PHF1 and HSD17B14

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PHF1	HSD17B14
Gene Name		PHD finger protein 1	hydroxysteroid (17-beta) dehydrogenase 14
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center ESC/E(Z) Complex Site Of Double-strand Break	Cytosol
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Zinc Ion Binding Methylated Histone Binding	Estradiol 17-beta-dehydrogenase Activity Protein Binding Testosterone 17-beta-dehydrogenase (NADP+) Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Gene Expression Chromatin Modification Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation	Steroid Catabolic Process Oxidation-reduction Process
Pathways		Epigenetic regulation of gene expression PRC2 methylates histones and DNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ATXN7L1 BIRC7 CALCOCO2 EZH2 HIST1H3A HIST1H3B HIST1H3C HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HSD17B14 NAB2 NEK6 PDLIM7 RBPMS TFCP2 THAP1 TRIM23 VAC14	15 interactors: CA8 CDKN2D DDIT3 LINC00152 MIR4435-1HG MPG NEK6 NUDT18 PHF1 PSMA1 SNAPC3 SNRPC SREK1IP1 TBC1D22B WDYHV1
Entrez ID		5252	51171
HPRD ID		04195	16801
Ensembl ID		ENSG00000112511	ENSG00000087076
Uniprot IDs		O43189	Q9BPX1
PDB IDs		2E5P 2M0O 4HCZ	1YDE
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Nucleosome Assembly DNA Methylation On Cytosine Chromatin Silencing At RDNA Regulation Of Gene Silencing DNA Methylation Chromatin Silencing Negative Regulation Of Gene Expression, Epigenetic DNA Modification Gene Silencing Nucleosome Assembly Regulation Of Gene Expression, Epigenetic Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Methylation DNA Conformation Change Wound Healing Blood Coagulation Hemostasis Response To Wounding Chromatin Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Body Fluid Levels Cellular Macromolecular Complex Assembly Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromosome Organization Protein Complex Assembly DNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Gene Expression Regulation Of Metabolic Process Response To Stress Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Component Assembly Regulation Of RNA Metabolic Process Organelle Organization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process	Cellular Response To DNA Damage Stimulus Deoxyribose Phosphate Catabolic Process Cellular Response To Stress Deoxyribonucleotide Catabolic Process Purine Nucleotide Catabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Deoxyribonucleotide Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Determination Of Dorsal Identity GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process Nucleotide Catabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription Involved In Anterior/posterior Axis Specification Regulation Of Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Apoptotic Process Depurination Negative Regulation Of Cell Cycle Programmed Cell Death Cell Cycle Process Cell Death Death MRNA 5'-splice Site Recognition Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Regulation Of Cellular Protein Metabolic Process Cell Cycle Arrest Organophosphate Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway DNA Damage Checkpoint Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process G1/S Transition Of Mitotic Cell Cycle DNA Dealkylation Involved In DNA Repair Autophagic Cell Death Base-excision Repair, AP Site Formation Ribonucleoside Diphosphate Catabolic Process Regulation Of Protein Metabolic Process Nucleoside Diphosphate Catabolic Process Cell Cycle Negative Regulation Of Wnt Signaling Pathway Regulation Of Proteolysis SnRNA Transcription ER Overload Response Mitotic Cell Cycle Process Response To Stress
Tagcloud ?		12e8 albeit at180 axon dendrite enter enters fyn glutamic map2 p301l pseudophosphorylated pseudophosphorylation replacements s235 s262 s356 s396 s404 s422 shaft shares spine spines synaptosomal t231 tau tau1 vastly
Tagcloud (Difference) ?		12e8 albeit at180 axon dendrite enter enters fyn glutamic map2 p301l pseudophosphorylated pseudophosphorylation replacements s235 s262 s356 s396 s404 s422 shaft shares spine spines synaptosomal t231 tau tau1 vastly
Tagcloud (Intersection) ?