CYCS and APAF1

  • Number of citations of the paper that reports this interaction (PMID 9267021)
  • 387
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

CYCS

APAF1

Gene Name cytochrome c, somatic apoptotic peptidase activating factor 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (cognitive decline) ( 23535033)
Protein-Protein Interactions 20 interactors: AGTPBP1 APAF1 BCL2 BCL2L1 CASP9 COX4I2 CYB5A CYB5R1 CYB5R3 CYC1 FDX1 HSPA8 HSPB1 KRT40 NDOR1 RNF7 SAFB SNCA UQCRC1 VDAC2 18 interactors: APIP AVEN BCL2L1 BCL2L10 CASP3 CASP4 CASP8 CASP9 CYCS FAS FEM1B HIP1 HSP90AA1 HSPA1A NLRP1 PPP1CA TOP1 TRIAP1
Entrez ID 54205 317
HPRD ID 00479 03755
Ensembl ID ENSG00000120868
Uniprot IDs G4XXL9 P99999 O14727
PDB IDs 1J3S 3NWV 1C15 1CWW 1CY5 1Z6T 2P1H 2YGS 3J2T 3YGS
Enriched GO Terms of Interacting Partners?
Tagcloud ?
alternate  apical  apoptosome  apoptotic  atg5  atg7  autophagic  autophagosome  autophagy  bak1  casp8  casp9  caspase  caspases  chemoresistance  coincides  cytochrome  defective  devoid  existence  facilitating  fadd  highlighting  impacted  normally  platform  problem  revealing  tackling 
alleviate  amounts  angiogenesis  anthocyanins  bace2  brings  confirm  downregulate  downregulated  enriched  fruit  great  microarray  microarrays  modulated  mtt  mulberry  mumol  neuroprotection  neuroprotective  neutralize  nutrigenomics  pc12  peptidase  plcb4  preincubated  preincubation  pretreatment  substantially 
Tagcloud (Difference) ?
alternate  apical  apoptosome  apoptotic  atg5  atg7  autophagic  autophagosome  autophagy  bak1  casp8  casp9  caspase  caspases  chemoresistance  coincides  cytochrome  defective  devoid  existence  facilitating  fadd  highlighting  impacted  normally  platform  problem  revealing  tackling 
alleviate  amounts  angiogenesis  anthocyanins  bace2  brings  confirm  downregulate  downregulated  enriched  fruit  great  microarray  microarrays  modulated  mtt  mulberry  mumol  neuroprotection  neuroprotective  neutralize  nutrigenomics  pc12  peptidase  plcb4  preincubated  preincubation  pretreatment  substantially 
Tagcloud (Intersection) ?