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HSD17B14 and CDKN2D
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
HSD17B14
CDKN2D
Description
hydroxysteroid 17-beta dehydrogenase 14
cyclin dependent kinase inhibitor 2D
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cyclin D2-CDK4 Complex
Molecular Function
Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity
Protein Binding
Oxidoreductase Activity
Identical Protein Binding
D-threo-aldose 1-dehydrogenase Activity
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Protein Binding
Protein Kinase Binding
Biological Process
Fucose Metabolic Process
Lipid Metabolic Process
Steroid Metabolic Process
L-fucose Catabolic Process
DNA Synthesis Involved In DNA Repair
Sensory Perception Of Sound
Negative Regulation Of Cell Population Proliferation
Response To UV
Negative Regulation Of Cell Growth
Response To Retinoic Acid
Response To Vitamin D
Autophagic Cell Death
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of Cell Cycle G1/S Phase Transition
Negative Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Estrogen biosynthesis
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
Oncogene Induced Senescence
Cyclin D associated events in G1
Drugs
Diseases
GWAS
Blood protein levels (
30072576
)
Resting metabolic rate (
28476931
)
Lymphocyte percentage of white cells (
32888494
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red blood cell count (
32888494
)
Red cell distribution width (
32888494
)
Interacting Genes
24 interacting genes:
AKIRIN2
BRIP1
CA8
CDKN2D
CYTOR
DDIT3
INCA1
MIA3
MIR4435-2HG
MPG
NEK6
NTAQ1
NUDT18
OTUD3
PGLYRP3
PHF1
PICK1
PIDD1
PSMA1
REL
SNAPC3
SNRPC
SREK1IP1
TBC1D22B
63 interacting genes:
APP
BRCA1
BTG1
C1orf94
CCND3
CDK4
CDK6
CFAP90
CGGBP1
CTBP1
DDIT4L
DMRTB1
DYNLT2B
EIF4G1
FAM228A
FAM86C1P
FHL3
GATAD2B
GLYR1
GORASP2
GSC2
HSD17B14
IKZF3
INCA1
KRT75
LNX1
LONRF1
LSM3
MEI4
MEOX2
MSS51
MTF2
NDUFB7
NIF3L1
NME4
NMI
NR4A1
NR4A2
NR4A3
PICK1
PRDX5
PRIMPOL
PSMA1
QKI
REL
RUFY4
SAXO1
SDCBP
SH3GLB1
SH3GLB2
TBC1D17
TEX11
THAP1
TSG101
TSGA10IP
UQCC2
VGLL1
YPEL3
ZBTB32
ZNF396
ZNF620
ZNF688
ZNF774
Entrez ID
51171
1032
HPRD ID
16801
02957
Ensembl ID
ENSG00000087076
ENSG00000129355
Uniprot IDs
A0A140VJH8
Q9BPX1
P55273
PDB IDs
1YDE
5EN4
5HS6
5ICM
5ICS
5JS6
5JSF
5L7T
5L7W
5L7Y
5O42
5O43
5O6O
5O6X
5O6Z
5O72
5O7C
6EMM
6FFB
6G4L
6GBT
6GTB
6GTU
6H0M
6HNO
6QCK
6ZDE
6ZDI
6ZR6
6ZRA
6ZT2
1BD8
1BI8
Enriched GO Terms of Interacting Partners
?
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Response To Corticotropin-releasing Hormone Stimulus
Regulation Of Transcription By RNA Polymerase II
Sequence-specific DNA Binding
Regulation Of RNA Metabolic Process
Protein Binding
Regulation Of Macromolecule Biosynthetic Process
DNA Binding
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of DNA-templated Transcription
Cyclin D3-CDK6 Complex
Cyclin D3-CDK4 Complex
Regulation Of Type B Pancreatic Cell Proliferation
Regulation Of Nucleobase-containing Compound Metabolic Process
Nuclear Glucocorticoid Receptor Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Cell Cycle
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Zinc Ion Binding
Regulation Of Organelle Assembly
Regulation Of Primary Metabolic Process
Nucleus
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Chromatin
Cyclin-dependent Protein Serine/threonine Kinase Activity
Identical Protein Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Regulation Of Extracellular Exosome Assembly
Negative Regulation Of Metabolic Process
Cyclin Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Regulation Of Mitotic Cell Cycle
Cyclin-dependent Protein Kinase Holoenzyme Complex
Negative Regulation Of Type I Interferon Production
DNA-binding Transcription Factor Activity
Nuclear Receptor Activity
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Tagcloud (Difference)
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Tagcloud (Intersection)
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