PIK3R2 and IRS2

  • Number of citations of the paper that reports this interaction (PMID 9651378)
  • 36
  • Data Source:
  • HPRD (in vivo, in vitro)

PIK3R2

IRS2

Gene Name phosphoinositide-3-kinase, regulatory subunit 2 (beta) insulin receptor substrate 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 51 interactors: APP ARRB1 AXL CBL CD28 CRKL CSF1 CSF1R DYDC1 EGF EGFR EPHA2 ERBB2 ERBB3 ERBB4 FBXL2 FGFR1 FYN GOLGA2 GRB2 GRN HCK IGF1R IKZF3 IRS1 IRS2 KIT KRAS KRT15 KRT20 KRT38 LAMB2 LTBP3 MRFAP1L1 PDGFRB PIK3CD RINT1 SEPT2 SHC1 SOCS1 SOCS6 SOCS7 SOS1 STAB1 SYK TEC TGFBR1 TGFBR2 TRIM23 WASF3 YWHAB 38 interactors: ATP2A1 ATP2A2 BCL2L1 CRK EPOR FES GRB2 IGF1R IL4R INSR JAK1 JAK2 JAK3 MPL NTRK1 PIK3CA PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PTPN11 PTPN6 PTPRF RPTOR SHC1 SIRT1 SOCS1 SOCS3 SOCS6 SOCS7 TYK2 UBTF YWHAB YWHAE YWHAG YWHAQ YWHAZ
Entrez ID 5296 8660
HPRD ID 04404 02878
Ensembl ID ENSG00000105647 ENSG00000185950
Uniprot IDs O00459 Q9P084 Q9Y4H2
PDB IDs 2KT1 2XS6 3MTT 3O5Z 3FQW 3FQX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acetylated  acetylations  chip  contrary  deacetylase  deacetylases  distally  dysregulated  encompassing  facilitates  featured  h2a  h3k9  hexokinase  hk2  irs2  l6  lysines  myotubes  p85beta  pharmacologically  responsive  reverted  template  treatable  trichostatin  tsa  tss  z 
aacr  adaptive  adaptor  compensatory  conversely  cotargeting  dampen  dasatinib  ddr2  driven  emerged  gab1  harboring  igf1r  implicating  library  met  option  overlaying  panel  phosphoproteomics  py  rationale  res  rescued  rtk  scc  synergistic  weakly 
Tagcloud (Difference) ?
acetylated  acetylations  chip  contrary  deacetylase  deacetylases  distally  dysregulated  encompassing  facilitates  featured  h2a  h3k9  hexokinase  hk2  l6  lysines  myotubes  p85beta  pharmacologically  responsive  reverted  template  treatable  trichostatin  tsa  tss  z 
aacr  adaptive  adaptor  compensatory  conversely  cotargeting  dampen  dasatinib  ddr2  driven  emerged  gab1  harboring  igf1r  implicating  library  met  option  overlaying  panel  phosphoproteomics  py  rationale  res  rescued  rtk  scc  synergistic  weakly 
Tagcloud (Intersection) ?
irs2