal Negative Regulation Of Calcium Ion Transport Into Cytosol Positive Regulation Of Action Potential Positive Regulation Of Protein Kinase C Signaling Negative Regulation Of Heart Rate Positive Regulation Of Guanylate Cyclase Activity Positive Regulation Of Striated Muscle Contraction Regulation Of Synaptic Transmission Blood Circulation Muscle Cell Differentiation Positive Regulation Of Systemic Arterial Blood Pressure Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Nitric Oxide Biosynthetic Process Adrenergic Receptor Signaling Pathway
Tagcloud ?			aminobutyric attentional caregivers catecholaminergic classes covariates departments descriptive encode ergic gaba gabaergic genotypic htr2a latent membership multivariable neurotransmission oncology rs2296972 rs2697138 rs37022 rs4815675 rs9534496 serotonergic slc6a1 slc6a3 trajectories variations
Tagcloud (Difference) ?			aminobutyric attentional caregivers catecholaminergic classes covariates departments descriptive encode ergic gaba gabaergic genotypic htr2a latent membership multivariable neurotransmission oncology rs2296972 rs2697138 rs37022 rs4815675 rs9534496 serotonergic slc6a1 slc6a3 trajectories variations
Tagcloud (Intersection) ?