HSD17B14 and WDYHV1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		HSD17B14	WDYHV1
Gene Name		hydroxysteroid (17-beta) dehydrogenase 14	WDYHV motif containing 1
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Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus Cytosol
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Testosterone 17-beta-dehydrogenase (NADP+) Activity	Protein Binding Protein-N-terminal Glutamine Amidohydrolase Activity
	Biological Process	Steroid Catabolic Process Oxidation-reduction Process	Cellular Protein Modification Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: CA8 CDKN2D DDIT3 LINC00152 MIR4435-1HG MPG NEK6 NUDT18 PHF1 PSMA1 SNAPC3 SNRPC SREK1IP1 TBC1D22B WDYHV1	88 interactors: ACTB ACTG1 AMOT AMOTL2 APIP ASL BIRC2 BLMH BLOC1S6 C1orf50 CAPN3 CBFA2T2 CCDC102B CCDC184 CDA CDR2 COIL CRYAA CTH DAB1 DCTPP1 DHPS EDARADD EIF2B1 ETV6 FTH1 GAS7 GMDS GNMT GOLGA2 HPRT1 HSD17B14 JUP KCNH1 KCTD1 KLHL12 KRT31 KRTAP10-5 KRTAP10-7 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LONRF1 LZTFL1 LZTS2 MAGEA11 MARCH10 MDFI MIF MTUS2 NCOA5 NECAB2 NME1 NPL NT5C1A NUDT14 PCBD1 PNMA1 PNMA5 PPCDC PRMT1 PRPS2 PTS PYGM RABAC1 RAD54L RBBP8 RBPMS RPIA SEPT3 SFN SIAH1 SMN1 STX11 THAP1 TMEM239 TNR TOLLIP TRIM27 TRIM54 TRIP13 TSC22D1 VAC14 VCP XIAP ZBTB8A ZNF341
Entrez ID		51171	55093
HPRD ID		16801	07653
Ensembl ID		ENSG00000087076	ENSG00000156795
Uniprot IDs		Q9BPX1	Q96HA8
PDB IDs		1YDE	3C9Q
Enriched GO Terms of Interacting Partners?		Cellular Response To DNA Damage Stimulus Deoxyribose Phosphate Catabolic Process Cellular Response To Stress Deoxyribonucleotide Catabolic Process Purine Nucleotide Catabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Deoxyribonucleotide Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Determination Of Dorsal Identity GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process Nucleotide Catabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription Involved In Anterior/posterior Axis Specification Regulation Of Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Apoptotic Process Depurination Negative Regulation Of Cell Cycle Programmed Cell Death Cell Cycle Process Cell Death Death MRNA 5'-splice Site Recognition Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Regulation Of Cellular Protein Metabolic Process Cell Cycle Arrest Organophosphate Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway DNA Damage Checkpoint Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process G1/S Transition Of Mitotic Cell Cycle DNA Dealkylation Involved In DNA Repair Autophagic Cell Death Base-excision Repair, AP Site Formation Ribonucleoside Diphosphate Catabolic Process Regulation Of Protein Metabolic Process Nucleoside Diphosphate Catabolic Process Cell Cycle Negative Regulation Of Wnt Signaling Pathway Regulation Of Proteolysis SnRNA Transcription ER Overload Response Mitotic Cell Cycle Process Response To Stress	Protein Oligomerization Protein Complex Assembly Protein Homooligomerization Cellular Component Assembly Protein Homotetramerization Protein Tetramerization Nucleobase-containing Small Molecule Metabolic Process Nucleoside Metabolic Process Catabolic Process Cellular Nitrogen Compound Metabolic Process Purine Nucleoside Metabolic Process Anatomical Structure Development Small Molecule Metabolic Process Developmental Process Biosynthetic Process Cell Differentiation Nitrogen Compound Metabolic Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Apoptotic Process Cellular Metabolic Process Purine Nucleoside Monophosphate Catabolic Process Regulation Of Cell Death Tetrahydrobiopterin Biosynthetic Process Cell Development Nucleotide Metabolic Process System Development Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Ubiquitination Sulfur Amino Acid Metabolic Process Multicellular Organismal Development Aromatic Compound Catabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Modification By Small Protein Conjugation Cofactor Metabolic Process Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Neuron Projection Development Regulation Of Metabolic Process Organophosphate Metabolic Process Cellular Modified Amino Acid Metabolic Process Regulation Of Cellular Localization Membrane Organization Response To Stimulus Organophosphate Catabolic Process Double-strand Break Repair Cellular Process S-adenosylmethionine Metabolic Process Pyrimidine Nucleoside Metabolic Process
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